CA1057254A - Disposable centrifugal blood processing system - Google Patents
Disposable centrifugal blood processing systemInfo
- Publication number
- CA1057254A CA1057254A CA258,070A CA258070A CA1057254A CA 1057254 A CA1057254 A CA 1057254A CA 258070 A CA258070 A CA 258070A CA 1057254 A CA1057254 A CA 1057254A
- Authority
- CA
- Canada
- Prior art keywords
- casing
- shell
- centrifugal separator
- disposable
- outer shell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000004369 blood Anatomy 0.000 title claims abstract description 51
- 239000008280 blood Substances 0.000 title claims abstract description 51
- 238000012545 processing Methods 0.000 title claims abstract description 18
- 238000000926 separation method Methods 0.000 claims abstract description 35
- 238000005119 centrifugation Methods 0.000 claims description 14
- 210000000265 leukocyte Anatomy 0.000 claims description 13
- 239000012530 fluid Substances 0.000 claims description 12
- 210000002381 plasma Anatomy 0.000 claims description 12
- 210000003743 erythrocyte Anatomy 0.000 claims description 10
- 239000004033 plastic Substances 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 5
- 238000003860 storage Methods 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 3
- 239000004417 polycarbonate Substances 0.000 claims description 3
- 229920000515 polycarbonate Polymers 0.000 claims description 3
- 238000012546 transfer Methods 0.000 claims description 2
- 239000000306 component Substances 0.000 description 10
- 230000002572 peristaltic effect Effects 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 239000012503 blood component Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000000465 moulding Methods 0.000 description 3
- 125000006850 spacer group Chemical group 0.000 description 3
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 210000001772 blood platelet Anatomy 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 238000005461 lubrication Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- IJRKANNOPXMZSG-SSPAHAAFSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O.OC(=O)CC(O)(C(O)=O)CC(O)=O IJRKANNOPXMZSG-SSPAHAAFSA-N 0.000 description 1
- 241000237074 Centris Species 0.000 description 1
- 241000905957 Channa melasoma Species 0.000 description 1
- 229920004142 LEXAN™ Polymers 0.000 description 1
- 239000004418 Lexan Substances 0.000 description 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 210000001754 blood buffy coat Anatomy 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000006261 foam material Substances 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- JCYWCSGERIELPG-UHFFFAOYSA-N imes Chemical class CC1=CC(C)=CC(C)=C1N1C=CN(C=2C(=CC(C)=CC=2C)C)[C]1 JCYWCSGERIELPG-UHFFFAOYSA-N 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000003973 irrigation Methods 0.000 description 1
- 230000002262 irrigation Effects 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229920000260 silastic Polymers 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000007666 vacuum forming Methods 0.000 description 1
- ACWBQPMHZXGDFX-QFIPXVFZSA-N valsartan Chemical class C1=CC(CN(C(=O)CCCC)[C@@H](C(C)C)C(O)=O)=CC=C1C1=CC=CC=C1C1=NN=NN1 ACWBQPMHZXGDFX-QFIPXVFZSA-N 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
- B04B5/0428—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
- B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Centrifugal Separators (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- External Artificial Organs (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA314,222A CA1068658A (en) | 1976-05-14 | 1978-10-25 | Disposable centrifugal blood processing system |
| CA314,221A CA1068657A (en) | 1976-05-14 | 1978-10-25 | Disposable centrifugal blood processing system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68729076A | 1976-05-14 | 1976-05-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1057254A true CA1057254A (en) | 1979-06-26 |
Family
ID=24759855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA258,070A Expired CA1057254A (en) | 1976-05-14 | 1976-07-29 | Disposable centrifugal blood processing system |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS6050497B2 (Direct) |
| CA (1) | CA1057254A (Direct) |
| CH (1) | CH624023A5 (Direct) |
| DE (1) | DE2717344C2 (Direct) |
| FR (1) | FR2350885A1 (Direct) |
| IL (1) | IL51629A (Direct) |
| IT (1) | IT1084675B (Direct) |
| NL (1) | NL7705334A (Direct) |
| NO (1) | NO146848C (Direct) |
| SE (1) | SE427138B (Direct) |
| SU (1) | SU1072794A3 (Direct) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4094461A (en) * | 1977-06-27 | 1978-06-13 | International Business Machines Corporation | Centrifuge collecting chamber |
| JPS5819344B2 (ja) * | 1979-02-26 | 1983-04-18 | テルモ株式会社 | 流体の遠心分離装置 |
| US4344560A (en) * | 1979-11-02 | 1982-08-17 | Asahi Kasei Kogyo Kabushiki Kaisha | Container, apparatus and method for separating platelets |
| US4389206A (en) * | 1980-10-09 | 1983-06-21 | Baxter Travenol Laboratories, Inc. | Centrifugal processing apparatus and rotatable processing bowl apparatus |
| US4389207A (en) | 1981-03-16 | 1983-06-21 | Baxter Travenol Laboratories, Inc. | Rotatable bowl assembly for centrifugal processing apparatus having a bonded and prewound umbilical system |
| GB8521867D0 (en) * | 1985-09-03 | 1985-10-09 | Fisons Plc | Centrifuge |
| US4834890A (en) * | 1987-01-30 | 1989-05-30 | Baxter International Inc. | Centrifugation pheresis system |
| US4939087A (en) * | 1987-05-12 | 1990-07-03 | Washington State University Research Foundation, Inc. | Method for continuous centrifugal bioprocessing |
| DE19728089A1 (de) * | 1997-07-02 | 1999-01-07 | Fresenius Ag | Verfahren zum Separieren einer Zellsuspension durch Zentrifugieren, insbesondere zum Trennen von Vollblut in seine Blutkomponenten |
| DE19810195A1 (de) * | 1998-03-10 | 1999-09-23 | Reinhard Salinger | Verfahren und Vorrichtung zur Sammlung und Weiterverarbeitung von spezifischen Blutkomponenten bei kontinuierlichen laminaren Strömungsverhältnissen |
| IT1311989B1 (it) | 1999-03-30 | 2002-03-22 | Giammaria Sitar | Procedimento per isolare cellule fetali presenti nel sangue perifericomaterno. |
| US6500107B2 (en) * | 2001-06-05 | 2002-12-31 | Baxter International, Inc. | Method for the concentration of fluid-borne pathogens |
| US20060226087A1 (en) * | 2005-04-08 | 2006-10-12 | Mission Medical, Inc. | Method and apparatus for blood separations |
| JP5285060B2 (ja) * | 2008-03-12 | 2013-09-11 | 山科精器株式会社 | 遠心分離装置 |
| KR102568314B1 (ko) * | 2018-06-08 | 2023-08-18 | 뉴메틱 스케일 코포레이션 | 현탁액 내 세포를 분리하기 위한 원심 분리 시스템 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UST955355I4 (Direct) * | 1959-06-24 | 1900-01-01 | ||
| US3489145A (en) * | 1966-08-08 | 1970-01-13 | Surgeon General Of The Public | Method and apparatus for continuous separation of blood in vivo |
| US3655123A (en) * | 1966-08-08 | 1972-04-11 | Us Health Education & Welfare | Continuous flow blood separator |
| US3519201A (en) * | 1968-05-07 | 1970-07-07 | Us Health Education & Welfare | Seal means for blood separator and the like |
| DE2353227A1 (de) * | 1973-10-24 | 1975-05-07 | Rohe Scientific Corp | Probebehaelter zur verwendung beim zentrifugieren |
| US4059108A (en) * | 1974-08-15 | 1977-11-22 | Haemonetics Corporation | Process for pheresis procedure and disposable pheresis bowl therefor |
| US3955755A (en) * | 1975-04-25 | 1976-05-11 | The United States Of America As Represented By The United States Energy Research And Development Administration | Closed continuous-flow centrifuge rotor |
-
1976
- 1976-07-29 CA CA258,070A patent/CA1057254A/en not_active Expired
-
1977
- 1977-03-08 IL IL51629A patent/IL51629A/en unknown
- 1977-03-17 FR FR7708053A patent/FR2350885A1/fr active Granted
- 1977-04-07 SE SE7704127A patent/SE427138B/xx unknown
- 1977-04-19 DE DE2717344A patent/DE2717344C2/de not_active Expired
- 1977-04-26 CH CH517377A patent/CH624023A5/de not_active IP Right Cessation
- 1977-05-03 NO NO771540A patent/NO146848C/no unknown
- 1977-05-09 IT IT23345/77A patent/IT1084675B/it active
- 1977-05-10 JP JP52054173A patent/JPS6050497B2/ja not_active Expired
- 1977-05-13 NL NL7705334A patent/NL7705334A/xx not_active Application Discontinuation
- 1977-05-13 SU SU772481957A patent/SU1072794A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| JPS52138761A (en) | 1977-11-19 |
| SE7704127L (sv) | 1977-11-15 |
| DE2717344A1 (de) | 1977-11-24 |
| IL51629A (en) | 1979-11-30 |
| NO146848C (no) | 1982-12-22 |
| SE427138B (sv) | 1983-03-07 |
| NL7705334A (nl) | 1977-11-16 |
| SU1072794A3 (ru) | 1984-02-07 |
| FR2350885A1 (fr) | 1977-12-09 |
| IL51629A0 (en) | 1977-05-31 |
| FR2350885B1 (Direct) | 1982-06-11 |
| NO146848B (no) | 1982-09-13 |
| JPS6050497B2 (ja) | 1985-11-08 |
| NO771540L (no) | 1977-11-15 |
| CH624023A5 (en) | 1981-07-15 |
| IT1084675B (it) | 1985-05-28 |
| DE2717344C2 (de) | 1987-02-05 |
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