CA1051896A - Method of producing psychotropically and antimicrobially effective polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepin - Google Patents
Method of producing psychotropically and antimicrobially effective polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepinInfo
- Publication number
- CA1051896A CA1051896A CA243,125A CA243125A CA1051896A CA 1051896 A CA1051896 A CA 1051896A CA 243125 A CA243125 A CA 243125A CA 1051896 A CA1051896 A CA 1051896A
- Authority
- CA
- Canada
- Prior art keywords
- benzene
- thiepin
- mixture
- solution
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
- C07C17/14—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS9575 | 1975-01-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1051896A true CA1051896A (en) | 1979-04-03 |
Family
ID=5332480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA243,125A Expired CA1051896A (en) | 1975-01-06 | 1976-01-06 | Method of producing psychotropically and antimicrobially effective polysubstituted derivatives of 10-piperazinodibenzo (b,f) thiepin |
Country Status (14)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS196893B1 (en) * | 1977-12-22 | 1980-04-30 | Miroslav Protiva | 3-fluor-10-piperazino-8-substituted 10,11-dihydro-dibenzothiepines |
| DE3029365A1 (de) * | 1980-08-01 | 1982-03-25 | Bayer Ag, 5090 Leverkusen | Verfahren zur (alpha)-bromierung von gegebenenfalls substituierten fluortoluolen und gemischen von in (alpha)-stellung verschieden hoch bromierten, gegebenenfalls substituierten fluortoluolen |
| US4656173A (en) * | 1985-04-24 | 1987-04-07 | Bristol-Myers Company | Antipsychotic benzisothiazole S-oxide compound |
| JP2907856B2 (ja) * | 1989-03-10 | 1999-06-21 | 日立精工株式会社 | 研削砥石のドレッシング方法 |
| GB0415320D0 (en) * | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2412520C2 (de) * | 1973-03-30 | 1982-09-16 | F. Hoffmann-La Roche & Co. AG, 4002 Basel | Tricyclische Verbindungen, Verfahren zu deren Herstellung und diese enthaltende Präparate |
| US4011222A (en) * | 1973-03-30 | 1977-03-08 | Hoffmann-La Roche Inc. | Fluoro-substituted dibenzo[b,f]thiepins |
| US3954769A (en) * | 1973-03-30 | 1976-05-04 | Hoffman-La Roche Inc. | Dibenzo[b,f]thiepins |
| US3928383A (en) * | 1973-06-08 | 1975-12-23 | Hoffmann La Roche | Propynylamine-substituted dibenzo{8 b,f{9 thiepins and dibenz{8 b,f{9 oxepins |
-
1975
- 1975-12-22 FI FI753625A patent/FI753625A/fi not_active Application Discontinuation
- 1975-12-24 AT AT985075A patent/AT347470B/de not_active IP Right Cessation
- 1975-12-31 GB GB53265/75A patent/GB1497700A/en not_active Expired
-
1976
- 1976-01-05 CH CH1376A patent/CH618698A5/de not_active IP Right Cessation
- 1976-01-05 ES ES444091A patent/ES444091A1/es not_active Expired
- 1976-01-05 DE DE19762600182 patent/DE2600182A1/de not_active Withdrawn
- 1976-01-06 BE BE163328A patent/BE837330A/xx unknown
- 1976-01-06 FR FR7600201A patent/FR2296421A1/fr active Granted
- 1976-01-06 JP JP51001106A patent/JPS5198284A/ja active Pending
- 1976-01-06 US US05/646,755 patent/US4238611A/en not_active Expired - Lifetime
- 1976-01-06 CA CA243,125A patent/CA1051896A/en not_active Expired
- 1976-01-06 NL NL7600097A patent/NL7600097A/xx not_active Application Discontinuation
- 1976-01-06 DK DK3376*#A patent/DK3376A/da not_active Application Discontinuation
- 1976-01-21 AR AR261837A patent/AR211854A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| FR2296421B1 (US20080094685A1-20080424-C00004.png) | 1979-09-21 |
| FR2296421A1 (fr) | 1976-07-30 |
| US4238611A (en) | 1980-12-09 |
| DK3376A (da) | 1976-07-07 |
| ES444091A1 (es) | 1977-04-16 |
| CH618698A5 (US20080094685A1-20080424-C00004.png) | 1980-08-15 |
| ATA985075A (de) | 1978-05-15 |
| DE2600182A1 (de) | 1976-07-08 |
| GB1497700A (en) | 1978-01-12 |
| FI753625A (US20080094685A1-20080424-C00004.png) | 1976-07-07 |
| AU8799175A (en) | 1977-07-14 |
| NL7600097A (nl) | 1976-07-08 |
| BE837330A (fr) | 1976-05-03 |
| AT347470B (de) | 1978-12-27 |
| JPS5198284A (en) | 1976-08-30 |
| AR211854A1 (es) | 1978-03-31 |
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