CA1045547A - Capsule, especially for medicaments - Google Patents
Capsule, especially for medicamentsInfo
- Publication number
- CA1045547A CA1045547A CA229,089A CA229089A CA1045547A CA 1045547 A CA1045547 A CA 1045547A CA 229089 A CA229089 A CA 229089A CA 1045547 A CA1045547 A CA 1045547A
- Authority
- CA
- Canada
- Prior art keywords
- cap
- tooth
- capsule
- projections
- wall
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
Abstract
A B S T R A C T
A hard gelatin capsule, especially for medicaments, having a cylindrical body and a cylindrical cap that telescopes over the open end of the body in which the interior surface of the cap, which overlaps the body, is provided with toothlike projections spaced around the circumference thereof to lock the body and cap against relative axial and rotational movement. In a preferred form of the invention the projections have gently-sloping side walls in both the lateral (circumferential) and longitudinal (axial) directions, which facilitate removing the cap from the dipping pin on which it is formed.
A hard gelatin capsule, especially for medicaments, having a cylindrical body and a cylindrical cap that telescopes over the open end of the body in which the interior surface of the cap, which overlaps the body, is provided with toothlike projections spaced around the circumference thereof to lock the body and cap against relative axial and rotational movement. In a preferred form of the invention the projections have gently-sloping side walls in both the lateral (circumferential) and longitudinal (axial) directions, which facilitate removing the cap from the dipping pin on which it is formed.
Description
55~7 PR IOR AR T
C~apsules consisting of telescopic parts have been known for a long time. U. S. Patent 525, 845 of 1894 describe~ a telescopic capsule, comprising a cap, having an annular constriction approximately in the middle and flares toward it3 open end. The capsule body is designed to be embraced by the annular constrictioll -when the parts of the cap~ule are fitted together. This allegedly results in a good fit of the cap of the capsule on the body thereof.
In another capsule, 3uch ~8 i~ shown in U.S. Patent
C~apsules consisting of telescopic parts have been known for a long time. U. S. Patent 525, 845 of 1894 describe~ a telescopic capsule, comprising a cap, having an annular constriction approximately in the middle and flares toward it3 open end. The capsule body is designed to be embraced by the annular constrictioll -when the parts of the cap~ule are fitted together. This allegedly results in a good fit of the cap of the capsule on the body thereof.
In another capsule, 3uch ~8 i~ shown in U.S. Patent
2, 718, 980, the capsule cap ha~ on its inside an annular projection and an annular groove. The cap~ule body is also provided a~djacent to its opening with an annular projection and an annular groove. A
reliable ~eal between the cap and body of the capsule is allegedly en~ured in that the projection and groove of one part of the capsule lS snap into the groove and projection of the other cap~ule part when these parts are pu~hed one into the other.
Both the capsule cap and the capsule body of the capsule described in the German Patent Specification l, 536, 219 are formed with an annular constriction. When the two part~ of the capsule are fitted one into the other, the convex annular bead formod on the inside of the cap~ule cap in conjunction ~vith the constriction enters the annular constriction of the capsule body., Cap~ule~ for containing medicament~ are generally made today from hard gelatin in a dipping proce~s. In thi~ process, :,. ' ' ' ~4~ :~
.~ . .
, ~ 455~7 properly de~igned pinY are dipped into an atlueous solution of gelatin and are subsequently ~ithdrawn from the gelatin solution. When the gelatin ha~ dried on the pin, the gelatin body is stripped from the pin and the resulting cap~ule part is cut to the desired length.
In thi~ practice it has been found that annular con~ex projections or concave recesses on the pin render the stripping of the gelatin body more difficult, Be~ides, it i8 almost impos~ible to obtain an airtight seal between the capsule cap and the rim of the capsule body when capsule parts aré fitted together. Thi~ is due to the length tolerances of the capsule parts, particularly to the different di~tances between the rim and the annular rece~ of the capsule body. For a reliably fitting joint, the mating annular concave reces~es or convex projection~ mu~t interengage although this does not en~ure an airtight szal, SUMMA.RY OF THE INVENTION
It i~ an object of the invention to provide a telescopi~ cap~ule which can be manufactured from gelatin in ~uch a manner that the above-mentioned difficulties are avoided. Beaide~, the capsule part~, regardles~ cf length tolerance~ due to their manufacture, ~hould be adapted to be fitted one into the other in conjunct~on with the filling operation ~o that a reliable ~eal is obtained, which is not broken when . .~. .
the cap0ule~ are packaged, tra~sported and sub~equently treated, e. g., on sealing machine3, and ~rhiFh i~ airtight. Thia iB accompli~hed ., ,, - , ' j~ 1139 P/2 CA -2-~6)4SS47 by providing toothlike projections on the inside overlapping 3urface ~ -of either the body or cap which projection~ bear against the opposed ~urface of the body or cap, a~ the case may be.
When the toothlike projection engage the oppo~ite wall of the - -capsule, the elasticity of the gelatin i~ utilized and the opposite part of the capsule is slightly deformed. The compre~3sion of the toothlike projections prevent~ a pulling apart of the parts of the capsule in the longitudinal direction as well a3 rotation of said parts relative to each other. The toothlike projections need be provided only over part of the periphery of the capsule.
The construction of the invention facilitates, above all, the s~ipping of the capsule parts from the dipping pin compared to cap~ule parts which have a continuous annular recess because the ~tripper~
can better slide over the toothlike rece~es in the dipping pin~ than over concave recessefl.
Another problem has al~o been ~olved by the invention. The parts of previously known capsules tend to ~eparate when the capsules are as~embled a~ter having been ~illed because the a~seinbling of the part~ results in compres~ion of air, which tends to force the parts of the capsules apart. For instance, German Patent Appli~:ation P 22 3Z 236 desc:ribe~ an attempt to prevent compre~sing air within the capsule. ~ -ThiR obviously adver~ely affects the tightnes,~ of such cap~ules. In the capsule~, according to the invention, no air can be compre~ed ~rhich would promote a separation of the parts of the cap~u~e becau~e . .
# 1139 P~2 CA _3_ - - . , . , . . :
when the parts of the capsule are fitted together the air can e~cape between the toothlike projection~ until thP very end of the as~embling operation, when airtightne~s is achieved.
In a preferred embodiment, the toothlike projection~ are provided only on the inside surface of the cap of the capsule. In thi~
case only the dipping pins used to make the cap~ule caps mu~t be provided with corre~ponding toothlike rece~ses and the cap parts can easily be stripped from the dipping pins. If the cap3ule bodie~ were also provided on the out~ide ~vith corre~ponding, outwardly directea, toothlike projections, the dipping pins for the capsule bodies would have to be provided ~1vith corresponding, outwardly directed toothlike projections, Whereas thi~ design is also within the ~cope of the invention, it i8 more difficult in this case to make the dipping pins and to 3trip the capsule bodie~ proided with such teeth from the dipping , .
pins.
As stated above, many of the previously known capsule cap~
were provide~with an inwardly facing, annular convex p~ojection for interengaging with the capsule body. Manufacturers po~sess large `
quantities of properly shaped dipping pins iEor use in the manufacture of such capsule cap~ having concave reces3es. These dipping pins can be u~ed to make the capsules according to the pre~ent invention if toothlike reces~es are formed in the concave, recesses of the dipping pins for the cap part~. According to a further feature of the invention, the toothlike projections of the capsule caps are provided on the z5 in ide of a oontinuous peripheral convex projection. ~ -7~ 1139 P/2 CA 4_ S59~7 DETAILED DESCRIPTION
An embodiment o~ the invention will now be described more ~ully with reference to the drawings.
Fig. 1 shows a capsule ~itted together.
Fig. 2 is a transverse sectional view taken on line A-A in Fig. 1.
Fig. 3 is an enlarged ~iew showing the toothllke pro~ec-tions as seen from the inside Or the capsule cap.
Figs. 4 and 5 are transverse sectional views taken o~
lines B-B and C-C in Fig. 3.
Fig. 6 shows a modi~ication of the capsule ~ap, partly broken away.
Fig. 1 shows a capsule 1, which c~mprises a capsule body ~:
2 and a capsule cap 3. At their open ends, the capsule cap and the capsule body 2 terminate in rims 8 and 73 respectivelyO
The ¢losed ends Or the two parts are designated 9 and 11~ res~
pectively, and are spherically shaped. Other end shapes may also .
be used. The capsule cap has an inside sur~ace 5 and the capsule body has an_outside sur~ace 6.
AdJacent to the body portion Bl which is overlapped by the capsule cap ~, the latter has an annular portion ~2, which is ~ormed with inwardly directed, toothlike proJecSions 10, the longitudinal axes o~ which are substantially parallel to the center line o~ the capsule cap 3.
When the capsule body 2 is ~ibted into the capsule cap 3, the ~lm 7 Or the pla1n capsule body 2 slides past thc f~ P ~2.~h~ ~ ~
..
1139 P/2 CA _5_ . . .
.. . .. . .
~45~
capsule body 2 can be pushed into the capsule cap 3 until the rim 7 engages the inside ~urface of the closed end 9 of the capsule cap 3.
It is apparent that thi~ re ult~ in an airtight peripheral seal at lZ between the rim 7 of the cap6ule body 2 and the in~ide surface 5 of the capsule cap 3. Because the capsule according to the invention has no annular concave rece~sea or convex projection~ which mu3t interengage to seal the capsule, the length tolerance~ which are inevitable in the manufacture of any such capsule will not be significant.
The airtight seal 12 bétween the capsule body 2 and the capsule cap 3 0 i9 relatively independent of the distsnce between the annular portion B2 of the capsule cap 3 and the rim 7 of the capsule body.
A reliable joint between the cap3ule cap 3 and the capsule body 2 is provided in that the toothlike projections lO on the inside surface of the cap ule cap 3 engage the outside surface 6 of the capsule body in the portion Bl. It has been found that the engaging force~ are ~ufficiently strong to prevent an opening of the cap~ule 1 when the same i~ packaged and when the packaged cap3ules are handled. Fig. 2 show~
the toothlike projection~ lO on the irlside surface 5 of the capsule cap 3.
These projections are distributed around the periphery of the inside Z0 surface S of the capsule cap 3 and engage the outside ~urface 6 of the cap~ule body 2 80 that the surface 6 is ~lightly deformed, as is 3hown in Fig. 2.
From Fig. 3, two oblique side ~all~ 13, 14 are apparent, ~vhich are connected by an intermediate portion 15. Alternatively, the , # 1139 P/2 CA -6-, - : ~, -~0~5547 side faces 13 and 14 could directly intersect 80 that there i~ no portion 15. The angle ~7 between the lateral ~ide walls 13 and 14 should be at lea~t about 120 and preferably at lea~t 150.
Particularly desirable re~ults will be obtained if the angle of elevation oC, a~ i9 shown in Fig. 5, i8 not in exce88 of about 4û~
preferably not in exces6 of 20.
The ~elected angles are ~o large (~5 ) or 80 ~mall (ot:~ ) becau~e the slope of the teeth should be as gentle as possible ~o that .
the cap~ule caps can easily be stripped from the dipping pins.
Be~ide~, the u~e of ~uch gently-~loped teeth eliminate~ the f~rmation ~ ;
of air bubble~ between the dipping pin and the cap~ule cap during the dipping operation. The air disposed between the gently-~loped teeth can easily escape during the dipping operation, For the ~ame reason, ~pace~ 16 are preferably provided between peripherally adjacent toothlike projection~ l~ 5D that there will be no sharp polnts between adjacent teeth. Sharp point~ render stripping of tt~è capsule part~ from the dipping pin~ and the escape of air more difficult. Be~ide~, when the cap~ule parts are fitted together the wall material of said part~ can ea~ily deform an arch adjacent to the Ypaces 16 ~o that the~e portions contribute to a firm engagement of the toothlike proiections and the latter ensure a reliable retention in spite of their flat ~hape.
# 1139 P/2 CA _7_ ' ~5S~7 The toothlike projections 10 are pre~erably provlded in a number that can be divided by eight and at lea~t by four. The fewer teeth are used, the larger may be the width o~ sald teeth in the peripheral direction. Fewer teeth ~Yill also reduce the ~ormation o~ air bubbles and will facilitS~te the penetration o~ the liquid gelatin between the teeth o~ the dipping pins. The use o~ teeth in a number which can be divLded by four or ei~ht :~
teeth is desirable because the teeth can be rormed on the dipping pins ~ixed on pin bars in this case by special tools which can laterally engage the dippin~ pins rrom opposite sides in two successive steps the positlons Or which are o~fset 90.
Instead o~ providing the toothlike proJections 10 throughout the periphery Or the inside surrace 5 o~ the capsule cap ~, only part o~ the perlphery could be pro~ided with tooth- .
like pro~ections 10.
It is appare~t rrom the above that the ln~entlon permi~s the manuracture of a telesoopio capsule which has a rellable ~oink. It is also apparent that an airtight seal between the capsule body and the capsule cap can be provided even ir the dimensional stability Or the indivldual capsule parts does not meet particularly close tolerances. This is an extraordinary advantage Or this capsule because its manufacture is much simpli-~ied and many less reJects must be discarded than in the pre~lous practice. The Joint between the capsu}e body and the capsule cap ~s due to the engagement Or ~he tooth~like proJections rather than to an lnterengagement o~ annular conca~e recesses and convex ~ -pro~ectlons. For th~s reason the capsule body can always be pushed lnto the capsule cap to such an extent that an # 1139 P/2 CA -8-~4559~7 :
airtight seal i8 established between the rim of ~the capsule body and the inside surface of the cap. The toothlike projections hold the inter-fitting capsule parta against being pulled apart in the longitudinal direction and against relative rotation.
Within the scope of the invention the expression "toothlike projection3" not only includes projections which are more or leY3 pointed or cornered like teeth but include~ alao projection~ which are rounded projection~ of any ~hape whatever.
Fig. 6 shows a continuous peripheral inwardly ~acing convex pro~ection 17. The toothlike pro~ectlons lO are provided on the lnside of this conYex pro~ection 17.
.
~ ' ' .
- # 1139 P/2 CA _g : ' ' ~ " ' , . ... ~ . . ..... . . . . . . . . . . . . . . . . . .............................. .
reliable ~eal between the cap and body of the capsule is allegedly en~ured in that the projection and groove of one part of the capsule lS snap into the groove and projection of the other cap~ule part when these parts are pu~hed one into the other.
Both the capsule cap and the capsule body of the capsule described in the German Patent Specification l, 536, 219 are formed with an annular constriction. When the two part~ of the capsule are fitted one into the other, the convex annular bead formod on the inside of the cap~ule cap in conjunction ~vith the constriction enters the annular constriction of the capsule body., Cap~ule~ for containing medicament~ are generally made today from hard gelatin in a dipping proce~s. In thi~ process, :,. ' ' ' ~4~ :~
.~ . .
, ~ 455~7 properly de~igned pinY are dipped into an atlueous solution of gelatin and are subsequently ~ithdrawn from the gelatin solution. When the gelatin ha~ dried on the pin, the gelatin body is stripped from the pin and the resulting cap~ule part is cut to the desired length.
In thi~ practice it has been found that annular con~ex projections or concave recesses on the pin render the stripping of the gelatin body more difficult, Be~ides, it i8 almost impos~ible to obtain an airtight seal between the capsule cap and the rim of the capsule body when capsule parts aré fitted together. Thi~ is due to the length tolerances of the capsule parts, particularly to the different di~tances between the rim and the annular rece~ of the capsule body. For a reliably fitting joint, the mating annular concave reces~es or convex projection~ mu~t interengage although this does not en~ure an airtight szal, SUMMA.RY OF THE INVENTION
It i~ an object of the invention to provide a telescopi~ cap~ule which can be manufactured from gelatin in ~uch a manner that the above-mentioned difficulties are avoided. Beaide~, the capsule part~, regardles~ cf length tolerance~ due to their manufacture, ~hould be adapted to be fitted one into the other in conjunct~on with the filling operation ~o that a reliable ~eal is obtained, which is not broken when . .~. .
the cap0ule~ are packaged, tra~sported and sub~equently treated, e. g., on sealing machine3, and ~rhiFh i~ airtight. Thia iB accompli~hed ., ,, - , ' j~ 1139 P/2 CA -2-~6)4SS47 by providing toothlike projections on the inside overlapping 3urface ~ -of either the body or cap which projection~ bear against the opposed ~urface of the body or cap, a~ the case may be.
When the toothlike projection engage the oppo~ite wall of the - -capsule, the elasticity of the gelatin i~ utilized and the opposite part of the capsule is slightly deformed. The compre~3sion of the toothlike projections prevent~ a pulling apart of the parts of the capsule in the longitudinal direction as well a3 rotation of said parts relative to each other. The toothlike projections need be provided only over part of the periphery of the capsule.
The construction of the invention facilitates, above all, the s~ipping of the capsule parts from the dipping pin compared to cap~ule parts which have a continuous annular recess because the ~tripper~
can better slide over the toothlike rece~es in the dipping pin~ than over concave recessefl.
Another problem has al~o been ~olved by the invention. The parts of previously known capsules tend to ~eparate when the capsules are as~embled a~ter having been ~illed because the a~seinbling of the part~ results in compres~ion of air, which tends to force the parts of the capsules apart. For instance, German Patent Appli~:ation P 22 3Z 236 desc:ribe~ an attempt to prevent compre~sing air within the capsule. ~ -ThiR obviously adver~ely affects the tightnes,~ of such cap~ules. In the capsule~, according to the invention, no air can be compre~ed ~rhich would promote a separation of the parts of the cap~u~e becau~e . .
# 1139 P~2 CA _3_ - - . , . , . . :
when the parts of the capsule are fitted together the air can e~cape between the toothlike projection~ until thP very end of the as~embling operation, when airtightne~s is achieved.
In a preferred embodiment, the toothlike projection~ are provided only on the inside surface of the cap of the capsule. In thi~
case only the dipping pins used to make the cap~ule caps mu~t be provided with corre~ponding toothlike rece~ses and the cap parts can easily be stripped from the dipping pins. If the cap3ule bodie~ were also provided on the out~ide ~vith corre~ponding, outwardly directea, toothlike projections, the dipping pins for the capsule bodies would have to be provided ~1vith corresponding, outwardly directed toothlike projections, Whereas thi~ design is also within the ~cope of the invention, it i8 more difficult in this case to make the dipping pins and to 3trip the capsule bodie~ proided with such teeth from the dipping , .
pins.
As stated above, many of the previously known capsule cap~
were provide~with an inwardly facing, annular convex p~ojection for interengaging with the capsule body. Manufacturers po~sess large `
quantities of properly shaped dipping pins iEor use in the manufacture of such capsule cap~ having concave reces3es. These dipping pins can be u~ed to make the capsules according to the pre~ent invention if toothlike reces~es are formed in the concave, recesses of the dipping pins for the cap part~. According to a further feature of the invention, the toothlike projections of the capsule caps are provided on the z5 in ide of a oontinuous peripheral convex projection. ~ -7~ 1139 P/2 CA 4_ S59~7 DETAILED DESCRIPTION
An embodiment o~ the invention will now be described more ~ully with reference to the drawings.
Fig. 1 shows a capsule ~itted together.
Fig. 2 is a transverse sectional view taken on line A-A in Fig. 1.
Fig. 3 is an enlarged ~iew showing the toothllke pro~ec-tions as seen from the inside Or the capsule cap.
Figs. 4 and 5 are transverse sectional views taken o~
lines B-B and C-C in Fig. 3.
Fig. 6 shows a modi~ication of the capsule ~ap, partly broken away.
Fig. 1 shows a capsule 1, which c~mprises a capsule body ~:
2 and a capsule cap 3. At their open ends, the capsule cap and the capsule body 2 terminate in rims 8 and 73 respectivelyO
The ¢losed ends Or the two parts are designated 9 and 11~ res~
pectively, and are spherically shaped. Other end shapes may also .
be used. The capsule cap has an inside sur~ace 5 and the capsule body has an_outside sur~ace 6.
AdJacent to the body portion Bl which is overlapped by the capsule cap ~, the latter has an annular portion ~2, which is ~ormed with inwardly directed, toothlike proJecSions 10, the longitudinal axes o~ which are substantially parallel to the center line o~ the capsule cap 3.
When the capsule body 2 is ~ibted into the capsule cap 3, the ~lm 7 Or the pla1n capsule body 2 slides past thc f~ P ~2.~h~ ~ ~
..
1139 P/2 CA _5_ . . .
.. . .. . .
~45~
capsule body 2 can be pushed into the capsule cap 3 until the rim 7 engages the inside ~urface of the closed end 9 of the capsule cap 3.
It is apparent that thi~ re ult~ in an airtight peripheral seal at lZ between the rim 7 of the cap6ule body 2 and the in~ide surface 5 of the capsule cap 3. Because the capsule according to the invention has no annular concave rece~sea or convex projection~ which mu3t interengage to seal the capsule, the length tolerance~ which are inevitable in the manufacture of any such capsule will not be significant.
The airtight seal 12 bétween the capsule body 2 and the capsule cap 3 0 i9 relatively independent of the distsnce between the annular portion B2 of the capsule cap 3 and the rim 7 of the capsule body.
A reliable joint between the cap3ule cap 3 and the capsule body 2 is provided in that the toothlike projections lO on the inside surface of the cap ule cap 3 engage the outside surface 6 of the capsule body in the portion Bl. It has been found that the engaging force~ are ~ufficiently strong to prevent an opening of the cap~ule 1 when the same i~ packaged and when the packaged cap3ules are handled. Fig. 2 show~
the toothlike projection~ lO on the irlside surface 5 of the capsule cap 3.
These projections are distributed around the periphery of the inside Z0 surface S of the capsule cap 3 and engage the outside ~urface 6 of the cap~ule body 2 80 that the surface 6 is ~lightly deformed, as is 3hown in Fig. 2.
From Fig. 3, two oblique side ~all~ 13, 14 are apparent, ~vhich are connected by an intermediate portion 15. Alternatively, the , # 1139 P/2 CA -6-, - : ~, -~0~5547 side faces 13 and 14 could directly intersect 80 that there i~ no portion 15. The angle ~7 between the lateral ~ide walls 13 and 14 should be at lea~t about 120 and preferably at lea~t 150.
Particularly desirable re~ults will be obtained if the angle of elevation oC, a~ i9 shown in Fig. 5, i8 not in exce88 of about 4û~
preferably not in exces6 of 20.
The ~elected angles are ~o large (~5 ) or 80 ~mall (ot:~ ) becau~e the slope of the teeth should be as gentle as possible ~o that .
the cap~ule caps can easily be stripped from the dipping pins.
Be~ide~, the u~e of ~uch gently-~loped teeth eliminate~ the f~rmation ~ ;
of air bubble~ between the dipping pin and the cap~ule cap during the dipping operation. The air disposed between the gently-~loped teeth can easily escape during the dipping operation, For the ~ame reason, ~pace~ 16 are preferably provided between peripherally adjacent toothlike projection~ l~ 5D that there will be no sharp polnts between adjacent teeth. Sharp point~ render stripping of tt~è capsule part~ from the dipping pin~ and the escape of air more difficult. Be~ide~, when the cap~ule parts are fitted together the wall material of said part~ can ea~ily deform an arch adjacent to the Ypaces 16 ~o that the~e portions contribute to a firm engagement of the toothlike proiections and the latter ensure a reliable retention in spite of their flat ~hape.
# 1139 P/2 CA _7_ ' ~5S~7 The toothlike projections 10 are pre~erably provlded in a number that can be divided by eight and at lea~t by four. The fewer teeth are used, the larger may be the width o~ sald teeth in the peripheral direction. Fewer teeth ~Yill also reduce the ~ormation o~ air bubbles and will facilitS~te the penetration o~ the liquid gelatin between the teeth o~ the dipping pins. The use o~ teeth in a number which can be divLded by four or ei~ht :~
teeth is desirable because the teeth can be rormed on the dipping pins ~ixed on pin bars in this case by special tools which can laterally engage the dippin~ pins rrom opposite sides in two successive steps the positlons Or which are o~fset 90.
Instead o~ providing the toothlike proJections 10 throughout the periphery Or the inside surrace 5 o~ the capsule cap ~, only part o~ the perlphery could be pro~ided with tooth- .
like pro~ections 10.
It is appare~t rrom the above that the ln~entlon permi~s the manuracture of a telesoopio capsule which has a rellable ~oink. It is also apparent that an airtight seal between the capsule body and the capsule cap can be provided even ir the dimensional stability Or the indivldual capsule parts does not meet particularly close tolerances. This is an extraordinary advantage Or this capsule because its manufacture is much simpli-~ied and many less reJects must be discarded than in the pre~lous practice. The Joint between the capsu}e body and the capsule cap ~s due to the engagement Or ~he tooth~like proJections rather than to an lnterengagement o~ annular conca~e recesses and convex ~ -pro~ectlons. For th~s reason the capsule body can always be pushed lnto the capsule cap to such an extent that an # 1139 P/2 CA -8-~4559~7 :
airtight seal i8 established between the rim of ~the capsule body and the inside surface of the cap. The toothlike projections hold the inter-fitting capsule parta against being pulled apart in the longitudinal direction and against relative rotation.
Within the scope of the invention the expression "toothlike projection3" not only includes projections which are more or leY3 pointed or cornered like teeth but include~ alao projection~ which are rounded projection~ of any ~hape whatever.
Fig. 6 shows a continuous peripheral inwardly ~acing convex pro~ection 17. The toothlike pro~ectlons lO are provided on the lnside of this conYex pro~ection 17.
.
~ ' ' .
- # 1139 P/2 CA _g : ' ' ~ " ' , . ... ~ . . ..... . . . . . . . . . . . . . . . . . .............................. .
Claims (9)
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. A gelatin capsule for receiving a filling comprising, in combination, a body having a closed end, a substantially cylindrical wall, and an open end; a telescoping cap having a closed end, a substantially cylindrical wall, and an open end for receiving the open end of the body with cap wall telescopically overlapping the body wall; said cap wall including a plurality of tooth-like spaced projections in a continuous row about the entire circumference of the cap wall for surrounding, engaging and locally deforming the wall of the body received in and overlapped thereby to provide resistance to relative movement between the body and the cap.
2. A gelatin capsule according to Claim 1 wherein said tooth-like projections are provided on the interior of the cap wall.
3. A gelatin capsule according to Claim 2 wherein said cap has an inwardly directed annular convex projection on which said tooth-like projections are disposed.
4. A gelatin capsule according to Claims 1, 2 or 3 wherein the number of said tooth-like projections is a multiple of four.
5. A gelatin capsule according to Claims 1, 2 or 3 wherein the body wall has a rim at its open end for sealing engagement with the cap wall adjacent its closed end to provide an air tight seal between the body and the cap.
6. A gelatin capsule according to Claims 1, 2 or 3 wherein the tooth-like projections have side walls sloping gently both in the lateral and longitudinal directions of the cap.
7. A gelatin capsule according to Claims 1, 2 or 3 wherein the body wall has a rim at its open end for sealing engagement with the cap wall adjacent its closed end to provide an air tight seal between the body and the cap; the tooth-like projections having side walls sloping gently both in the lateral and longitudinal directions of the cap.
8. A gelatin capsule according to Claims 1, 2 or 3 wherein the tooth-like projections have side walls sloping gently both in the lateral and longitudinal directions of the cap; the angle between opposed laterally-sloping side walls of each tooth-like projection being at least 120° and the angle of elevation of the longitudinal side walls of each tooth-like projection being less than 41°.
9. A gelatin capsule according to Claims 1, 2 or 3 wherein the tooth-like projections have side walls sloping gently both in the lateral and longitudinal directions of the cap;
the angle between opposed laterally-sloping side walls of each tooth-like projection being at least 120° and the angle of elevation of the longitudinal side walls of each tooth-like projection being less than 41°; the body wall having a rim at its open end for sealing engagement with the cap wall adjacent its closed end to provide an air tight seal between the body and the cap.
the angle between opposed laterally-sloping side walls of each tooth-like projection being at least 120° and the angle of elevation of the longitudinal side walls of each tooth-like projection being less than 41°; the body wall having a rim at its open end for sealing engagement with the cap wall adjacent its closed end to provide an air tight seal between the body and the cap.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19742428397 DE2428397C3 (en) | 1974-06-12 | 1974-06-12 | Two-part capsule made of hard gelatine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1045547A true CA1045547A (en) | 1979-01-02 |
Family
ID=5917962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA229,089A Expired CA1045547A (en) | 1974-06-12 | 1975-06-11 | Capsule, especially for medicaments |
Country Status (8)
| Country | Link |
|---|---|
| JP (2) | JPS5138414A (en) |
| BE (1) | BE829902A (en) |
| CA (1) | CA1045547A (en) |
| DE (1) | DE2428397C3 (en) |
| ES (1) | ES213111Y (en) |
| FR (1) | FR2274275A1 (en) |
| GB (1) | GB1496737A (en) |
| IT (1) | IT1032881B (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE27546T1 (en) * | 1982-10-29 | 1987-06-15 | Warner Lambert Co | COUNTERFEIT-PROOF CAPSULES. |
| CH664938A5 (en) * | 1983-10-20 | 1988-04-15 | Warner Lambert Co | PRINTED ARTICLES. |
| JPH0774149B2 (en) * | 1991-12-27 | 1995-08-09 | 藤本製薬株式会社 | Hard gelatin capsule |
| US6245350B1 (en) | 1994-12-16 | 2001-06-12 | Warner-Lambert Company | Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process |
| DE69518006T2 (en) * | 1994-12-16 | 2000-12-21 | Warner Lambert Co | METHOD FOR ENCLOSURE TABLETS IN A CAPSULE AND SOLID DOSAGE FORMS AVAILABLE BY THIS METHOD |
| KR0124764Y1 (en) * | 1995-09-23 | 1998-09-15 | 양주환 | Medical capsule |
| US7163693B1 (en) | 1999-07-30 | 2007-01-16 | Smithkline Beecham Plc | Multi-component pharmaceutical dosage form |
| US7883721B2 (en) | 2001-01-30 | 2011-02-08 | Smithkline Beecham Limited | Pharmaceutical formulation |
| US7842308B2 (en) | 2001-01-30 | 2010-11-30 | Smithkline Beecham Limited | Pharmaceutical formulation |
| GB0102342D0 (en) | 2001-01-30 | 2001-03-14 | Smithkline Beecham Plc | Pharmaceutical formulation |
| TW200526274A (en) | 2003-07-21 | 2005-08-16 | Smithkline Beecham Plc | Pharmaceutical formulations |
| TW200539903A (en) | 2004-03-12 | 2005-12-16 | Smithkline Beecham Plc | Pharmaceutical formulations |
| JP5190515B2 (en) | 2007-10-15 | 2013-04-24 | カプスゲル・ベルギウム・ナムローゼ・フェンノートシャップ | Method and apparatus for producing a filled linker |
| CN101827572A (en) | 2007-10-15 | 2010-09-08 | 葛兰素集团有限公司 | Paneled capsule shells for release of pharmaceutical compositions |
| DE102014019214A1 (en) | 2014-12-23 | 2016-06-23 | Bio-Tec Biologische Naturverpackungen Gmbh & Co.Kg | Process for the production of molded parts |
| CN110471318B (en) * | 2019-06-26 | 2022-05-10 | 康美药业股份有限公司 | Intelligent control system of pharmacy heating furnace |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5032797Y2 (en) * | 1971-06-15 | 1975-09-25 | ||
| JPS5317881Y2 (en) * | 1974-09-26 | 1978-05-13 |
-
1974
- 1974-06-12 DE DE19742428397 patent/DE2428397C3/en not_active Expired
-
1975
- 1975-05-14 IT IT6823575A patent/IT1032881B/en active
- 1975-06-05 BE BE157050A patent/BE829902A/en not_active IP Right Cessation
- 1975-06-09 FR FR7517871A patent/FR2274275A1/en active Granted
- 1975-06-10 GB GB2483475A patent/GB1496737A/en not_active Expired
- 1975-06-11 CA CA229,089A patent/CA1045547A/en not_active Expired
- 1975-06-12 JP JP7025275A patent/JPS5138414A/en active Pending
- 1975-06-12 ES ES1975213111U patent/ES213111Y/en not_active Expired
-
1981
- 1981-02-26 JP JP2533881U patent/JPS56138634U/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE2428397C3 (en) | 1978-05-18 |
| DE2428397A1 (en) | 1976-02-26 |
| ES213111U (en) | 1976-06-16 |
| BE829902A (en) | 1975-12-05 |
| FR2274275B1 (en) | 1982-04-09 |
| ES213111Y (en) | 1976-11-01 |
| DE2428397B2 (en) | 1977-09-15 |
| GB1496737A (en) | 1977-12-30 |
| JPS56138634U (en) | 1981-10-20 |
| JPS5138414A (en) | 1976-03-31 |
| FR2274275A1 (en) | 1976-01-09 |
| IT1032881B (en) | 1979-06-20 |
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