CA1042003A - Analogues of prostanoic acids not occurring in nature and process for preparing them - Google Patents

Analogues of prostanoic acids not occurring in nature and process for preparing them

Info

Publication number
CA1042003A
CA1042003A CA220,062A CA220062A CA1042003A CA 1042003 A CA1042003 A CA 1042003A CA 220062 A CA220062 A CA 220062A CA 1042003 A CA1042003 A CA 1042003A
Authority
CA
Canada
Prior art keywords
formula
dimethyl
trans
compound
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA220,062A
Other languages
English (en)
French (fr)
Inventor
Milos Babej
Wilhelm Bartmann
Gerhard Beck
Ulrich Lerch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2407186A external-priority patent/DE2407186C2/de
Priority claimed from DE19742445526 external-priority patent/DE2445526A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of CA1042003A publication Critical patent/CA1042003A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/06Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA220,062A 1974-02-15 1975-02-13 Analogues of prostanoic acids not occurring in nature and process for preparing them Expired CA1042003A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2407186A DE2407186C2 (de) 1974-02-15 1974-02-15 Neue, natürlich nicht vorkommende Analoga von Prostansäuren und Verfahren zu ihrer Herstellung, sowie diese Analoga von Prostansäuren enthaltende Arzneimittel
DE19742445526 DE2445526A1 (de) 1974-09-24 1974-09-24 Bronchodilatorisch wirksame arzneimittel

Publications (1)

Publication Number Publication Date
CA1042003A true CA1042003A (en) 1978-11-07

Family

ID=25766631

Family Applications (1)

Application Number Title Priority Date Filing Date
CA220,062A Expired CA1042003A (en) 1974-02-15 1975-02-13 Analogues of prostanoic acids not occurring in nature and process for preparing them

Country Status (13)

Country Link
JP (1) JPS5854139B2 (zh)
CA (1) CA1042003A (zh)
CH (1) CH617675A5 (zh)
DK (1) DK55575A (zh)
ES (2) ES434590A1 (zh)
FR (1) FR2261004B1 (zh)
GB (1) GB1507501A (zh)
HU (1) HU174323B (zh)
IE (1) IE41407B1 (zh)
IL (1) IL46615A0 (zh)
LU (1) LU71837A1 (zh)
NL (1) NL7501560A (zh)
SE (1) SE7501653L (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4387241A (en) * 1974-11-01 1983-06-07 American Cyanamid Company Novel 16-aryloxy-17,18,19,20-tetranorprostanoic acids and derivatives
US4032561A (en) * 1975-05-27 1977-06-28 The Upjohn Company 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF1.sub.α compounds
ZA771725B (en) * 1976-04-21 1978-02-22 Upjohn Co Ayal prostaglandin analogs
US4228296A (en) * 1979-01-24 1980-10-14 American Cyanamid Company Novel 16-aryloxy-17,18,19,20-tetranorprostanoic acids and derivatives

Also Published As

Publication number Publication date
JPS50123644A (zh) 1975-09-29
IE41407L (en) 1975-08-15
JPS5854139B2 (ja) 1983-12-02
FR2261004B1 (zh) 1978-07-21
DK55575A (zh) 1975-10-13
LU71837A1 (zh) 1977-01-05
FR2261004A1 (zh) 1975-09-12
SE7501653L (zh) 1975-08-18
AU7817775A (en) 1976-08-19
GB1507501A (en) 1978-04-19
ES434590A1 (es) 1977-04-01
CH617675A5 (en) 1980-06-13
IL46615A0 (en) 1975-04-25
ES452901A1 (es) 1977-11-01
NL7501560A (nl) 1975-08-19
HU174323B (hu) 1979-12-28
IE41407B1 (en) 1980-01-02

Similar Documents

Publication Publication Date Title
DE2902442A1 (de) 9-deoxy-9a-methylen-isostere von pgi tief 2 , verfahren zu ihrer herstellung und sie enthaltende pharmazeutische und veterinaermedizinische mittel
CA1042003A (en) Analogues of prostanoic acids not occurring in nature and process for preparing them
US3881017A (en) 9-Thiaprostaglandin compositions
US3957794A (en) 3-Amino-2,3,3a,6,7,7a-hexahydro-thieno[3,2-b]pyridin-(4H)5-one
US4078083A (en) Novel prostanoic acids
US4098815A (en) Novel analogues of prostanoic acids not occurring in nature
US4174458A (en) Novel analogues of prostanoic acids not occurring in nature
US4024181A (en) Analogues of prostanoic acids
US4806668A (en) Process for the production of 9beta-chloroprostaglandins
US4053467A (en) Prostaglandin derivatives
EP0001270A1 (de) Neue Prostacyclin-Analoga, Verfahren zu ihrer Herstellung und ihre Verwendung bei der Behandlung von Herzkreislauf-Krankheiten
US4091015A (en) 15-Substituted prostanoic acids
US3801623A (en) Cyclopentanone derivatives
US4022821A (en) 15-Substituted prostanoic acid
US4062783A (en) 15-Ethynyl substituted prostanoic acids
DE2407186C2 (de) Neue, natürlich nicht vorkommende Analoga von Prostansäuren und Verfahren zu ihrer Herstellung, sowie diese Analoga von Prostansäuren enthaltende Arzneimittel
US3989724A (en) Tetrahydropyran-2-ols
Cantrell Reactivity of photochemically excited 3-acylthiophenes, 3-acylfurans, and the formylthiophenes and furans
US3682964A (en) Spiro benzocyclane acetic acid compounds
US4033985A (en) 15-Substituted prostanoic acid
US3718667A (en) 2,3-disubstituted levulinaldehyde compounds
DD140745A5 (de) Verfahren zur herstellung von neuen prostaglandinen
US4059701A (en) 15-Substituted prostanoic acids for treating bronchial spasm
US4296121A (en) Novel prostaglandin derivatives of the Δ2-PGF2 and Δ2-PGE2 series and process for their manufacture
US3992437A (en) Polyhydrophenanthrene derivatives