CA1035772A - Process for preparing 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-pyrimidine - Google Patents
Process for preparing 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-pyrimidineInfo
- Publication number
- CA1035772A CA1035772A CA168,071A CA168071A CA1035772A CA 1035772 A CA1035772 A CA 1035772A CA 168071 A CA168071 A CA 168071A CA 1035772 A CA1035772 A CA 1035772A
- Authority
- CA
- Canada
- Prior art keywords
- trimethoxybenzyl
- diamino
- pyrimidine
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU1211/72A YU34880B (en) | 1972-05-08 | 1972-05-08 | Process for preparing 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-pyrimidine |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1035772A true CA1035772A (en) | 1978-08-01 |
Family
ID=25553232
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA168,071A Expired CA1035772A (en) | 1972-05-08 | 1973-04-06 | Process for preparing 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-pyrimidine |
Country Status (7)
Country | Link |
---|---|
AT (1) | AT326665B (en) |
CA (1) | CA1035772A (en) |
CH (1) | CH592635A5 (en) |
DE (1) | DE2309760A1 (en) |
FR (1) | FR2183769B1 (en) |
GB (1) | GB1420842A (en) |
YU (1) | YU34880B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1138146B (en) * | 1981-08-11 | 1986-09-17 | Proter Spa | PROCESS FOR THE PRODUCTION OF 2,4-DIAMINE- (3,5-DIMETHOXY-4-METOS SIETOXY-BENZYL) -PYRIMIDINE |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1459417A (en) * | 1964-11-12 | 1966-04-29 | Hoffmann La Roche | Process for the preparation of pyrimidine derivatives |
DE2165362A1 (en) * | 1970-12-29 | 1972-07-27 | Nisshin Flour Milling Co. Ltd., Tokio | 5-benzyl-2,4-diaminopyrimidines prepn - by 5-stage process from benzaldehydes and alkyl cyanoacetates |
-
1972
- 1972-05-08 YU YU1211/72A patent/YU34880B/en unknown
-
1973
- 1973-02-15 AT AT133873A patent/AT326665B/en not_active IP Right Cessation
- 1973-02-19 CH CH237073A patent/CH592635A5/xx not_active IP Right Cessation
- 1973-02-20 GB GB837973A patent/GB1420842A/en not_active Expired
- 1973-02-27 DE DE19732309760 patent/DE2309760A1/en active Pending
- 1973-04-06 CA CA168,071A patent/CA1035772A/en not_active Expired
- 1973-05-04 FR FR7316041A patent/FR2183769B1/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
AT326665B (en) | 1975-12-29 |
DE2309760A1 (en) | 1973-11-22 |
YU34880B (en) | 1980-04-30 |
GB1420842A (en) | 1976-01-14 |
YU121172A (en) | 1979-10-31 |
ATA133873A (en) | 1975-03-15 |
CH592635A5 (en) | 1977-10-31 |
FR2183769B1 (en) | 1978-02-10 |
FR2183769A1 (en) | 1973-12-21 |
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