CA1033731A - Process for preparing 1-oxo-1h-6-hydroxypyrimido (1,2-a)quinoline-2-carboxylic acids and derivatives - Google Patents

Process for preparing 1-oxo-1h-6-hydroxypyrimido (1,2-a)quinoline-2-carboxylic acids and derivatives

Info

Publication number
CA1033731A
CA1033731A CA222,180A CA222180A CA1033731A CA 1033731 A CA1033731 A CA 1033731A CA 222180 A CA222180 A CA 222180A CA 1033731 A CA1033731 A CA 1033731A
Authority
CA
Canada
Prior art keywords
hydroxypyrimido
quinoline
oxo
derivatives
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA222,180A
Other languages
English (en)
French (fr)
Inventor
Saul B. Kadin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Application granted granted Critical
Publication of CA1033731A publication Critical patent/CA1033731A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA222,180A 1974-04-01 1975-03-17 Process for preparing 1-oxo-1h-6-hydroxypyrimido (1,2-a)quinoline-2-carboxylic acids and derivatives Expired CA1033731A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45679774A 1974-04-01 1974-04-01
US54722775A 1975-02-05 1975-02-05
US55496675A 1975-03-03 1975-03-03

Publications (1)

Publication Number Publication Date
CA1033731A true CA1033731A (en) 1978-06-27

Family

ID=27412681

Family Applications (1)

Application Number Title Priority Date Filing Date
CA222,180A Expired CA1033731A (en) 1974-04-01 1975-03-17 Process for preparing 1-oxo-1h-6-hydroxypyrimido (1,2-a)quinoline-2-carboxylic acids and derivatives

Country Status (14)

Country Link
JP (1) JPS5427360B2 (enExample)
CA (1) CA1033731A (enExample)
DD (1) DD119425A5 (enExample)
DE (1) DE2513930A1 (enExample)
DK (1) DK138743B (enExample)
ES (1) ES436155A1 (enExample)
FI (1) FI750891A7 (enExample)
FR (1) FR2265389B1 (enExample)
GB (1) GB1451423A (enExample)
IE (1) IE40893B1 (enExample)
IL (1) IL46864A0 (enExample)
LU (1) LU72184A1 (enExample)
NL (1) NL7503692A (enExample)
PH (1) PH10464A (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4075343A (en) * 1976-09-13 1978-02-21 Pfizer Inc. Anti-allergenic 5-alkoxyimidazo[1,2-A]quinoline-2-carboxylic acids and derivatives thereof
US4127720A (en) * 1977-09-21 1978-11-28 Bristol-Myers Company Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activity
US4209620A (en) * 1978-06-19 1980-06-24 Bristol-Myers Company Substituted 3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives having antiallergy activity
US4472401A (en) * 1981-11-27 1984-09-18 Roussel Uclaf Pyrimido-quinoxalines having antiallergic properties
US4510143A (en) * 1982-02-17 1985-04-09 Roussel Uclaf Antiallergic pyrimido[1,2-a]quinoxalin-2-carboxylic acid derivatives
AU5533996A (en) * 1996-04-04 1997-10-29 University Of Nebraska Board Of Regents Synthetic triple helix-forming compounds
US6989392B2 (en) 2002-06-18 2006-01-24 Abbott Laboratories 2-Aminoquinolines as melanin concentrating hormone receptor antagonists

Also Published As

Publication number Publication date
IL46864A0 (en) 1975-05-22
FR2265389A1 (enExample) 1975-10-24
IE40893L (en) 1975-10-01
DK138743B (da) 1978-10-23
JPS50140499A (enExample) 1975-11-11
AU7937775A (en) 1976-09-23
DK130475A (enExample) 1975-10-02
NL7503692A (nl) 1975-10-03
IE40893B1 (en) 1979-09-12
FR2265389B1 (enExample) 1978-07-28
DK138743C (enExample) 1979-04-02
GB1451423A (en) 1976-10-06
FI750891A7 (enExample) 1975-10-02
ES436155A1 (es) 1977-02-01
PH10464A (en) 1977-04-25
DE2513930A1 (de) 1975-10-02
LU72184A1 (enExample) 1976-03-02
JPS5427360B2 (enExample) 1979-09-10
DD119425A5 (enExample) 1976-04-20

Similar Documents

Publication Publication Date Title
CA981665A (en) 9-desoxy-prosta-5,9(10),13-trienoic acid derivatives and process for their preparation
CA1027560A (en) Prostenoic acid derivatives and method for preparing same
AU499841B2 (en) 3, 5-bisoxygenated 2(w-halo-3-oxygenated -1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof
AU487426B2 (en) Process for preparing phoshporothioates and phenylphosphonothioates
CA999857A (en) 8,12-diisoprostanoic acid derivatives and process for their preparation
AU477030B2 (en) 6-substituted cholesten derivatives and process for preparing the same
AU487705B2 (en) 1-oxo-1h-6-hydroxypyrimido (1,2-a) quinoline-2-carboxylic acids and derivatives
PT65294A (en) Process for the preparation of 1-oxo-1h-6-substitutedpyrimidio(1,2-a)quinoline-2-carboxylic acids
AU476201B2 (en) METHOD OF PREPARING 4, 4-DIMETHYLDIOXANE-l, 3
ZA776030B (en) New 17-spirosultine derivatives,the corresponding ypsilon-hydroxy acids,process for preparing them and pharmaceutical compositions
AU484454B2 (en) 5:6-benzo-8-pyrone derivatives and process for their preparation
AU493132B2 (en) PROCESS FORTHE PREPARATION OFS-TRIAZOLO (3, 4-b) BENZOTHIAZOLES
AU493765B2 (en) Novel 16-aryloxy-17, 18,19,20-tetranoprostanoic acids and derivatives
AU491389B2 (en) 3, 7-dimethyl-3-hydroxy-6-ocetenenitrile and process for its preparation
AU479472B2 (en) Novel benzylalcohol derivatives and process for preparing same
AU475781B2 (en) Glycerol derivatives and process for preparing the same
AU476247B2 (en) Carbostyril derivatives and process for preparing thesame
AU468302B2 (en) Polyamides and process for preparation thereof
AU484210B2 (en) 1-OXO-1H-6-SUBSTITUTED PYRIMIDO 1, 2-a) QUINOLINE-2-CARBOXYLIC ACIDS ANDA PROCESS FOR THEIR PRODUCTION
AU493283B2 (en) Process for the preparation of 9,11,15-trihydroxy-13,14-dehydro-prostaglandins and new prost-5-en-13-ynoic acid derivatives
AU489936B2 (en) An improved process for the preparation of 3-trichloromethyl-5-chloro-1,2,40thiadiazole
CA1030158A (en) Process for preparing 2,5-dihalo-3-nitrobenzoic acid and derivatives thereof
AU481163B2 (en) Novel prostenoic acid derivatives and method for preparing same
GB1523178A (en) 8-azaprostanoic acid derivatives and process for preparing the same
CA1032871A (en) Acetoxime derivatives and process for preparing the same