CA1028262A - Method for purification and recovery of urokinase - Google Patents

Method for purification and recovery of urokinase

Info

Publication number
CA1028262A
CA1028262A CA217,049A CA217049A CA1028262A CA 1028262 A CA1028262 A CA 1028262A CA 217049 A CA217049 A CA 217049A CA 1028262 A CA1028262 A CA 1028262A
Authority
CA
Canada
Prior art keywords
urokinase
purification
recovery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA217,049A
Other languages
French (fr)
Other versions
CA217049S (en
Inventor
Katuhiro Uriyu
Satoshi Funakoshi
Yahiro Uemura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1002274A external-priority patent/JPS517751B2/ja
Priority claimed from JP1201674A external-priority patent/JPS517752B2/ja
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Application granted granted Critical
Publication of CA1028262A publication Critical patent/CA1028262A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA217,049A 1974-01-22 1974-12-30 Method for purification and recovery of urokinase Expired CA1028262A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1002274A JPS517751B2 (en) 1974-01-22 1974-01-22
JP1201674A JPS517752B2 (en) 1974-01-28 1974-01-28

Publications (1)

Publication Number Publication Date
CA1028262A true CA1028262A (en) 1978-03-21

Family

ID=26345171

Family Applications (1)

Application Number Title Priority Date Filing Date
CA217,049A Expired CA1028262A (en) 1974-01-22 1974-12-30 Method for purification and recovery of urokinase

Country Status (10)

Country Link
AT (1) AT341079B (en)
AU (1) AU474513B2 (en)
CA (1) CA1028262A (en)
CH (1) CH611314A5 (en)
DE (1) DE2502095C3 (en)
ES (1) ES433961A1 (en)
FR (1) FR2258396B1 (en)
GB (1) GB1476092A (en)
IN (1) IN139029B (en)
SE (1) SE434956B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2444465A1 (en) * 1978-12-22 1980-07-18 Green Cross Corp Antithrombotic agent contg. urokinase - produced by maintaining pH neutral or weakly alkaline during each processing step for urokinase prodn.

Also Published As

Publication number Publication date
SE7500629L (en) 1975-07-23
SE434956B (en) 1984-08-27
ES433961A1 (en) 1976-11-16
DE2502095B2 (en) 1978-06-29
CH611314A5 (en) 1979-05-31
IN139029B (en) 1976-04-24
AU474513B2 (en) 1976-07-22
DE2502095A1 (en) 1975-07-24
DE2502095C3 (en) 1979-02-22
AT341079B (en) 1978-01-25
AU7688374A (en) 1976-06-24
ATA43475A (en) 1977-05-15
FR2258396A1 (en) 1975-08-18
GB1476092A (en) 1977-06-10
FR2258396B1 (en) 1977-11-18

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