CA1016945A - 2-amino-4,5-dihydropyridine derivatives - Google Patents

2-amino-4,5-dihydropyridine derivatives

Info

Publication number
CA1016945A
CA1016945A CA177,996A CA177996A CA1016945A CA 1016945 A CA1016945 A CA 1016945A CA 177996 A CA177996 A CA 177996A CA 1016945 A CA1016945 A CA 1016945A
Authority
CA
Canada
Prior art keywords
amino
dihydropyridine derivatives
dihydropyridine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA177,996A
Other languages
English (en)
Other versions
CA177996S (en
Inventor
Kurt Stoepel
Friedrich Bossert
Wulf Vater
Horst Meyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of CA1016945A publication Critical patent/CA1016945A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA177,996A 1972-08-12 1973-08-02 2-amino-4,5-dihydropyridine derivatives Expired CA1016945A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2239815A DE2239815C2 (de) 1972-08-12 1972-08-12 2-Alkylamino-dihydropyridine, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CA1016945A true CA1016945A (en) 1977-09-06

Family

ID=5853453

Family Applications (1)

Application Number Title Priority Date Filing Date
CA177,996A Expired CA1016945A (en) 1972-08-12 1973-08-02 2-amino-4,5-dihydropyridine derivatives

Country Status (29)

Country Link
US (1) US3959292A (ja)
JP (1) JPS5626660B2 (ja)
KR (1) KR780000072B1 (ja)
AT (1) AT327194B (ja)
AU (1) AU469267B2 (ja)
BE (1) BE803474A (ja)
BG (1) BG22816A3 (ja)
CA (1) CA1016945A (ja)
CH (1) CH583196A5 (ja)
CS (1) CS178892B2 (ja)
DD (1) DD109627A5 (ja)
DE (1) DE2239815C2 (ja)
DK (1) DK136062C (ja)
ES (1) ES417807A1 (ja)
FI (1) FI55998C (ja)
FR (1) FR2195450B1 (ja)
GB (1) GB1384219A (ja)
HU (1) HU167991B (ja)
IE (1) IE37989B1 (ja)
IL (1) IL42933A (ja)
LU (1) LU68206A1 (ja)
NL (1) NL7311031A (ja)
NO (1) NO139130C (ja)
PL (1) PL89396B1 (ja)
RO (1) RO62914A (ja)
SE (1) SE386164B (ja)
SU (1) SU475772A3 (ja)
YU (1) YU36172B (ja)
ZA (1) ZA735460B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2639257A1 (de) * 1976-09-01 1978-03-02 Bayer Ag Aminoalkylidenamino-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4442100A (en) * 1979-12-11 1984-04-10 Bayer Aktiengesellschaft Substituted 2-amino-3,4-dihydropyridine derivatives, their production and their medicinal use
DE3134945A1 (de) * 1981-09-03 1983-03-17 Bayer Ag, 5090 Leverkusen Substituierte 2-amino-3,4-dihydropyridinderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimittel
EP0094159B1 (en) * 1982-05-10 1990-03-14 Takeda Chemical Industries, Ltd. Dihydropyridine derivatives, their production and use
US4603135A (en) * 1983-10-17 1986-07-29 Takeda Chemical Industries, Ltd. Substituted piperazinyl alkyl esters of 2-amino-4-aryl-1,4-dihydro-6-alkyl-3,5-pyridinedicarboxylates
US4678796A (en) * 1984-11-30 1987-07-07 Warner-Lambert Company 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
CA1267416A (en) 1985-06-17 1990-04-03 Ila Sircar 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders
US4732898A (en) * 1986-04-29 1988-03-22 Warner-Lambert Company 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
SE8701172D0 (sv) * 1987-03-20 1987-03-20 Sandvik Ab Whiskerforsterkt keramiskt skerverktyg
EP3730264B1 (en) 2017-12-22 2022-08-24 Toray Industries, Inc. Tape-shaped prepreg and production method therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3441648A (en) * 1967-02-07 1969-04-29 Smithkline Corp Compositions and methods for lowering blood pressure with 1,4-dihydropyridines
DE1670824C3 (de) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-33-dicarbonsäurealkylester
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
DE2013431C3 (de) * 1970-03-20 1979-12-20 Bayer Ag, 5090 Leverkusen 4-Azidophenyl-l,4-dihydropyridin-3,5-dicarbonsäureester

Also Published As

Publication number Publication date
YU36172B (en) 1982-02-25
JPS4945079A (ja) 1974-04-27
JPS5626660B2 (ja) 1981-06-19
SE386164B (sv) 1976-08-02
AU5912473A (en) 1975-02-13
IE37989L (en) 1974-02-12
BG22816A3 (bg) 1977-04-20
ES417807A1 (es) 1976-03-01
CH583196A5 (ja) 1976-12-31
DD109627A5 (ja) 1974-11-12
YU213373A (en) 1981-06-30
AU469267B2 (en) 1976-02-05
PL89396B1 (ja) 1976-11-30
SU475772A3 (ru) 1975-06-30
NO139130B (no) 1978-10-02
IL42933A (en) 1977-04-29
CS178892B2 (en) 1977-10-31
DK136062B (da) 1977-08-08
AT327194B (de) 1976-01-26
DE2239815A1 (de) 1974-02-21
LU68206A1 (ja) 1973-10-16
ZA735460B (en) 1974-07-31
KR780000072B1 (en) 1978-03-30
RO62914A (fr) 1977-11-15
IL42933A0 (en) 1973-11-28
FI55998B (fi) 1979-07-31
FR2195450A1 (ja) 1974-03-08
DE2239815C2 (de) 1983-02-10
HU167991B (ja) 1976-02-28
NO139130C (no) 1979-01-10
DK136062C (da) 1978-01-09
ATA707073A (de) 1975-04-15
GB1384219A (en) 1975-02-19
NL7311031A (ja) 1974-02-14
BE803474A (fr) 1974-02-11
FR2195450B1 (ja) 1977-09-09
US3959292A (en) 1976-05-25
IE37989B1 (en) 1977-11-23
FI55998C (fi) 1979-11-12

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