CA1015745A - 3-substituted-methyl-3-cephem-4-carboxylic acid derivatives and preparation thereof - Google Patents

3-substituted-methyl-3-cephem-4-carboxylic acid derivatives and preparation thereof

Info

Publication number
CA1015745A
CA1015745A CA174,531A CA174531A CA1015745A CA 1015745 A CA1015745 A CA 1015745A CA 174531 A CA174531 A CA 174531A CA 1015745 A CA1015745 A CA 1015745A
Authority
CA
Canada
Prior art keywords
cephem
substituted
methyl
preparation
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA174,531A
Other languages
English (en)
French (fr)
Other versions
CA174531S (en
Inventor
Osamu Nishiwaki
Daizou Morino
Kichizo Endo
Ikuo Ueda
Kiyoshi Hattori
Akira Morimoto
Kazuo Kariyone
Masashi Hashimoto
Masaru Kurita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP6463172A external-priority patent/JPS4924994A/ja
Priority claimed from JP6463072A external-priority patent/JPS5521754B2/ja
Priority claimed from JP6462972A external-priority patent/JPS5525194B2/ja
Priority claimed from JP6557472A external-priority patent/JPS5429517B2/ja
Priority claimed from JP6557572A external-priority patent/JPS5525195B2/ja
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA1015745A publication Critical patent/CA1015745A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CA174,531A 1972-06-27 1973-06-20 3-substituted-methyl-3-cephem-4-carboxylic acid derivatives and preparation thereof Expired CA1015745A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP6463172A JPS4924994A (pt) 1972-06-27 1972-06-27
JP6463072A JPS5521754B2 (pt) 1972-06-27 1972-06-27
JP6462972A JPS5525194B2 (pt) 1972-06-27 1972-06-27
JP6557472A JPS5429517B2 (pt) 1972-06-29 1972-06-29
JP6557572A JPS5525195B2 (pt) 1972-06-29 1972-06-29

Publications (1)

Publication Number Publication Date
CA1015745A true CA1015745A (en) 1977-08-16

Family

ID=27523854

Family Applications (1)

Application Number Title Priority Date Filing Date
CA174,531A Expired CA1015745A (en) 1972-06-27 1973-06-20 3-substituted-methyl-3-cephem-4-carboxylic acid derivatives and preparation thereof

Country Status (6)

Country Link
CA (1) CA1015745A (pt)
CH (1) CH601312A5 (pt)
DE (1) DE2332045A1 (pt)
FR (1) FR2208909B1 (pt)
GB (1) GB1438800A (pt)
SE (1) SE420837B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565941A (en) 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
JPS6027677B2 (ja) 1978-07-06 1985-06-29 富山化学工業株式会社 ７−置換又は非置換アミノ−３−置換チオメチルセフエムカルボン酸類の新規製造法
WO2002086143A2 (en) * 2001-04-19 2002-10-31 Bioferma Murcia, S.A. Enzymatic process for preparing cephalosporin derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH481142A (de) * 1966-12-05 1969-11-15 Ciba Geigy Verfahren zur Isolierung von Cephalosporin C
BE759064A (fr) * 1969-12-17 1971-05-17 Lilly Co Eli Une methode pour transformer la cephalosporine c. en un derive soluble dans un solvant organique, et le compose qui en
GB1311268A (en) * 1971-01-26 1973-03-28 Pfizer Process for the isolation of n-benzoyl cephalosporin c

Also Published As

Publication number Publication date
CH601312A5 (pt) 1978-07-14
GB1438800A (en) 1976-06-09
FR2208909B1 (pt) 1978-01-06
FR2208909A1 (pt) 1974-06-28
SE420837B (sv) 1981-11-02
DE2332045A1 (de) 1974-01-10

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