CA1014548A - Process for preparing primary 3-carbamoyloxymethyl cephalosporins - Google Patents

Process for preparing primary 3-carbamoyloxymethyl cephalosporins

Info

Publication number
CA1014548A
CA1014548A CA161,874A CA161874A CA1014548A CA 1014548 A CA1014548 A CA 1014548A CA 161874 A CA161874 A CA 161874A CA 1014548 A CA1014548 A CA 1014548A
Authority
CA
Canada
Prior art keywords
preparing primary
carbamoyloxymethyl
cephalosporins
carbamoyloxymethyl cephalosporins
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA161,874A
Other languages
English (en)
Other versions
CA161874S (en
Inventor
John A. Webber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of CA1014548A publication Critical patent/CA1014548A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CA161,874A 1972-01-25 1973-01-23 Process for preparing primary 3-carbamoyloxymethyl cephalosporins Expired CA1014548A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US220697A US3905963A (en) 1972-01-25 1972-01-25 Process for preparing primary 3-carbamoyloxymethyl cephalosporins

Publications (1)

Publication Number Publication Date
CA1014548A true CA1014548A (en) 1977-07-26

Family

ID=22824586

Family Applications (1)

Application Number Title Priority Date Filing Date
CA161,874A Expired CA1014548A (en) 1972-01-25 1973-01-23 Process for preparing primary 3-carbamoyloxymethyl cephalosporins

Country Status (24)

Country Link
US (1) US3905963A (fi)
JP (1) JPS5538956B2 (fi)
AR (1) AR196324A1 (fi)
AT (1) AT325764B (fi)
AU (1) AU465060B2 (fi)
BE (1) BE794389A (fi)
BG (1) BG22403A3 (fi)
CA (1) CA1014548A (fi)
CH (1) CH567513A5 (fi)
CS (1) CS192502B2 (fi)
DD (1) DD103246A5 (fi)
DE (1) DE2303022C2 (fi)
ES (1) ES410946A1 (fi)
FR (1) FR2181687B1 (fi)
GB (1) GB1409633A (fi)
HU (1) HU170132B (fi)
IE (1) IE37138B1 (fi)
IL (1) IL41310A (fi)
NL (1) NL7301038A (fi)
PL (1) PL83446B1 (fi)
RO (1) RO62820A (fi)
SE (1) SE418293B (fi)
YU (1) YU36973B (fi)
ZA (1) ZA73320B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4173703A (en) * 1971-12-14 1979-11-06 Merck & Co., Inc. Preparation of carbamates
GB1449420A (en) * 1973-11-26 1976-09-15 Sankyo Co 7alpha-methoxycephalosporing derivatives
US4198503A (en) * 1974-11-05 1980-04-15 Beecham Group Limited 3-Carbamoyl substituted-7-ureido substituted cephalosporins
US4121041A (en) * 1977-02-04 1978-10-17 Merck & Co., Inc. 7-(Amidinothio)acetamido-7-methoxy cephalosporins
CA1128930A (en) * 1978-04-07 1982-08-03 Stuart B. Laing Cephalosporin compounds
ZA80844B (en) * 1979-02-15 1981-08-26 Glaxo Group Ltd Preparation of sodium cefuroxime
CA1178489A (en) * 1981-11-10 1984-11-27 Roy A. Young Weather stripping
CN110204557B (zh) * 2019-07-02 2021-08-20 苏州盛达药业有限公司 一种头孢孟多酯钠衍生物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1445633A1 (de) * 1963-10-07 1968-12-05 Ciba Geigy Verfahren zur Herstellung neuer Amide
BE664955A (fi) * 1964-06-05
US3632578A (en) * 1968-09-09 1972-01-04 Lilly Co Eli Cleavage of acylamidocephalosporins and acylamidopenicillins
US3706746A (en) * 1968-11-07 1972-12-19 Ciba Geigy Corp O-desacetyl derivatives of 7-n-acylamino-cephalosphoranic acids
US3632810A (en) * 1968-12-11 1972-01-04 Ciba Geigy Corp Derivatives of 7-amino cephalosporanic acid
GB1350772A (en) * 1971-01-27 1974-04-24 Merck & Co Inc Antibiotics and processes for their production
CH593924A5 (en) * 1971-08-25 1977-12-30 Merck & Co Inc Cephalosporin carbamates - from alcohols and isocyanates

Also Published As

Publication number Publication date
JPS5538956B2 (fi) 1980-10-07
CH567513A5 (fi) 1975-10-15
ZA73320B (en) 1974-08-28
AU465060B2 (en) 1975-09-18
IE37138L (en) 1973-07-25
DE2303022A1 (de) 1973-08-09
NL7301038A (fi) 1973-07-27
RO62820A (fr) 1977-11-15
GB1409633A (en) 1975-10-08
FR2181687B1 (fi) 1976-07-02
BE794389A (fr) 1973-07-23
AR196324A1 (es) 1973-12-18
IL41310A0 (en) 1973-03-30
IL41310A (en) 1976-06-30
AU5122673A (en) 1974-07-18
YU36973B (en) 1984-08-31
ES410946A1 (es) 1976-05-16
AT325764B (de) 1975-11-10
FR2181687A1 (fi) 1973-12-07
ATA57773A (de) 1975-01-15
CS192502B2 (en) 1979-08-31
PL83446B1 (fi) 1975-12-31
BG22403A3 (bg) 1977-02-20
IE37138B1 (en) 1977-05-11
US3905963A (en) 1975-09-16
DE2303022C2 (de) 1984-01-12
DD103246A5 (fi) 1974-01-12
YU20173A (en) 1982-06-18
SE418293B (sv) 1981-05-18
JPS4881887A (fi) 1973-11-01
HU170132B (fi) 1977-04-28

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