CA1005342A - Pharmaceutical composition containing nicotinic acid derivatives - Google Patents

Pharmaceutical composition containing nicotinic acid derivatives

Info

Publication number
CA1005342A
CA1005342A CA127,942A CA127942A CA1005342A CA 1005342 A CA1005342 A CA 1005342A CA 127942 A CA127942 A CA 127942A CA 1005342 A CA1005342 A CA 1005342A
Authority
CA
Canada
Prior art keywords
pharmaceutical composition
composition containing
acid derivatives
nicotinic acid
containing nicotinic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA127,942A
Other languages
English (en)
Other versions
CA127942S (en
Inventor
Oscar N. Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1005342A publication Critical patent/CA1005342A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
CA127,942A 1970-11-23 1971-11-18 Pharmaceutical composition containing nicotinic acid derivatives Expired CA1005342A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9213770A 1970-11-23 1970-11-23

Publications (1)

Publication Number Publication Date
CA1005342A true CA1005342A (en) 1977-02-15

Family

ID=22231809

Family Applications (1)

Application Number Title Priority Date Filing Date
CA127,942A Expired CA1005342A (en) 1970-11-23 1971-11-18 Pharmaceutical composition containing nicotinic acid derivatives

Country Status (12)

Country Link
US (1) US3709991A (fr)
AT (1) AT319240B (fr)
AU (1) AU456174B2 (fr)
BE (1) BE775640A (fr)
CA (1) CA1005342A (fr)
DE (1) DE2157333A1 (fr)
FR (1) FR2115358B1 (fr)
GB (1) GB1344118A (fr)
IE (1) IE35824B1 (fr)
IL (1) IL38090A (fr)
NL (1) NL7116091A (fr)
ZA (2) ZA717344B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2803592A1 (de) * 1978-01-27 1979-08-02 Scott Eugene J Van Therapeutisches mittel
US4891220A (en) * 1988-07-14 1990-01-02 Immudyne, Inc. Method and composition for treating hyperlipidemia
US6080428A (en) * 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US20080045573A1 (en) * 1993-09-20 2008-02-21 Bova David J Methods and Sustained Release Nicotinic Acid Compositions for Treating Hyperlipidemia
US6129930A (en) * 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6676967B1 (en) * 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US20060263428A1 (en) * 1993-09-20 2006-11-23 Eugenio Cefali Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics

Also Published As

Publication number Publication date
AU456174B2 (en) 1974-12-12
AT319240B (de) 1974-12-10
ZA717344B (en) 1972-12-27
FR2115358B1 (fr) 1975-10-10
IL38090A0 (en) 1972-01-27
US3709991A (en) 1973-01-09
IE35824L (en) 1972-05-23
IE35824B1 (en) 1976-05-26
DE2157333A1 (de) 1972-05-31
ZA717345B (en) 1972-11-29
BE775640A (fr) 1972-05-23
IL38090A (en) 1974-07-31
FR2115358A1 (fr) 1972-07-07
AU3556371A (en) 1973-05-17
GB1344118A (en) 1974-01-16
NL7116091A (fr) 1972-05-25

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