CA1003838A - 1,4-bis-acylpiperazines - Google Patents

1,4-bis-acylpiperazines

Info

Publication number
CA1003838A
CA1003838A CA147,596A CA147596A CA1003838A CA 1003838 A CA1003838 A CA 1003838A CA 147596 A CA147596 A CA 147596A CA 1003838 A CA1003838 A CA 1003838A
Authority
CA
Canada
Prior art keywords
acylpiperazines
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA147,596A
Other languages
English (en)
Other versions
CA147596S (en
Inventor
Tellis A. Martin
William T. Comer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Canada Inc
Original Assignee
Bristol Myers Canada Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Canada Ltd filed Critical Bristol Myers Canada Ltd
Application granted granted Critical
Publication of CA1003838A publication Critical patent/CA1003838A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA147,596A 1971-10-07 1972-07-20 1,4-bis-acylpiperazines Expired CA1003838A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00187257A US3809697A (en) 1971-10-07 1971-10-07 1,4-bis-acylpiperazines

Publications (1)

Publication Number Publication Date
CA1003838A true CA1003838A (en) 1977-01-18

Family

ID=22688238

Family Applications (1)

Application Number Title Priority Date Filing Date
CA147,596A Expired CA1003838A (en) 1971-10-07 1972-07-20 1,4-bis-acylpiperazines

Country Status (11)

Country Link
US (1) US3809697A (fr)
JP (1) JPS4844273A (fr)
AU (1) AU463873B2 (fr)
BE (1) BE789811A (fr)
CA (1) CA1003838A (fr)
DE (1) DE2249054A1 (fr)
FR (1) FR2161910B1 (fr)
GB (1) GB1370980A (fr)
NL (1) NL7213558A (fr)
SE (1) SE386175B (fr)
ZA (1) ZA727046B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005222A (en) * 1975-05-21 1977-01-25 Mead Johnson & Company Mucolytic mercaptoacylamidobenzoic and benzenesulfonic acid compounds and process
US4132802A (en) * 1976-10-18 1979-01-02 Mead Johnson & Company Benzoic acid derivative and benzenesulfonic acid mucolytic process
US4093739A (en) * 1977-06-15 1978-06-06 Mead Johnson & Company Mercaptoacylamidobenzoyl glycine and mucolytic process
US4198509A (en) * 1978-10-30 1980-04-15 E. R. Squibb & Sons, Inc. Mercaptoacylpiperazine carboxylic acid compounds
FR2854568B1 (fr) * 2003-05-06 2007-11-02 Oreal Utilisation de dithiols dans une composition de deformation permanente des cheveux
MX2017009764A (es) * 2015-01-30 2018-03-28 Parion Sciences Inc Agentes mucolíticos de monotiol novedosos.
CA2984424A1 (fr) 2015-04-30 2016-11-03 Parion Sciences, Inc. Nouveaux promedicaments d'agents mucolytiques a base de dithiol

Also Published As

Publication number Publication date
AU463873B2 (en) 1975-08-07
FR2161910B1 (fr) 1976-03-05
FR2161910A1 (fr) 1973-07-13
US3809697A (en) 1974-05-07
NL7213558A (fr) 1973-04-10
ZA727046B (en) 1973-06-27
DE2249054A1 (de) 1973-04-26
SE386175B (sv) 1976-08-02
JPS4844273A (fr) 1973-06-26
GB1370980A (en) 1974-10-23
AU4744372A (en) 1974-04-11
BE789811A (fr) 1973-04-06

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