BRPI0919020B8 - use of enriched monocyte lineage cells to treat ischemia and to treat angina pectoris - Google Patents

use of enriched monocyte lineage cells to treat ischemia and to treat angina pectoris

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Publication number
BRPI0919020B8
BRPI0919020B8 BRPI0919020A BRPI0919020A BRPI0919020B8 BR PI0919020 B8 BRPI0919020 B8 BR PI0919020B8 BR PI0919020 A BRPI0919020 A BR PI0919020A BR PI0919020 A BRPI0919020 A BR PI0919020A BR PI0919020 B8 BRPI0919020 B8 BR PI0919020B8
Authority
BR
Brazil
Prior art keywords
treat
ischemia
angina pectoris
lineage cells
monocyte lineage
Prior art date
Application number
BRPI0919020A
Other languages
Portuguese (pt)
Inventor
Invitti Adriana
E Willing Alison
Hossne Nelson
R Sanberg Paul
Original Assignee
Cryopraxis Criobiologia Ltda
Univ Federal De Sao Paulo Unifesp
Univ South Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cryopraxis Criobiologia Ltda, Univ Federal De Sao Paulo Unifesp, Univ South Florida filed Critical Cryopraxis Criobiologia Ltda
Publication of BRPI0919020A8 publication Critical patent/BRPI0919020A8/en
Publication of BRPI0919020B1 publication Critical patent/BRPI0919020B1/en
Publication of BRPI0919020B8 publication Critical patent/BRPI0919020B8/en

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Abstract

uso de células de linhagem monocitária enriquecidas para tratar isquemia e para tratar angina pectoris. a presente invenção refere-se a composições e métodos para o tratamento de doenças e condições isquêmicas, particularmente isquemia do miocárdio, do snc/cérebro e de membros. mais particularmente, a presente invenção estabelece métodos de tratamento de doenças mediante administração de monócitos obtidos de sangue, incluindo sangue de cordão umbilical, sangue periférico ou medula óssea, a um indivíduo que precisa de tratamento, em que a formulação específica é administrada para o indivíduo, em um tempo especificamente determinado para proporcionar a eficácia terapêutica. em uma modalidade, as células são para injeção no miocárdio isquêmico para o tratamento de angina.use of enriched monocyte lineage cells to treat ischemia and to treat angina pectoris. The present invention relates to compositions and methods for treating ischemic diseases and conditions, particularly myocardial, snc/brain and limb ischemia. more particularly, the present invention provides methods of treating diseases by administering monocytes obtained from blood, including umbilical cord blood, peripheral blood or bone marrow, to an individual in need of treatment, wherein the specific formulation is administered to the individual. , at a time specifically determined to provide therapeutic efficacy. in one embodiment, the cells are for injection into the ischemic myocardium for the treatment of angina.

BRPI0919020A 2008-09-12 2009-09-14 use of enriched monocyte lineage cells to treat ischemia and to treat angina pectoris BRPI0919020B8 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9672708P 2008-09-12 2008-09-12
US61/096,727 2008-09-12
US17380709P 2009-04-29 2009-04-29
US61/173,807 2009-04-29
PCT/US2009/056867 WO2010031006A1 (en) 2008-09-12 2009-09-14 Ischemic tissue cell therapy

Publications (3)

Publication Number Publication Date
BRPI0919020A8 BRPI0919020A8 (en) 2018-05-29
BRPI0919020B1 BRPI0919020B1 (en) 2021-03-23
BRPI0919020B8 true BRPI0919020B8 (en) 2021-05-25

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ID=42005531

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0919020D BRPI0919020A2 (en) 2008-09-12 2009-09-14 USE OF ENRICHED MONOCYTE LINE CELLS TO TREAT ISCHEMIA AND TO TREAT ANGINA PECTORIS
BRPI0919020A BRPI0919020B8 (en) 2008-09-12 2009-09-14 use of enriched monocyte lineage cells to treat ischemia and to treat angina pectoris

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI0919020D BRPI0919020A2 (en) 2008-09-12 2009-09-14 USE OF ENRICHED MONOCYTE LINE CELLS TO TREAT ISCHEMIA AND TO TREAT ANGINA PECTORIS

Country Status (9)

Country Link
US (2) US8784802B2 (en)
EP (1) EP2331679B1 (en)
JP (4) JP6105846B2 (en)
CN (2) CN102186970A (en)
BR (2) BRPI0919020A2 (en)
CA (1) CA2737193A1 (en)
HK (1) HK1248125A1 (en)
RU (1) RU2535966C2 (en)
WO (1) WO2010031006A1 (en)

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US20110274674A1 (en) 2011-11-10
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RU2535966C2 (en) 2014-12-20
WO2010031006A1 (en) 2010-03-18
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CN107595889A (en) 2018-01-19
US8784802B2 (en) 2014-07-22
CA2737193A1 (en) 2010-03-18
JP2016128521A (en) 2016-07-14
US20140369983A1 (en) 2014-12-18
JP2017214426A (en) 2017-12-07
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EP2331679A4 (en) 2012-12-26
JP6105846B2 (en) 2017-03-29
EP2331679B1 (en) 2017-04-19
JP2012502114A (en) 2012-01-26
BRPI0919020A8 (en) 2018-05-29
US10335434B2 (en) 2019-07-02
RU2011113869A (en) 2012-10-20
BRPI0919020A2 (en) 2017-08-22

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