BRPI0918739A2 - anticorpo, composição, molécula de ácido nucleico, método de tratamento de tumor maligno em animais, e, uso da composição. - Google Patents
anticorpo, composição, molécula de ácido nucleico, método de tratamento de tumor maligno em animais, e, uso da composição.Info
- Publication number
- BRPI0918739A2 BRPI0918739A2 BRPI0918739A BRPI0918739A BRPI0918739A2 BR PI0918739 A2 BRPI0918739 A2 BR PI0918739A2 BR PI0918739 A BRPI0918739 A BR PI0918739A BR PI0918739 A BRPI0918739 A BR PI0918739A BR PI0918739 A2 BRPI0918739 A2 BR PI0918739A2
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- antibody
- animals
- nucleic acid
- acid molecule
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9869708P | 2008-09-19 | 2008-09-19 | |
US11955808P | 2008-12-03 | 2008-12-03 | |
PCT/GB2009/051218 WO2010032061A1 (en) | 2008-09-19 | 2009-09-18 | Antibodies against sonic hedgehog homolog and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0918739A2 true BRPI0918739A2 (pt) | 2017-09-26 |
Family
ID=41237627
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0918739A BRPI0918739A2 (pt) | 2008-09-19 | 2009-09-18 | anticorpo, composição, molécula de ácido nucleico, método de tratamento de tumor maligno em animais, e, uso da composição. |
Country Status (10)
Country | Link |
---|---|
US (2) | US8207306B2 (pt) |
EP (1) | EP2344535A1 (pt) |
JP (1) | JP2012502967A (pt) |
KR (1) | KR20110059755A (pt) |
CN (1) | CN102203135A (pt) |
AU (1) | AU2009294416B2 (pt) |
BR (1) | BRPI0918739A2 (pt) |
CA (1) | CA2734330A1 (pt) |
MX (1) | MX2011002838A (pt) |
WO (1) | WO2010032061A1 (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8207306B2 (en) * | 2008-09-19 | 2012-06-26 | Medimmune, Llc | Targeted binding agents directed to sonic hedgehog homolog and uses thereof |
AU2011223789A1 (en) | 2010-03-01 | 2012-09-20 | Caris Life Sciences Switzerland Holdings Gmbh | Biomarkers for theranostics |
CA2795776A1 (en) | 2010-04-06 | 2011-10-13 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers for disease |
NZ605260A (en) * | 2010-06-14 | 2013-12-20 | Joseph King Allan | Anti-vegf antibodies and uses thereof |
EP2806948B1 (en) * | 2012-01-27 | 2020-01-15 | New York University | Method for enhancing remyelination using gli1 inhibitors |
US20150272970A1 (en) * | 2012-09-07 | 2015-10-01 | Carlos Cordon-Cardo | Targeting chemotherapy agent resistance in cancer |
JP2016530243A (ja) * | 2013-07-18 | 2016-09-29 | アン アンド ロバート エイチ.ルリー チルドレンズ ホスピタル オブ シカゴ | 神経管欠損症を検出及び治療する組成物及び方法 |
NL2011406C2 (en) | 2013-09-06 | 2015-03-10 | Bionovion Holding B V | Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides. |
WO2015057906A1 (en) * | 2013-10-16 | 2015-04-23 | Janssen Biotech, Inc. | Cd200 receptor 1 agonists |
EP3088517B1 (en) | 2013-12-26 | 2023-11-01 | Mitsubishi Tanabe Pharma Corporation | Human anti-il-33 neutralizing monoclonal antibody |
NL2014108B1 (en) * | 2015-01-09 | 2016-09-30 | Aduro Biotech Holdings Europe B V | Altered april binding antibodies. |
CN109071665B (zh) * | 2016-04-18 | 2022-11-01 | 塞德斯医疗公司 | 结合人cd40的激动性抗体及其用途 |
US11479601B2 (en) * | 2016-06-29 | 2022-10-25 | The Regents Of The University Of California | Antibodies specific to Sonic Hedgehog and method of use thereof |
CN110506057B (zh) | 2017-02-17 | 2023-09-29 | 百时美施贵宝公司 | Alpha突触核蛋白抗体及其应用 |
WO2019045075A1 (ja) | 2017-08-31 | 2019-03-07 | 田辺三菱製薬株式会社 | Il-33アンタゴニストを含む子宮内膜症治療剤 |
JOP20200157A1 (ar) | 2017-12-22 | 2022-10-30 | Teneobio Inc | أجسام مضادة ذات سلسلة ثقيلة ترتبط بـ cd22 |
WO2019164891A1 (en) * | 2018-02-21 | 2019-08-29 | Celgene Corporation | Bcma-binding antibodies and uses thereof |
UY38748A (es) | 2019-06-14 | 2021-01-29 | Teneobio Inc | Anticuerpos multiespecíficos de cadena pesada que se unen a cd22 y cd3 |
CN113025614B (zh) * | 2021-03-22 | 2022-08-19 | 四川大学华西医院 | 一种胶质瘤诊断和/或预后评估标志物及其应用 |
WO2023152567A2 (en) * | 2022-02-14 | 2023-08-17 | The Hong Kong University Of Science And Technology | Disruption of sonic hedgehog-surf4 interaction for cancer treatment |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8207306B2 (en) * | 2008-09-19 | 2012-06-26 | Medimmune, Llc | Targeted binding agents directed to sonic hedgehog homolog and uses thereof |
-
2009
- 2009-09-18 US US12/562,435 patent/US8207306B2/en not_active Expired - Fee Related
- 2009-09-18 BR BRPI0918739A patent/BRPI0918739A2/pt not_active IP Right Cessation
- 2009-09-18 KR KR1020117007825A patent/KR20110059755A/ko not_active Application Discontinuation
- 2009-09-18 JP JP2011527408A patent/JP2012502967A/ja active Pending
- 2009-09-18 CN CN2009801424304A patent/CN102203135A/zh active Pending
- 2009-09-18 CA CA2734330A patent/CA2734330A1/en not_active Abandoned
- 2009-09-18 EP EP09785668A patent/EP2344535A1/en not_active Withdrawn
- 2009-09-18 WO PCT/GB2009/051218 patent/WO2010032061A1/en active Application Filing
- 2009-09-18 AU AU2009294416A patent/AU2009294416B2/en not_active Ceased
- 2009-09-18 MX MX2011002838A patent/MX2011002838A/es not_active Application Discontinuation
-
2012
- 2012-05-23 US US13/478,580 patent/US8569459B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2010032061A1 (en) | 2010-03-25 |
JP2012502967A (ja) | 2012-02-02 |
KR20110059755A (ko) | 2011-06-03 |
US8569459B2 (en) | 2013-10-29 |
AU2009294416A1 (en) | 2010-03-25 |
CN102203135A (zh) | 2011-09-28 |
MX2011002838A (es) | 2011-07-29 |
AU2009294416B2 (en) | 2014-05-22 |
CA2734330A1 (en) | 2010-03-25 |
US20120328625A1 (en) | 2012-12-27 |
US8207306B2 (en) | 2012-06-26 |
EP2344535A1 (en) | 2011-07-20 |
US20100196388A1 (en) | 2010-08-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B15I | Others concerning applications: loss of priority | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |