BRPI0813535A2 - MICROFLUID REACTOR ARRANGEMENT, METHODS FOR PRODUCING A MICROFLUID REACTOR ARRANGEMENT, TO OPERATE AT LEAST ONE MICROFLUID REACTOR ARRANGEMENT AND TO DETECT AN ANALYST IN A FLUID SAMPLE, AND USE OF A MICROFLUID REACTOR. - Google Patents
MICROFLUID REACTOR ARRANGEMENT, METHODS FOR PRODUCING A MICROFLUID REACTOR ARRANGEMENT, TO OPERATE AT LEAST ONE MICROFLUID REACTOR ARRANGEMENT AND TO DETECT AN ANALYST IN A FLUID SAMPLE, AND USE OF A MICROFLUID REACTOR.Info
- Publication number
- BRPI0813535A2 BRPI0813535A2 BRPI0813535-5A2A BRPI0813535A BRPI0813535A2 BR PI0813535 A2 BRPI0813535 A2 BR PI0813535A2 BR PI0813535 A BRPI0813535 A BR PI0813535A BR PI0813535 A2 BRPI0813535 A2 BR PI0813535A2
- Authority
- BR
- Brazil
- Prior art keywords
- reactor arrangement
- reagent
- microfluid
- microfluid reactor
- arrangement
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
A micro fluidic reactor arrangement (100) for use in detecting an analyte in a fluid sample (106) is described. The reactor arrangement is provided with a reagent providing means such that the reagent can be introduced after assembly of the reactor arrangement. The latter can be performed by introducing the reagent in the form of a solution or a dispersion and fixing it on a holding means (118) by removal of the liquid, i.e. by drying, the holding means comprising the reagent in a solid version in the detector chamber. Prior to the introduction of the reagent, components of the reactor arrangement already present, such as the sample inlet can be hydrophilised by a wetting hydrophilising technique. The invention relates to a manufacturing technique as well as to the resulting product. The invention furthermore relates to functionalizing of the reactor arrangement with a particular reagent for particular applications. The latter can be performed well after fabrication and assembly of the major reactor arrangement components.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07112834A EP2017006A1 (en) | 2007-07-20 | 2007-07-20 | Microfluidic methods and systems for use in detecting analytes |
PCT/IB2008/052803 WO2009013658A2 (en) | 2007-07-20 | 2008-07-11 | Microfluidic methods and systems for use in detecting analytes |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0813535A2 true BRPI0813535A2 (en) | 2014-12-30 |
Family
ID=38695477
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0813535-5A2A BRPI0813535A2 (en) | 2007-07-20 | 2008-07-11 | MICROFLUID REACTOR ARRANGEMENT, METHODS FOR PRODUCING A MICROFLUID REACTOR ARRANGEMENT, TO OPERATE AT LEAST ONE MICROFLUID REACTOR ARRANGEMENT AND TO DETECT AN ANALYST IN A FLUID SAMPLE, AND USE OF A MICROFLUID REACTOR. |
Country Status (8)
Country | Link |
---|---|
US (1) | US20100233824A1 (en) |
EP (2) | EP2017006A1 (en) |
JP (1) | JP2010534319A (en) |
CN (1) | CN101754813A (en) |
AT (1) | ATE547176T1 (en) |
BR (1) | BRPI0813535A2 (en) |
RU (1) | RU2010106175A (en) |
WO (1) | WO2009013658A2 (en) |
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EP2017618A1 (en) * | 2007-07-20 | 2009-01-21 | Koninklijke Philips Electronics N.V. | Methods and systems for detecting |
US9086396B2 (en) * | 2008-11-28 | 2015-07-21 | Roche Molecular Systems, Inc. | System and method for the automated processing of fluids, method for determining the matching of objects |
US9121887B2 (en) | 2009-02-26 | 2015-09-01 | Regents Of The University Of Minnesota | High magnetic moment particle detection |
DE102009040151B4 (en) * | 2009-05-26 | 2013-09-12 | Analytik Jena Ag | Arrangement for the detection of chemiluminescence on gases |
DE102009048378B3 (en) * | 2009-10-06 | 2011-02-17 | INSTITUT FüR MIKROTECHNIK MAINZ GMBH | Microfluidic structure |
JP5506440B2 (en) * | 2010-02-08 | 2014-05-28 | 株式会社堀場製作所 | Liquid sample quantifier |
US9372133B2 (en) | 2010-06-30 | 2016-06-21 | Metaboscreen Co., Ltd. | Microchemical chip, producing method thereof and method for using the microchemical chip |
KR101363157B1 (en) * | 2010-10-07 | 2014-02-26 | 주식회사 세라젬메디시스 | three-dimensional biosensor |
DE102012205171B3 (en) * | 2012-03-29 | 2013-09-12 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Integrated disposable chip cartridge system for mobile multi-parameter analysis of chemical and / or biological substances |
DE102012109026A1 (en) * | 2012-09-25 | 2014-03-27 | Eads Deutschland Gmbh | Detection device and detection method for the automatic determination of biomass |
CN102836751B (en) * | 2012-09-28 | 2014-11-19 | 重庆大学 | Hydrogel micro-fluidic chip and processing method thereof |
US20140322706A1 (en) | 2012-10-24 | 2014-10-30 | Jon Faiz Kayyem | Integrated multipelx target analysis |
EP2912432B1 (en) | 2012-10-24 | 2018-07-04 | Genmark Diagnostics Inc. | Integrated multiplex target analysis |
CN103846640B (en) * | 2012-12-07 | 2017-02-15 | 哈尔滨工业大学深圳研究生院 | Plasma electro-discharge machining device and machining method of micro holes |
CN105228748B (en) | 2013-03-15 | 2017-10-10 | 金马克诊断股份有限公司 | System, method and apparatus for manipulating deformable fluid container |
US10155244B2 (en) * | 2013-09-16 | 2018-12-18 | Taiwan Semiconductor Manufacturing Co., Ltd. | Fluid deposition appartus and method |
DE102013220908B4 (en) * | 2013-10-15 | 2015-09-24 | Continental Automotive Gmbh | sensor element |
USD881409S1 (en) | 2013-10-24 | 2020-04-14 | Genmark Diagnostics, Inc. | Biochip cartridge |
US9498778B2 (en) | 2014-11-11 | 2016-11-22 | Genmark Diagnostics, Inc. | Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system |
US9797899B2 (en) * | 2013-11-06 | 2017-10-24 | Becton, Dickinson And Company | Microfluidic devices, and methods of making and using the same |
EP2957912A1 (en) * | 2014-06-17 | 2015-12-23 | University College Dublin | A method of labelling a target molecule forming part of a corona of molecules on a surface of a nanosized object |
CN104166008B (en) * | 2014-08-11 | 2016-03-02 | 江苏大学 | A kind of micro-fluidic chip automatic synchronization sample injection method and device |
US10005080B2 (en) | 2014-11-11 | 2018-06-26 | Genmark Diagnostics, Inc. | Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation |
CN107466367A (en) * | 2014-12-03 | 2017-12-12 | Uwm研究基金会有限公司 | Pollutant testing apparatus and method |
CN104597242B (en) * | 2015-02-06 | 2016-07-06 | 无锡市人民医院 | A kind of biochip realizing tumor markers enrichment and application thereof |
US10369567B2 (en) * | 2015-11-04 | 2019-08-06 | International Business Machines Corporation | Continuous, capacitance-based monitoring of liquid flows in a microfluidic device |
GB201611770D0 (en) * | 2016-07-06 | 2016-08-17 | Oxford Nanopore Tech | Microfluidic device |
US11278897B2 (en) | 2017-12-28 | 2022-03-22 | Stmicroelectronics S.R.L. | Cartridge for sample preparation and molecule analysis, cartridge control machine, sample preparation system and method using the cartridge |
US11511278B2 (en) | 2017-12-28 | 2022-11-29 | Stmicroelectronics S.R.L. | Solid reagent containment unit, in particular for a portable microfluidic device for sample preparation and molecule analysis |
US11491489B2 (en) | 2017-12-28 | 2022-11-08 | Stmicroelectronics S.R.L. | Microfluidic connector group, microfluidic device and manufacturing process thereof, in particular for a cartridge for sample preparation and molecule analysis |
US11717825B2 (en) | 2017-12-28 | 2023-08-08 | Stmicroelectronics S.R.L. | Magnetically controllable valve and portable microfluidic device having a magnetically controllable valve, in particular cartridge for sample preparation and molecule analysis |
US11110457B2 (en) * | 2017-12-28 | 2021-09-07 | Stmicroelectronics S.R.L. | Analysis unit for a transportable microfluidic device, in particular for sample preparation and molecule analysis |
US20210231673A1 (en) * | 2018-08-17 | 2021-07-29 | President And Fellows Of Harvard College | Methods and compositions for detection and quantification of small molecules and other analytes |
CN112169853B (en) * | 2020-12-01 | 2021-02-26 | 南京岚煜生物科技有限公司 | Multifunctional microfluidic detection chip |
CN113426497B (en) * | 2021-06-02 | 2022-07-12 | 广州大学 | Method for manufacturing micro-fluidic chip |
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DE2424291C3 (en) * | 1974-05-18 | 1978-09-21 | Hoechst Ag, 6000 Frankfurt | Process for the production of hydrophilic polyolefin fibers containing inorganic pigment |
ATE272213T1 (en) * | 1999-06-18 | 2004-08-15 | Gamera Bioscience Corp | DEVICES AND METHODS FOR PERFORMING MINIATURIZED HOMOGENEOUS TESTS |
JP3442338B2 (en) * | 2000-03-17 | 2003-09-02 | 株式会社日立製作所 | DNA analyzer, DNA base sequencer, DNA base sequence determination method, and reaction module |
DE10111457B4 (en) * | 2001-03-09 | 2006-12-14 | Siemens Ag | diagnostic device |
AU2002326314A1 (en) * | 2001-06-20 | 2003-01-08 | Teragenics, Inc. | Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system |
EP1615031A4 (en) * | 2003-04-16 | 2011-01-12 | Arkray Inc | Analyzing tool being reduced in distance of diffusion of reagent and method for manufacture thereof |
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CA2615278A1 (en) * | 2005-08-31 | 2007-03-08 | Egomedical Technologies Ag | Coagulation test system |
-
2007
- 2007-07-20 EP EP07112834A patent/EP2017006A1/en not_active Ceased
-
2008
- 2008-07-11 CN CN200880025402.XA patent/CN101754813A/en active Pending
- 2008-07-11 WO PCT/IB2008/052803 patent/WO2009013658A2/en active Application Filing
- 2008-07-11 AT AT08789279T patent/ATE547176T1/en active
- 2008-07-11 EP EP08789279A patent/EP2170515B1/en not_active Not-in-force
- 2008-07-11 US US12/669,213 patent/US20100233824A1/en not_active Abandoned
- 2008-07-11 BR BRPI0813535-5A2A patent/BRPI0813535A2/en not_active IP Right Cessation
- 2008-07-11 RU RU2010106175/05A patent/RU2010106175A/en not_active Application Discontinuation
- 2008-07-11 JP JP2010516624A patent/JP2010534319A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2009013658A3 (en) | 2009-03-12 |
EP2170515B1 (en) | 2012-02-29 |
EP2170515A2 (en) | 2010-04-07 |
EP2017006A1 (en) | 2009-01-21 |
CN101754813A (en) | 2010-06-23 |
ATE547176T1 (en) | 2012-03-15 |
US20100233824A1 (en) | 2010-09-16 |
RU2010106175A (en) | 2011-08-27 |
JP2010534319A (en) | 2010-11-04 |
WO2009013658A2 (en) | 2009-01-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |