BRPI0721725A2 - Preparação de derivados semi-sintéticos e bioativos, a partir de 4-nerolidilcatecol e dilapiol. - Google Patents

Preparação de derivados semi-sintéticos e bioativos, a partir de 4-nerolidilcatecol e dilapiol.

Info

Publication number
BRPI0721725A2
BRPI0721725A2 BRPI0721725-0A BRPI0721725A BRPI0721725A2 BR PI0721725 A2 BRPI0721725 A2 BR PI0721725A2 BR PI0721725 A BRPI0721725 A BR PI0721725A BR PI0721725 A2 BRPI0721725 A2 BR PI0721725A2
Authority
BR
Brazil
Prior art keywords
nerolidylcatechol
dilapiol
semi
synthetic
preparation
Prior art date
Application number
BRPI0721725-0A
Other languages
English (en)
Inventor
Ana Cristina Da Silva Pinto
Márcia Rúbia Silva Melo
Valter Ferreira De Andrade Neto
Francisco Célio Maia Chaves
Pedro Paulo Ribeiro Vieira
Adrian Martin Pohlit
Original Assignee
Inst Nac De Pesquisas Da Amazônia Inpa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nac De Pesquisas Da Amazônia Inpa filed Critical Inst Nac De Pesquisas Da Amazônia Inpa
Publication of BRPI0721725A2 publication Critical patent/BRPI0721725A2/pt
Publication of BRPI0721725B1 publication Critical patent/BRPI0721725B1/pt
Publication of BRPI0721725B8 publication Critical patent/BRPI0721725B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/18—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring
    • C07C39/19—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring containing carbon-to-carbon double bonds but no carbon-to-carbon triple bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/004—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by obtaining phenols from plant material or from animal material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/017—Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78—Benzoic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
BRPI0721725A 2007-12-28 2007-12-28 derivados de 4-nerolidilcatecol, composições farmacêuticas compreendendo os mesmos, e processo para a produçâo de derivados de 4-nerolidilcatecol BRPI0721725B8 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/BR2007/000373 WO2009082795A1 (en) 2007-12-28 2007-12-28 Derivatives of 4-nerolidylcatechol, pharmaceutical compositions comprising them and process for producing the same

Publications (3)

Publication Number Publication Date
BRPI0721725A2 true BRPI0721725A2 (pt) 2015-08-04
BRPI0721725B1 BRPI0721725B1 (pt) 2020-02-11
BRPI0721725B8 BRPI0721725B8 (pt) 2021-05-25

Family

ID=40823713

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0721725A BRPI0721725B8 (pt) 2007-12-28 2007-12-28 derivados de 4-nerolidilcatecol, composições farmacêuticas compreendendo os mesmos, e processo para a produçâo de derivados de 4-nerolidilcatecol

Country Status (4)

Country Link
US (1) US8673971B2 (pt)
EP (1) EP2222624A4 (pt)
BR (1) BRPI0721725B8 (pt)
WO (1) WO2009082795A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103145646B (zh) * 2013-03-21 2015-03-11 苏州太湖电工新材料股份有限公司 一种含硫环氧树脂及其制备方法
CN103254724B (zh) * 2013-05-17 2015-05-06 苏州太湖电工新材料股份有限公司 一种无溶剂绝缘漆及其制备方法
CN110981836B (zh) * 2019-12-20 2022-09-13 广东省科学院化工研究所 一种一锅法制备二环氧化物的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0204130B8 (pt) * 2002-09-18 2021-05-25 Fund De Amparo A Pesquisa Do Estado De Sao Paulo Fapesp composição gel à base de extrato de pothomorphe umbellata, seus usos e método cosmético não-terapêutico.
BRPI0504720A (pt) * 2005-08-22 2007-05-15 Univ Sao Paulo processo de obtenção de catecol e derivados a partir de plantas do gênero pothomorphe, formulações e uso dos mesmos

Also Published As

Publication number Publication date
US20110136901A1 (en) 2011-06-09
WO2009082795A1 (en) 2009-07-09
BRPI0721725B1 (pt) 2020-02-11
BRPI0721725B8 (pt) 2021-05-25
US8673971B2 (en) 2014-03-18
EP2222624A1 (en) 2010-09-01
EP2222624A4 (en) 2012-04-18

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 11/02/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 28/12/2007 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF