BRPI0601885A - antiinflammatory and analgesic pharmaceutical composition containing n-acylhydrazenic derivatives of safrol, use, and process for their preparation - Google Patents
antiinflammatory and analgesic pharmaceutical composition containing n-acylhydrazenic derivatives of safrol, use, and process for their preparationInfo
- Publication number
- BRPI0601885A BRPI0601885A BRPI0601885-8A BRPI0601885A BRPI0601885A BR PI0601885 A BRPI0601885 A BR PI0601885A BR PI0601885 A BRPI0601885 A BR PI0601885A BR PI0601885 A BRPI0601885 A BR PI0601885A
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- derivatives
- safrol
- antiinflammatory
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
COMPOSIçãO FARMACêUTICA ANTIINFLAMATóRIA E ANALGéSICA CONTENDO DERIVADOS N-ACILIDRAZÈNICOS DO SAFROL, USO, E PROCESSO PARA SUA PREPARAçãO. São descritas novos derivados do núcleo 6-nitro-N-arilmetilideno-1,3-benzodioxola-5-carboidrazida que atuam como antiinflamatórios e analgésicos com ação no sistema nervoso central, sendo, portanto, úteis no tratamento doenças inflamatórias agudas e crónicas e hiperalgesia central em mamíferos; também são descritas composições farmacêuticas contendo os referidos compostos e processos para sua preparação.ANTI-INFLAMMATORY AND ANALGESIC PHARMACEUTICAL COMPOSITION CONTAINING N-ACYLIDRAZENIC SAFROL DERIVATIVES, USE, AND PROCESS FOR THEIR PREPARATION. New derivatives of the 6-nitro-N-arylmethylidene-1,3-benzodioxola-5-carbohydrazide nucleus that act as antiinflammatory and analgesic agents acting on the central nervous system are therefore useful in the treatment of acute and chronic inflammatory diseases and hyperalgesia. central in mammals; Also disclosed are pharmaceutical compositions containing said compounds and processes for their preparation.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0601885-8A BRPI0601885A (en) | 2006-05-15 | 2006-05-15 | antiinflammatory and analgesic pharmaceutical composition containing n-acylhydrazenic derivatives of safrol, use, and process for their preparation |
PCT/BR2007/000114 WO2007131310A1 (en) | 2006-05-15 | 2007-05-14 | Anti-inflammatory and analgesic pharmaceutical composition containing safrole n-acylhydrazone derivatives, use, and method of preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0601885-8A BRPI0601885A (en) | 2006-05-15 | 2006-05-15 | antiinflammatory and analgesic pharmaceutical composition containing n-acylhydrazenic derivatives of safrol, use, and process for their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0601885A true BRPI0601885A (en) | 2008-03-25 |
Family
ID=38693471
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0601885-8A BRPI0601885A (en) | 2006-05-15 | 2006-05-15 | antiinflammatory and analgesic pharmaceutical composition containing n-acylhydrazenic derivatives of safrol, use, and process for their preparation |
Country Status (2)
Country | Link |
---|---|
BR (1) | BRPI0601885A (en) |
WO (1) | WO2007131310A1 (en) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB921322A (en) * | 1960-05-23 | 1963-03-20 | Charles E Frosst & Company | Substituted hydrazide compounds |
EP0214158A1 (en) * | 1985-02-11 | 1987-03-18 | The Upjohn Company | Anthelmintic pyridinyl acylhydrazones, method of use and compositions |
CA2384525C (en) * | 1999-06-21 | 2007-03-06 | University Of Maryland, Baltimore | Thienylhydrazon with digitalis-like properties (positive inotropic effects) |
WO2002089745A2 (en) * | 2001-05-10 | 2002-11-14 | Cytovia, Inc. | Substituted n'-(arylcarbonyl)-benzhydrazides, n'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof |
CA2608243A1 (en) * | 2005-05-06 | 2006-11-16 | Boehringer Ingelheim International Gmbh | Acyl hydrazones for treating cardiovascular diseases |
-
2006
- 2006-05-15 BR BRPI0601885-8A patent/BRPI0601885A/en not_active Application Discontinuation
-
2007
- 2007-05-14 WO PCT/BR2007/000114 patent/WO2007131310A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2007131310A1 (en) | 2007-11-22 |
WO2007131310B1 (en) | 2008-01-31 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 9A ANUIDADE. |
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B08H | Application fees: decision cancelled |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2308 DE 31/03/2015. |
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B07D | Technical examination (opinion) related to article 229 of industrial property law |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
B07E | Notice of approval relating to section 229 industrial property law |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B06V | Preliminary requirement: requests without searches performed by other patent offices: suspension of the patent application procedure | ||
B07A | Technical examination (opinion): publication of technical examination (opinion) | ||
B09B | Decision: refusal | ||
B09B | Decision: refusal |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |