BRPI0518883A2 - self-limiting size compositions and test devices for measuring analytes in biological fluids - Google Patents
self-limiting size compositions and test devices for measuring analytes in biological fluidsInfo
- Publication number
- BRPI0518883A2 BRPI0518883A2 BRPI0518883-0A BRPI0518883A BRPI0518883A2 BR PI0518883 A2 BRPI0518883 A2 BR PI0518883A2 BR PI0518883 A BRPI0518883 A BR PI0518883A BR PI0518883 A2 BRPI0518883 A2 BR PI0518883A2
- Authority
- BR
- Brazil
- Prior art keywords
- water
- self
- biological fluids
- test devices
- analyte
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000013060 biological fluid Substances 0.000 title abstract 2
- 239000012491 analyte Substances 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000012035 limiting reagent Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/521—Single-layer analytical elements
- G01N33/523—Single-layer analytical elements the element being adapted for a specific analyte
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/61—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving triglycerides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/62—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving uric acid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/8483—Investigating reagent band
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
A test strip or electrochemical sensor for measuring the amount of an analyte in a biological fluid, e.g. the glucose content of whole blood, includes a size self-limiting reagent formulation employing an enzyme system for reaction with the analyte, the reactive system mixed into a water-soluble swellable polymer matrix containing small water-insoluble particles having a nominal size of about 0.05 to 20 μm, preferably about 1 to 10 μm. The weight ratio of the water-insoluble particles to the water-soluble swellable polymer matrix is about 1/2 to 2/1. The reagent formulation is deposited onto a non-porous substrate to form a thin layer about 6-16 μm thick, providing a rapid and stable response to application of a sample, while being insensitive to the amount of the sample.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63571104P | 2004-12-13 | 2004-12-13 | |
PCT/US2005/045235 WO2006065900A1 (en) | 2004-12-13 | 2005-12-12 | Size self-limiting compositions and test devices for measuring analytes in biological fluids |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0518883A2 true BRPI0518883A2 (en) | 2008-12-16 |
Family
ID=36095697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0518883-0A BRPI0518883A2 (en) | 2004-12-13 | 2005-12-12 | self-limiting size compositions and test devices for measuring analytes in biological fluids |
Country Status (15)
Country | Link |
---|---|
US (2) | US7964372B2 (en) |
EP (1) | EP1885869B1 (en) |
JP (1) | JP5912213B2 (en) |
CN (3) | CN103558369B (en) |
AT (1) | ATE553213T1 (en) |
BR (1) | BRPI0518883A2 (en) |
CA (1) | CA2590944C (en) |
DK (1) | DK1885869T3 (en) |
ES (1) | ES2383905T3 (en) |
HK (1) | HK1191095A1 (en) |
MX (1) | MX2007006883A (en) |
NO (1) | NO20073521L (en) |
RU (1) | RU2413002C2 (en) |
TW (1) | TW200634162A (en) |
WO (1) | WO2006065900A1 (en) |
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US20060281187A1 (en) | 2005-06-13 | 2006-12-14 | Rosedale Medical, Inc. | Analyte detection devices and methods with hematocrit/volume correction and feedback control |
US8801631B2 (en) | 2005-09-30 | 2014-08-12 | Intuity Medical, Inc. | Devices and methods for facilitating fluid transport |
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EP1949101B1 (en) * | 2005-11-14 | 2013-03-06 | Bayer HealthCare, LLC | Test sensor reagent having cellulose polymers |
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EP3369825B1 (en) * | 2007-12-10 | 2021-07-28 | Ascensia Diabetes Care Holdings AG | Porous particle reagent compositions and devices for biosensors |
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WO2010052306A1 (en) * | 2008-11-07 | 2010-05-14 | Roche Diagnostics Gmbh | Fine-grained filler substances for photometric reaction films |
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CN111007267A (en) * | 2019-12-30 | 2020-04-14 | 苏州康和顺医疗技术有限公司 | Procalcitonin (PCT) detection reagent and preparation method thereof |
CN111007264A (en) * | 2019-12-31 | 2020-04-14 | 苏州康和顺医疗技术有限公司 | Detection reagent for sialidation carbohydrate chain antigen KL-6 and preparation method thereof |
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-
2005
- 2005-12-12 RU RU2007126680/10A patent/RU2413002C2/en not_active IP Right Cessation
- 2005-12-12 AT AT05854033T patent/ATE553213T1/en active
- 2005-12-12 CA CA2590944A patent/CA2590944C/en not_active Expired - Fee Related
- 2005-12-12 ES ES05854033T patent/ES2383905T3/en active Active
- 2005-12-12 JP JP2007546857A patent/JP5912213B2/en active Active
- 2005-12-12 WO PCT/US2005/045235 patent/WO2006065900A1/en active Application Filing
- 2005-12-12 EP EP05854033A patent/EP1885869B1/en not_active Revoked
- 2005-12-12 DK DK05854033.7T patent/DK1885869T3/en active
- 2005-12-12 CN CN201310464523.7A patent/CN103558369B/en not_active Expired - Fee Related
- 2005-12-12 BR BRPI0518883-0A patent/BRPI0518883A2/en not_active IP Right Cessation
- 2005-12-12 CN CN200580042703XA patent/CN101076601B/en not_active Expired - Fee Related
- 2005-12-12 MX MX2007006883A patent/MX2007006883A/en active IP Right Grant
- 2005-12-12 CN CN2013102423576A patent/CN103305590A/en active Pending
- 2005-12-12 US US11/792,456 patent/US7964372B2/en active Active
- 2005-12-13 TW TW094143965A patent/TW200634162A/en unknown
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2007
- 2007-07-09 NO NO20073521A patent/NO20073521L/en not_active Application Discontinuation
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2011
- 2011-05-11 US US13/105,375 patent/US9982289B2/en active Active
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2014
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Also Published As
Publication number | Publication date |
---|---|
ES2383905T3 (en) | 2012-06-27 |
US9982289B2 (en) | 2018-05-29 |
NO20073521L (en) | 2007-07-09 |
CN103305590A (en) | 2013-09-18 |
RU2413002C2 (en) | 2011-02-27 |
RU2007126680A (en) | 2009-01-20 |
CN103558369A (en) | 2014-02-05 |
CN103558369B (en) | 2015-09-09 |
CA2590944A1 (en) | 2006-06-22 |
EP1885869A1 (en) | 2008-02-13 |
CN101076601B (en) | 2013-11-13 |
US20090123955A1 (en) | 2009-05-14 |
JP2008523415A (en) | 2008-07-03 |
HK1191095A1 (en) | 2014-07-18 |
DK1885869T3 (en) | 2012-07-09 |
EP1885869B1 (en) | 2012-04-11 |
US20110281287A1 (en) | 2011-11-17 |
US7964372B2 (en) | 2011-06-21 |
CA2590944C (en) | 2016-02-02 |
MX2007006883A (en) | 2007-08-03 |
JP5912213B2 (en) | 2016-04-27 |
TW200634162A (en) | 2006-10-01 |
CN101076601A (en) | 2007-11-21 |
ATE553213T1 (en) | 2012-04-15 |
WO2006065900A1 (en) | 2006-06-22 |
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