BRPI0518809A2 - ovulation modulation - Google Patents

ovulation modulation

Info

Publication number
BRPI0518809A2
BRPI0518809A2 BRPI0518809-1A BRPI0518809A BRPI0518809A2 BR PI0518809 A2 BRPI0518809 A2 BR PI0518809A2 BR PI0518809 A BRPI0518809 A BR PI0518809A BR PI0518809 A2 BRPI0518809 A2 BR PI0518809A2
Authority
BR
Brazil
Prior art keywords
ovulation
modulation
gdf
molecules
domain
Prior art date
Application number
BRPI0518809-1A
Other languages
Portuguese (pt)
Inventor
Jennifer Lee Juengel
Kenneth Pattrick Mcnatty
Loyd Gary Moore
Robert Syndecombe Bower
Original Assignee
Agres Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NZ53694304A external-priority patent/NZ536943A/en
Application filed by Agres Ltd filed Critical Agres Ltd
Publication of BRPI0518809A2 publication Critical patent/BRPI0518809A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

MODULAÇçO DA OVULAÇçO. A presente invenção é dirigida à identificação de um domínio inédito de importância funcional nas moléculas de GDF-9 e GDF-9B e aos peptídeos e anticorpos que interagem com o domínio para modular a atividade biológica dessas moléculas a fim de alterar a função ovariana a taxa de ovulação de mamíferos.OVULATION MODULATION. The present invention is directed to the identification of an unpublished domain of functional importance in GDF-9 and GDF-9B molecules and the peptides and antibodies that interact with the domain to modulate the biological activity of these molecules in order to alter the ovarian function at the rate. of ovulation of mammals.

BRPI0518809-1A 2004-12-02 2005-12-02 ovulation modulation BRPI0518809A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NZ53694304A NZ536943A (en) 2004-12-02 2004-12-02 Modulation of ovulation
NZ53903905 2005-03-24
NZ54117005 2005-07-08
PCT/NZ2005/000313 WO2006059913A1 (en) 2004-12-02 2005-12-02 Modulation of ovulation

Publications (1)

Publication Number Publication Date
BRPI0518809A2 true BRPI0518809A2 (en) 2008-12-09

Family

ID=36565307

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0518809-1A BRPI0518809A2 (en) 2004-12-02 2005-12-02 ovulation modulation

Country Status (6)

Country Link
EP (1) EP1819722A4 (en)
JP (1) JP2008521891A (en)
AU (1) AU2005310356A1 (en)
BR (1) BRPI0518809A2 (en)
CA (1) CA2589898A1 (en)
WO (1) WO2006059913A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006130022A1 (en) * 2005-05-30 2006-12-07 Agresearch Limited Modulation of ovulation by agonists and antagonists of bmprii
EP2228070B1 (en) 2005-07-18 2016-09-07 Adelaide Research & Innovation Pty Ltd Modulation of granulosa cell apoptosis
BRPI0706173C1 (en) * 2007-11-23 2011-02-22 Brasil Pesquisa Agropec method for mass identification of animals with increased prolificacy
WO2019213690A1 (en) 2018-05-09 2019-11-14 Monash University Agentand method forenhancing fertility

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821056A (en) * 1993-01-12 1998-10-13 The Johns Hopkins University School Of Medicine Growth differentiation factor-9
US6030617A (en) * 1993-01-12 2000-02-29 The Johns Hopkins University School Of Medicine Use of growth differentiation factor-9 (GDF-9) to inhibit oocyte maturation
NZ519330A (en) * 2002-05-30 2004-12-24 George Henry Davis New sequences for altering mammalian ovarian function and ovulation rate

Also Published As

Publication number Publication date
AU2005310356A1 (en) 2006-06-08
WO2006059913A1 (en) 2006-06-08
CA2589898A1 (en) 2006-06-08
EP1819722A1 (en) 2007-08-22
WO2006059913A9 (en) 2008-05-22
EP1819722A4 (en) 2009-09-09
JP2008521891A (en) 2008-06-26

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired