BRPI0517460A - análogos canabinóides eficazes de administração oral - Google Patents
análogos canabinóides eficazes de administração oralInfo
- Publication number
- BRPI0517460A BRPI0517460A BRPI0517460-0A BRPI0517460A BRPI0517460A BR PI0517460 A BRPI0517460 A BR PI0517460A BR PI0517460 A BRPI0517460 A BR PI0517460A BR PI0517460 A BRPI0517460 A BR PI0517460A
- Authority
- BR
- Brazil
- Prior art keywords
- useful
- effective
- effective oral
- oral cannabinoid
- cannabinoid analogues
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
ANALOGOS CANABINóIDES EFICAZES DE ADMINISTRAçãO ORAL. A presente invenção está relacionada a ligantes oralmente eficazes de canabinóide periférico do mesmo, receptor CB~ 2~, especialmente derivados de (+) - <244> - pineno, e às suas composições farmacêuticas, as quais são úteis para a prevenção, alívio ou tratamento de distúrbios autoimunes neurodegenerativos, em particular esclerose múltipla e sintomas associados. Os métodos da invenção são úteis quando o ingrediente ativo é administrado sozinho ou em combinação com modalidades terapêuticas existentes. As composições são administradas por via oral.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62071604P | 2004-10-22 | 2004-10-22 | |
PCT/IL2005/000231 WO2006043260A2 (en) | 2004-10-22 | 2005-02-24 | Orally effective cannabinoid analogs |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0517460A true BRPI0517460A (pt) | 2008-10-07 |
Family
ID=36203335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0517460-0A BRPI0517460A (pt) | 2004-10-22 | 2005-02-24 | análogos canabinóides eficazes de administração oral |
Country Status (10)
Country | Link |
---|---|
US (1) | US20090068143A1 (pt) |
EP (1) | EP1802293A4 (pt) |
JP (1) | JP2008517901A (pt) |
KR (1) | KR20070083903A (pt) |
CN (1) | CN101076324A (pt) |
AU (1) | AU2005297249A1 (pt) |
BR (1) | BRPI0517460A (pt) |
CA (1) | CA2584550A1 (pt) |
WO (1) | WO2006043260A2 (pt) |
ZA (1) | ZA200703517B (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010535238A (ja) * | 2007-07-30 | 2010-11-18 | オールトランツ インコーポレイティド | カンナビジオールのプロドラッグ、カンナビジオールのプロドラッグを含む組成物及びその使用方法 |
EP2415765A4 (en) | 2009-03-30 | 2012-08-15 | Astellas Pharma Inc | PYRIMIDINE COMPOUND |
US9763992B2 (en) | 2014-02-13 | 2017-09-19 | Father Flanagan's Boys' Home | Treatment of noise induced hearing loss |
WO2015200049A1 (en) | 2014-06-26 | 2015-12-30 | Island Breeze Systems Ca, Llc | Mdi related products and methods of use |
WO2017185038A1 (en) | 2016-04-22 | 2017-10-26 | Receptor Life Sciences | Fast-acting plant-based medicinal compounds and nutritional supplements |
EA201892396A1 (ru) | 2016-12-02 | 2019-04-30 | Ресептор Лайф Сайенсиз, Инк. | Быстродействующие растительные лекарственные соединения и биологически активные добавки |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4208351A (en) * | 1976-11-10 | 1980-06-17 | Eli Lilly And Company | Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor |
IL55274A (en) * | 1978-08-02 | 1982-08-31 | Yissum Res Dev Co | 4-(2,6-dihydroxy-4-(dimethylheptyl)phenyl)substituted 2-pinen-10-ol and pinane derivatives,their preparation and pharmaceutical compositions comprising them |
US5434295A (en) * | 1994-02-07 | 1995-07-18 | Yissum Research Development Company | Neuroprotective pharmaceutical compositions of 4-phenylpinene derivatives and certain novel 4-phenylpinene compounds |
AU785033B2 (en) * | 1999-10-18 | 2006-08-31 | University Of Connecticut, The | Novel bicyclic cannabinoid agonists for the cannabinoid receptor |
JP2005523259A (ja) * | 2002-01-31 | 2005-08-04 | ファーモス コーポレイション | 二環式cb2カンナビノイド受容体リガンド |
IL147941A0 (en) * | 2002-01-31 | 2002-08-14 | Pharmos Corp | Bicyclic cb2 cannabinoid receptor ligands |
-
2005
- 2005-02-24 CA CA002584550A patent/CA2584550A1/en not_active Abandoned
- 2005-02-24 US US11/577,349 patent/US20090068143A1/en not_active Abandoned
- 2005-02-24 BR BRPI0517460-0A patent/BRPI0517460A/pt not_active IP Right Cessation
- 2005-02-24 EP EP05709127A patent/EP1802293A4/en not_active Withdrawn
- 2005-02-24 ZA ZA200703517A patent/ZA200703517B/xx unknown
- 2005-02-24 AU AU2005297249A patent/AU2005297249A1/en not_active Abandoned
- 2005-02-24 JP JP2007537472A patent/JP2008517901A/ja not_active Abandoned
- 2005-02-24 KR KR1020077009984A patent/KR20070083903A/ko not_active Application Discontinuation
- 2005-02-24 WO PCT/IL2005/000231 patent/WO2006043260A2/en active Application Filing
- 2005-02-24 CN CNA2005800428013A patent/CN101076324A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1802293A2 (en) | 2007-07-04 |
ZA200703517B (en) | 2008-08-27 |
AU2005297249A1 (en) | 2006-04-27 |
WO2006043260A3 (en) | 2006-05-26 |
CA2584550A1 (en) | 2006-04-27 |
WO2006043260A2 (en) | 2006-04-27 |
CN101076324A (zh) | 2007-11-21 |
JP2008517901A (ja) | 2008-05-29 |
KR20070083903A (ko) | 2007-08-24 |
US20090068143A1 (en) | 2009-03-12 |
EP1802293A4 (en) | 2009-04-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 3A, 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012. |