BRPI0514445A - métodos para cicatrizar feridas administrando il-18 humano - Google Patents

métodos para cicatrizar feridas administrando il-18 humano

Info

Publication number
BRPI0514445A
BRPI0514445A BRPI0514445-0A BRPI0514445A BRPI0514445A BR PI0514445 A BRPI0514445 A BR PI0514445A BR PI0514445 A BRPI0514445 A BR PI0514445A BR PI0514445 A BRPI0514445 A BR PI0514445A
Authority
BR
Brazil
Prior art keywords
methods
healing wounds
wounds
human
administering human
Prior art date
Application number
BRPI0514445-0A
Other languages
English (en)
Inventor
Judithann Lee
Kimberly A Dede
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of BRPI0514445A publication Critical patent/BRPI0514445A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

MéTODOS PARA CICATRIZAR FERIDAS ADMINISTRANDO IL-18 HUMANO A presente invenção refere-se genericamente ao uso de IL-18 humano, também conhecida como fator indutor de interferon-y (IGIF), no tratamento de feridas da pele, feridas cirúrgicas, úlceras das pernas, úlceras diabéticas, mucosite, e lesão pulmonar.
BRPI0514445-0A 2004-08-20 2005-08-18 métodos para cicatrizar feridas administrando il-18 humano BRPI0514445A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60301204P 2004-08-20 2004-08-20
PCT/US2005/029358 WO2006023623A2 (en) 2004-08-20 2005-08-18 Methods of healing wounds by administering human il-18

Publications (1)

Publication Number Publication Date
BRPI0514445A true BRPI0514445A (pt) 2008-06-10

Family

ID=35968167

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0514445-0A BRPI0514445A (pt) 2004-08-20 2005-08-18 métodos para cicatrizar feridas administrando il-18 humano

Country Status (24)

Country Link
US (1) US7595039B2 (pt)
EP (2) EP2161032B1 (pt)
JP (1) JP4912306B2 (pt)
KR (1) KR20070050924A (pt)
CN (1) CN101039696B (pt)
AT (2) ATE426410T1 (pt)
AU (1) AU2005277404A1 (pt)
BR (1) BRPI0514445A (pt)
CA (1) CA2577777A1 (pt)
CY (1) CY1108991T1 (pt)
DE (1) DE602005013542D1 (pt)
DK (1) DK1793859T3 (pt)
ES (2) ES2322605T3 (pt)
HK (1) HK1109054A1 (pt)
IL (1) IL181286A0 (pt)
MX (1) MX2007002134A (pt)
NO (1) NO20071238L (pt)
NZ (1) NZ552837A (pt)
PL (1) PL1793859T3 (pt)
PT (1) PT1793859E (pt)
RU (1) RU2387455C2 (pt)
SI (1) SI1793859T1 (pt)
WO (1) WO2006023623A2 (pt)
ZA (1) ZA200700524B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110032012A (ko) * 2000-02-10 2011-03-29 아보트 러보러터리즈 사람 인터류킨-１８에 결합하는 항체 및 이를 제조하고 사용하는 방법
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
US9925246B2 (en) 2011-06-13 2018-03-27 Neumedicines, Inc. Mitigation of cutaneous injury with IL-12
NZ717671A (en) * 2013-09-05 2022-07-01 Ab2 Bio Sa Il-18 binding protein (il-18bp) in inflammatory diseases
BR112017017076A2 (pt) 2015-03-05 2018-04-10 Ab2 Bio Sa inibidor de il-18, anticorpo, métodos para o tratamento de uma doença ou um distúrbio associado a il-18 em um indivíduo, para determinar a quantidade de il-18 livre em uma amostra ou in situ, para diagnosticar uma predisposição a uma doença ou um distúrbio associado a il-18, para monitorar doença residual mínima em um paciente que segue o tratamento com o inibidor de il-18 ou a composição e para prever uma resposta de um paciente a um tratamento com o inibidor de il-18 ou composição, e, kit diagnóstico para detectar il-18 livre.

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69519454T2 (de) 1994-07-14 2001-05-03 Hayashibara Biochem Lab Protein, das Interferon-Gamma Herstellung induziert und monoklonaler Antikörper dagegen
TW581771B (en) 1994-11-15 2004-04-01 Hayashibara Biochem Lab Recombinant production of a polypeptide for inducing interferon-gamma production, and monoclonal antibody against the polypeptide
JP4004088B2 (ja) 1995-09-26 2007-11-07 株式会社林原生物化学研究所 免疫担当細胞においてインターフェロン−γの産生を誘導する蛋白質
US5680795A (en) 1995-07-05 1997-10-28 Norco Inc. Mechanical drive assembly incorporating counter-spring biassed radially-adjustable rollers
JP4024366B2 (ja) * 1996-11-29 2007-12-19 株式会社林原生物化学研究所 ポリペプチド
TWI227136B (en) * 1998-05-21 2005-02-01 Smithkline Beecham Corp Novel pharmaceutical composition for the prevention and/or treatment of cancer
EP1296707A4 (en) * 2000-06-02 2004-03-17 Smithkline Beecham Corp METHODS OF TREATING VIRAL DISEASES WITH IL-18 AND IL-18 COMBINATIONS
EP1292697B1 (en) * 2000-06-15 2009-07-22 SmithKline Beecham Corporation Method for preparing a physiologically active il-18 polypeptide
US7098373B2 (en) * 2001-07-12 2006-08-29 Hitoshi Mizutani IL-18 transgenic animal
SI2298338T1 (sl) 2002-09-16 2012-11-30 Agennix Inc Laktoferinski sestavki in postopki za zdravljenjekožnih ran
EP1572228A4 (en) * 2002-09-19 2009-03-04 Centocor Inc METHOD FOR INDUCING MATURATION OF DENDRITIC CELLS AND USES THEREOF
WO2005018542A2 (en) * 2003-07-10 2005-03-03 Agennix Incorporated Use of lactoferrin in prophylaxis against infection and/or inflammation in immunosuppressed subjects

Also Published As

Publication number Publication date
EP1793859A4 (en) 2008-02-13
JP2008510709A (ja) 2008-04-10
RU2007110166A (ru) 2008-09-27
CN101039696B (zh) 2011-08-17
CA2577777A1 (en) 2006-03-02
HK1109054A1 (en) 2008-05-30
ES2322605T3 (es) 2009-06-23
KR20070050924A (ko) 2007-05-16
PT1793859E (pt) 2009-06-04
EP2161032B1 (en) 2011-09-28
ATE526057T1 (de) 2011-10-15
PL1793859T3 (pl) 2009-08-31
ATE426410T1 (de) 2009-04-15
IL181286A0 (en) 2007-07-04
NO20071238L (no) 2007-05-14
US20060039892A1 (en) 2006-02-23
CY1108991T1 (el) 2014-07-02
ES2372728T3 (es) 2012-01-25
ZA200700524B (en) 2008-05-28
EP1793859A2 (en) 2007-06-13
WO2006023623A3 (en) 2006-08-24
NZ552837A (en) 2009-09-25
WO2006023623A2 (en) 2006-03-02
EP2161032A2 (en) 2010-03-10
US7595039B2 (en) 2009-09-29
DK1793859T3 (da) 2009-06-22
AU2005277404A1 (en) 2006-03-02
CN101039696A (zh) 2007-09-19
DE602005013542D1 (de) 2009-05-07
RU2387455C2 (ru) 2010-04-27
SI1793859T1 (sl) 2009-06-30
EP1793859B1 (en) 2009-03-25
EP2161032A3 (en) 2010-07-28
MX2007002134A (es) 2007-09-14
JP4912306B2 (ja) 2012-04-11

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: GLAXOSMITHKLINE LLC (US)

Free format text: NOME ALTERADO DE: SMITHKLINE BEECHAM CORPORATION

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE A 7A ANUIDADE.