BRPI0513066A - distribution system - Google Patents

distribution system

Info

Publication number
BRPI0513066A
BRPI0513066A BRPI0513066-2A BRPI0513066A BRPI0513066A BR PI0513066 A BRPI0513066 A BR PI0513066A BR PI0513066 A BRPI0513066 A BR PI0513066A BR PI0513066 A BRPI0513066 A BR PI0513066A
Authority
BR
Brazil
Prior art keywords
delivery system
vaginal cavity
distribution system
emulsion
phase emulsion
Prior art date
Application number
BRPI0513066-2A
Other languages
Portuguese (pt)
Inventor
Robert C Cuca
Thomas C Riley
R Saul Levinson
Original Assignee
Drugtech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drugtech Corp filed Critical Drugtech Corp
Publication of BRPI0513066A publication Critical patent/BRPI0513066A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/42—Gynaecological or obstetrical instruments or methods
    • A61B2017/4216—Operations on uterus, e.g. endometrium

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

SISTEMA DE DISTRIBUIçãO. A presente invenção refere-se a um sistema de distribuição farmacêutico que libera um agente ativo em uma maneira controlada por um período prolongado na cavidade vaginal para tratar ou curar doenças associadas com a cavidade vaginal ou áreas proximais. O sistema de distribuição inclui um aplicador que é composto de uma emulsão de alta fase interna, permitindo que o sistema de distribuição adira nas superfícies de mucosa do corpo, primariamente o revestimento da cavidade vaginal. O sistema de distribuição pode manter a emulsão de alta fase interna em uma temperatura de 30 C (86 F) por pelo menos um mês, sem decomposição ou instabilidade da emulsão.DISTRIBUTION SYSTEM. The present invention relates to a pharmaceutical delivery system which releases an active agent in a controlled manner for an extended period in the vaginal cavity to treat or cure diseases associated with the vaginal cavity or proximal areas. The delivery system includes an applicator that is composed of a high internal phase emulsion, allowing the delivery system to adhere to the mucosal surfaces of the body, primarily the lining of the vaginal cavity. The dispensing system may maintain the internal high phase emulsion at a temperature of 30 ° C (86 ° F) for at least one month without emulsion decomposition or instability.

BRPI0513066-2A 2004-07-08 2005-07-08 distribution system BRPI0513066A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58627304P 2004-07-08 2004-07-08
PCT/US2004/022058 WO2006016869A1 (en) 2004-07-08 2004-07-08 Delivery system
PCT/US2005/024200 WO2006014572A1 (en) 2004-07-08 2005-07-08 Delivery system

Publications (1)

Publication Number Publication Date
BRPI0513066A true BRPI0513066A (en) 2008-04-22

Family

ID=35787422

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513066-2A BRPI0513066A (en) 2004-07-08 2005-07-08 distribution system

Country Status (13)

Country Link
EP (1) EP1765452A4 (en)
CN (2) CN1771023A (en)
AU (2) AU2004100776A4 (en)
BR (1) BRPI0513066A (en)
CA (1) CA2572919A1 (en)
CZ (1) CZ15068U1 (en)
ES (1) ES1060042Y (en)
FR (1) FR2872702B3 (en)
MX (2) MXPA04007681A (en)
NL (1) NL1026978C1 (en)
NZ (1) NZ552406A (en)
RU (1) RU2379027C2 (en)
WO (2) WO2006016869A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2008651A1 (en) * 2007-06-26 2008-12-31 Drug Delivery Solutions Limited A bioerodible patch
EP2100632A1 (en) 2008-03-11 2009-09-16 Pantarhei Devices B.V. Applicator device for body cavity
US8308678B2 (en) 2008-09-23 2012-11-13 Mcneil-Ppc, Inc. Pre-filled applicator device
EP2359750A1 (en) 2010-02-15 2011-08-24 Delphi Bioscience B.V. Screening device with valve
FR2968004B1 (en) 2010-11-29 2013-06-28 Sojasun Technologies BIODEGRADABLE NATURAL FILMS BASED ON CO-PRODUCTS FROM INDUSTRIAL PROCESSES FOR SEED TREATMENT.
RU2538703C2 (en) * 2013-03-12 2015-01-10 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Pharmaceutical composition for treating vaginal candidiasis and method for preparing it
CN108310606A (en) * 2015-09-18 2018-07-24 赵坚 A kind of drug delivery device of external use gynaecological medicine
KR102509239B1 (en) * 2018-06-11 2023-03-14 더 프록터 앤드 갬블 캄파니 Methods and applicators for treating vaginal conditions
CN112716796B (en) * 2018-12-11 2022-07-08 管云 Power-assisted medicine dispensing device

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636202A (en) * 1984-07-27 1987-01-13 Syntex (U.S.A.) Inc. Medicament applicator with plunger assembly and automatically-openable closure therefor
US5266329A (en) * 1985-10-31 1993-11-30 Kv Pharmaceutical Company Vaginal delivery system
US5536743A (en) * 1988-01-15 1996-07-16 Curatek Pharmaceuticals Limited Partnership Intravaginal treatment of vaginal infections with buffered metronidazole compositions
ES2133090B1 (en) * 1997-02-21 2000-04-01 Uriach & Cia Sa J NEW APPLICATOR FOR THE ADMINISTRATION OF SEMI-SOLID MEDICATIONS.
US6403576B1 (en) * 1998-08-24 2002-06-11 The United States Of America As Represented By The Secretary Of The Navy Antifungal and antiparasitic compounds
US20040047910A1 (en) * 2000-07-07 2004-03-11 Christian Beckett Suppository and composition comprising at least one polyethylene glycol

Also Published As

Publication number Publication date
WO2006016869A1 (en) 2006-02-16
ES1060042Y (en) 2005-11-01
MX2007000109A (en) 2007-03-26
FR2872702B3 (en) 2006-06-02
CN1771023A (en) 2006-05-10
AU2005269844A1 (en) 2006-02-09
CN102188375A (en) 2011-09-21
MXPA04007681A (en) 2006-01-12
WO2006014572A1 (en) 2006-02-09
CA2572919A1 (en) 2006-02-09
RU2007104782A (en) 2008-08-20
RU2379027C2 (en) 2010-01-20
EP1765452A1 (en) 2007-03-28
EP1765452A4 (en) 2012-11-28
NL1026978C1 (en) 2006-01-10
NZ552406A (en) 2010-07-30
CZ15068U1 (en) 2005-01-31
FR2872702A3 (en) 2006-01-13
ES1060042U (en) 2005-07-16
AU2004100776A4 (en) 2004-11-18

Similar Documents

Publication Publication Date Title
BRPI0513066A (en) distribution system
BRPI0513673B8 (en) method for producing a drug to increase the efficacy and transport of enterally administered biologically active compounds, and pharmaceutical composition
BR0306513A (en) medicine buffer
BRPI0412496A (en) delivery of an active drug to the back of the eye by subconjunctival or periocular delivery of a prodrug
BR9815442A (en) Targeted therapeutic release of vitamin D compounds
BRPI0518266A2 (en) modified-release oral medicinal product of at least one active ingredient in multi-capsule form
BR0005299A (en) Compounds for the treatment of female sexual dysfunction
BRPI0903464B8 (en) aqueous formulation of a therapeutic agent and method of creating a drug delivery device
BR0209658A (en) 4-Amino-5-phenyl-7-1-cyclobutyl-pyrrolo [2,3-d] pyrimidine derivatives
BR0014929A (en) Drug delivery device, and process for delivering a pharmaceutically active agent to a target tissue within a body
BRPI0603073A (en) Method for delivering drugs to micro-jet propelled tissue
BR0015974A (en) Use of levetiracetam, pharmaceutical composition, use of a pharmaceutical composition and methods to treat a patient administered with an amount of at least one compound and a disease and to selectively potentiate the therapeutic effect of a compound
BR0316157A (en) 4-Amino-5-phenyl-7-cyclohexyl-pyrrolo [2,3-d] pyrimidine derivatives
BR0306501A (en) Method for use and production of a medicated buffer
MX2010004373A (en) Non-aqueous water-miscible materials as vehicles for drug delivery.
BR9912179A (en) Neuroprotective composition for the prevention and / or treatment of nervous and behavioral changes due to states of anxiety or depression
BR112012030641B8 (en) Uses and compositions for oral pharmaceutical therapy
BRPI0608334A2 (en) use of a powdered clobetasol formulation for the treatment of psoriasis
HRP20192246T1 (en) Marker for acid sphingomyelinase disorders and uses thereof
BR112017016087A2 (en) adipose joint cushion formulations and methods of use thereof
BRPI0414500A (en) pharmaceutical formulation composition to treat a vaginal infection, and methods to treat a vaginal infection, to stabilize a clindamycin formulation, to treat or prevent a recurrence of a vaginal infection in a patient and to treat vaginal conditions
BR112015000321A2 (en) Laquinimod formulations without alkalizing agent
BR0014946A (en) Use of dipyridamole or mopidamol in the manufacture of a drug for the treatment and prevention of fibrin-dependent microcirculatory disorders
BR112018000039A2 (en) single use release device
BRPI0607172A2 (en) method for administering at least one pharmaceutically active substance to a patient, combining medicaments and using at least one pharmaceutically active substance for the manufacture of a combination of medicaments

Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 7A ANUIDADE.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.