BRPI0507509A - utilização de derivados de indolizina 1,2,3 substituìdos, inibidores dos fgfs, para o preparo de medicamentos úteis para o tratamento de angiogênese patológica coroidiana - Google Patents

utilização de derivados de indolizina 1,2,3 substituìdos, inibidores dos fgfs, para o preparo de medicamentos úteis para o tratamento de angiogênese patológica coroidiana

Info

Publication number
BRPI0507509A
BRPI0507509A BRPI0507509-2A BRPI0507509A BRPI0507509A BR PI0507509 A BRPI0507509 A BR PI0507509A BR PI0507509 A BRPI0507509 A BR PI0507509A BR PI0507509 A BRPI0507509 A BR PI0507509A
Authority
BR
Brazil
Prior art keywords
alk
alkyl
alkoxy
coor
preparation
Prior art date
Application number
BRPI0507509-2A
Other languages
English (en)
Inventor
Alain Badorc
Francoise Bono
Marie-Francoise Bordes
Jean-Michel Foidart
Nathalie Guillo
Agn S Noel
Jean-Marie Rakic
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of BRPI0507509A publication Critical patent/BRPI0507509A/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)

Abstract

UTILIZAçãO DE DERIVADOS DE INDOLIZINA 1,2,3 SUBSTITUìDOS, INIBIDORES DOS FGFs, PARA O PREPARO DE MEDICAMENTOS úTEIS PARA O TRATAMENTO DE ANGIOGêNESE PATOLóGICA COROIDIANA. A presente invenção refere-se à utilização de derivados de indolizina 1,2,3, substituídos para o preparo de medicamentos úteis para o tratamento de doenças ligadas a uma angiogênese patológica coroidiana derivados correspondentes à seguinte fórmula geral (I).
BRPI0507509-2A 2004-02-05 2005-02-04 utilização de derivados de indolizina 1,2,3 substituìdos, inibidores dos fgfs, para o preparo de medicamentos úteis para o tratamento de angiogênese patológica coroidiana BRPI0507509A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0401094A FR2865934B1 (fr) 2004-02-05 2004-02-05 Utilisation de derives d'indolizine 1,2,3 substitues, inhibiteurs des fgfs, pour la preparation de medicaments utiles pour le traitement de maladies liees a une angiogenese pathologique choroidienne
PCT/FR2005/000253 WO2005082457A2 (fr) 2004-02-05 2005-02-04 Utilisation de derives d’indolizine 1,2,3 substitues pour le traitement de maladies liees à une angiogenese pathologique choroïdienne.

Publications (1)

Publication Number Publication Date
BRPI0507509A true BRPI0507509A (pt) 2007-06-26

Family

ID=34778525

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507509-2A BRPI0507509A (pt) 2004-02-05 2005-02-04 utilização de derivados de indolizina 1,2,3 substituìdos, inibidores dos fgfs, para o preparo de medicamentos úteis para o tratamento de angiogênese patológica coroidiana

Country Status (21)

Country Link
US (1) US8034828B2 (pt)
EP (1) EP1713543B1 (pt)
JP (1) JP5268258B2 (pt)
KR (1) KR101199730B1 (pt)
CN (1) CN1917922B (pt)
AT (1) ATE448003T1 (pt)
AU (1) AU2005216671B2 (pt)
BR (1) BRPI0507509A (pt)
CA (1) CA2553895C (pt)
CY (1) CY1109669T1 (pt)
DE (1) DE602005017581D1 (pt)
DK (1) DK1713543T3 (pt)
ES (1) ES2335900T3 (pt)
FR (1) FR2865934B1 (pt)
HK (1) HK1101065A1 (pt)
HR (1) HRP20100030T1 (pt)
IL (1) IL177088A (pt)
PL (1) PL1713543T3 (pt)
PT (1) PT1713543E (pt)
SI (1) SI1713543T1 (pt)
WO (1) WO2005082457A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
JP2010505962A (ja) 2006-10-09 2010-02-25 武田薬品工業株式会社 キナーゼ阻害剤
JP2010505961A (ja) * 2006-10-09 2010-02-25 タケダ サン ディエゴ インコーポレイテッド キナーゼ阻害剤
EP2270043A1 (en) 2009-07-03 2011-01-05 Sanofi-Aventis Extracellular allosteric inhibitor binding domain from a tyrosine kinase receptor
FR2962438B1 (fr) 2010-07-06 2012-08-17 Sanofi Aventis Derives d'indolizines, procedes de preparation et application en therapeutique
FR2962437B1 (fr) 2010-07-06 2012-08-17 Sanofi Aventis Derives d'imidazopyridine, leur procede de preparation et leur application en therapeutique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2838123B1 (fr) * 2002-04-04 2005-06-10 Sanofi Synthelabo Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf

Also Published As

Publication number Publication date
CA2553895C (fr) 2013-04-02
FR2865934B1 (fr) 2006-05-05
CY1109669T1 (el) 2014-08-13
PT1713543E (pt) 2009-12-15
AU2005216671B2 (en) 2010-09-16
KR20070034986A (ko) 2007-03-29
DE602005017581D1 (de) 2009-12-24
KR101199730B1 (ko) 2012-11-08
WO2005082457A2 (fr) 2005-09-09
ES2335900T3 (es) 2010-04-06
US20090030034A1 (en) 2009-01-29
WO2005082457A3 (fr) 2005-11-10
ATE448003T1 (de) 2009-11-15
EP1713543B1 (fr) 2009-11-11
HK1101065A1 (pt) 2007-10-05
IL177088A (en) 2010-12-30
HRP20100030T1 (hr) 2010-03-31
CA2553895A1 (fr) 2005-09-09
PL1713543T3 (pl) 2010-04-30
DK1713543T3 (da) 2010-03-22
FR2865934A1 (fr) 2005-08-12
EP1713543A2 (fr) 2006-10-25
CN1917922B (zh) 2013-06-12
SI1713543T1 (sl) 2010-03-31
CN1917922A (zh) 2007-02-21
AU2005216671A1 (en) 2005-09-09
IL177088A0 (en) 2006-12-10
JP2007520534A (ja) 2007-07-26
JP5268258B2 (ja) 2013-08-21
US8034828B2 (en) 2011-10-11

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 31/437 (2006.01), A61P 35/00 (2006.01)