BRPI0417231A - método para qualificar estado da doença de chagas em um paciente, kit, produto do software, biomolécula purificada, e, métodos para qualificar estado da doença de chagas e para monitorar o curso de progressão da doença de chagas em um paciente - Google Patents
método para qualificar estado da doença de chagas em um paciente, kit, produto do software, biomolécula purificada, e, métodos para qualificar estado da doença de chagas e para monitorar o curso de progressão da doença de chagas em um pacienteInfo
- Publication number
- BRPI0417231A BRPI0417231A BRPI0417231-0A BRPI0417231A BRPI0417231A BR PI0417231 A BRPI0417231 A BR PI0417231A BR PI0417231 A BRPI0417231 A BR PI0417231A BR PI0417231 A BRPI0417231 A BR PI0417231A
- Authority
- BR
- Brazil
- Prior art keywords
- chagas disease
- patient
- qualifying
- disease status
- progression
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6893—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for protozoa
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4716—Complement proteins, e.g. anaphylatoxin, C3a, C5a
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/775—Apolipopeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
Abstract
"MéTODO PARA QUALIFICAR ESTADO DA DOENçA DE CHAGAS EM UM PACIENTE KIT, PRODUTO DO SOFTWARE, BIOMOLéCULA PURIFICADA, E, MéTODOS PARA QUALIFICAR ESTADO DA DOENçA DE CHAGAS E PARA MONITORAR O CURSO DE PROGRESSãO DA DOENçA DE CHAGAS EM UM PACIENTE". A presente invenção fornece biomarcadores com base em proteína e combinações de biomarcador que são úteis na qualificação do estado da doença de Chagas em um paciente. Em particular, os biomarcadores desta invenção são úteis para a classificação de uma amostra de paciente como infectada com doença de Chagas ou não infectado. Os biomarcadores podem ser detectados pela espectrometria de massa SELDI.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52715303P | 2003-12-05 | 2003-12-05 | |
US56509304P | 2004-04-22 | 2004-04-22 | |
US62551904P | 2004-11-06 | 2004-11-06 | |
PCT/US2004/040990 WO2005055812A2 (en) | 2003-12-05 | 2004-12-06 | Serum biomarkers for chagas disease |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0417231A true BRPI0417231A (pt) | 2007-04-17 |
Family
ID=34682161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0417231-0A BRPI0417231A (pt) | 2003-12-05 | 2004-12-06 | método para qualificar estado da doença de chagas em um paciente, kit, produto do software, biomolécula purificada, e, métodos para qualificar estado da doença de chagas e para monitorar o curso de progressão da doença de chagas em um paciente |
Country Status (6)
Country | Link |
---|---|
US (2) | US8043825B2 (pt) |
EP (1) | EP1718763B1 (pt) |
AT (1) | ATE525478T1 (pt) |
BR (1) | BRPI0417231A (pt) |
CA (1) | CA2547861A1 (pt) |
WO (1) | WO2005055812A2 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007012052A1 (en) * | 2005-07-20 | 2007-01-25 | Medical College Of Georgia Research Institute | Use of protein profiles in disease diagnosis and treatment |
WO2007070809A2 (en) * | 2005-12-12 | 2007-06-21 | Mcgill University | Biomarkers for babesia |
WO2009059409A1 (en) * | 2007-11-05 | 2009-05-14 | The Royal Institution For The Advancement Of Learning/Mcgill University | Biomarkers for visceral leishmaniasis |
JP2009244154A (ja) * | 2008-03-31 | 2009-10-22 | Nationa Hospital Organization | 老化、および血管障害を伴う疾患の検定のための組成物、キットおよび方法 |
US20110195404A1 (en) * | 2010-02-10 | 2011-08-11 | Selinfreund Richard H | Systems and methods for determining calcium levels |
US9918989B2 (en) * | 2013-07-12 | 2018-03-20 | The Regents Of The University Of California | Combination therapies for malaria |
CN108393195B (zh) * | 2018-02-06 | 2020-03-20 | 常州大学 | 一种湿法脱除pm2.5装置 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4705751A (en) * | 1983-12-28 | 1987-11-10 | Wisconsin Alumni Research Foundation | Process for preparation of multimeric plasma fibronectin |
US5281522A (en) * | 1988-09-15 | 1994-01-25 | Adeza Biomedical Corporation | Reagents and kits for determination of fetal fibronectin in a vaginal sample |
SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
US6283761B1 (en) | 1992-09-08 | 2001-09-04 | Raymond Anthony Joao | Apparatus and method for processing and/or for providing healthcare information and/or healthcare-related information |
CA2512290C (en) | 1993-05-28 | 2010-02-02 | Baylor College Of Medicine | Method and apparatus for desorption and ionization of analytes |
US5786156A (en) * | 1993-12-21 | 1998-07-28 | Perimmune Holdings, Inc. | Immunoreactive peptides of APO(A) |
US6107045A (en) * | 1994-06-30 | 2000-08-22 | Oklahoma Medical Research Foundation | Antibodies to lipoproteins and apolipoproteins and methods of use thereof |
ATE294868T1 (de) * | 1994-09-14 | 2005-05-15 | Baylor College Medicine | Impfstoff gegen streptokokkeninfektionen der gruppe a |
US6156546A (en) * | 1997-05-16 | 2000-12-05 | Washington State University Research Foundation | Identification and molecular cloning of a gene encoding a fibronectin binding protein (CadF) from Campylobacter coli and Campylobacter jejuni |
NZ516848A (en) * | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
CA2309705A1 (en) * | 1998-02-16 | 1999-08-19 | Dimas Tadeu Covas | Serological diagnosis of chagas' disease |
US6537749B2 (en) | 1998-04-03 | 2003-03-25 | Phylos, Inc. | Addressable protein arrays |
US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
EP0976763B1 (en) * | 1998-07-30 | 2003-11-05 | Innogenetics N.V. | Antigens and immunoassays for diagnosing Chagas' disease |
WO2000056934A1 (en) | 1999-03-24 | 2000-09-28 | Packard Bioscience Company | Continuous porous matrix arrays |
US7803765B2 (en) * | 1999-05-05 | 2010-09-28 | Phylogica Limited | Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom |
US6887470B1 (en) * | 1999-09-10 | 2005-05-03 | Conjuchem, Inc. | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
JP5064625B2 (ja) | 1999-10-27 | 2012-10-31 | バイオウルフ テクノロジーズ エルエルスィー | パターンを同定するための方法及び機械 |
US20030078192A1 (en) * | 2000-02-03 | 2003-04-24 | Winter Gregory Paul | Combinatorial protein domains |
BR0112667A (pt) | 2000-07-18 | 2006-05-09 | Correlogic Systems Inc | processo de distinção entre estados biológicos baseados em padrões ocultos de dados biológicos |
AU2002245043B2 (en) | 2000-11-16 | 2006-10-26 | Bio-Rad Laboratories, Inc. | Method for analyzing mass spectra |
CN1636068A (zh) * | 2001-02-16 | 2005-07-06 | 赛弗根生物系统股份有限公司 | 将基因表达谱与蛋白质表达谱相关联的方法 |
US7113896B2 (en) | 2001-05-11 | 2006-09-26 | Zhen Zhang | System and methods for processing biological expression data |
US7094549B2 (en) * | 2001-11-23 | 2006-08-22 | Syn X Pharma, Inc. | Fibronectin biopolymer marker indicative of insulin resistance |
US7179605B2 (en) * | 2001-11-23 | 2007-02-20 | Nanogen Inc. | Fibronectin precursor biopolymer markers indicative of alzheimer's disease |
US20020193950A1 (en) | 2002-02-25 | 2002-12-19 | Gavin Edward J. | Method for analyzing mass spectra |
CN100558909C (zh) * | 2002-08-06 | 2009-11-11 | 约翰霍普金斯大学 | 用于检测卵巢癌的生物标记的用途 |
EP1573054A4 (en) * | 2002-11-12 | 2005-12-28 | Becton Dickinson Co | DIAGNOSIS FOR SEPTICEMIA OR SIRS USING BIOMARKER PROFILES |
WO2004055198A2 (en) * | 2002-12-12 | 2004-07-01 | Chiron Corporation | Device and method for in-line blood testing using biochips |
US8346482B2 (en) * | 2003-08-22 | 2013-01-01 | Fernandez Dennis S | Integrated biosensor and simulation system for diagnosis and therapy |
US8173433B2 (en) * | 2004-08-02 | 2012-05-08 | Vermillion, Inc. | Platelet biomarkers for cancer |
-
2004
- 2004-12-06 AT AT04813321T patent/ATE525478T1/de not_active IP Right Cessation
- 2004-12-06 CA CA002547861A patent/CA2547861A1/en not_active Abandoned
- 2004-12-06 BR BRPI0417231-0A patent/BRPI0417231A/pt not_active IP Right Cessation
- 2004-12-06 WO PCT/US2004/040990 patent/WO2005055812A2/en active Application Filing
- 2004-12-06 EP EP04813321A patent/EP1718763B1/en active Active
- 2004-12-06 US US11/006,119 patent/US8043825B2/en not_active Expired - Fee Related
-
2011
- 2011-10-25 US US13/280,830 patent/US20120172356A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2005055812A3 (en) | 2005-09-15 |
EP1718763A4 (en) | 2009-02-25 |
CA2547861A1 (en) | 2005-06-23 |
EP1718763A2 (en) | 2006-11-08 |
US20050260691A1 (en) | 2005-11-24 |
US8043825B2 (en) | 2011-10-25 |
EP1718763B1 (en) | 2011-09-21 |
ATE525478T1 (de) | 2011-10-15 |
US20120172356A1 (en) | 2012-07-05 |
WO2005055812A2 (en) | 2005-06-23 |
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BRPI0417231A (pt) | método para qualificar estado da doença de chagas em um paciente, kit, produto do software, biomolécula purificada, e, métodos para qualificar estado da doença de chagas e para monitorar o curso de progressão da doença de chagas em um paciente | |
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Free format text: REFERENTE A 7A ANUIDADE. |
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