BRPI0413682A - compounds, pharmaceutical composition and methods of preparation, treatment of microbial infection and extermination of microorganism and uses - Google Patents
compounds, pharmaceutical composition and methods of preparation, treatment of microbial infection and extermination of microorganism and usesInfo
- Publication number
- BRPI0413682A BRPI0413682A BRPI0413682-9A BRPI0413682A BRPI0413682A BR PI0413682 A BRPI0413682 A BR PI0413682A BR PI0413682 A BRPI0413682 A BR PI0413682A BR PI0413682 A BRPI0413682 A BR PI0413682A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- methods
- extermination
- microorganism
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
"COMPOSTOS, COMPOSIçãO FARMACêUTICA E RESPECTIVOS MéTODOS DE PREPARAçãO DE TRATAMENTO DE INFECçãO MICROBIANA E DE EXTERMìNIO DE MICROORGANISMO E USOS". São apresentados compostos de óxido de sulfenamida da fórmula geral (I), em que A, R~ 1~, R~ 2~, X~ 1~, X~ 1~<39>, X~ 2~, X~ 2~<39>, X~ 3~, X~ 4~, X~ 4~<39>, X~ 5~ e X~ 5~<39> definem muitas variáveis e em que q é O ou 1 e p é 1 ou 2. Os compostos apresentados nos exemplos são os compostos de óxido de sulfenamida galactofuranosil e glucofuranosil, em que a variável A é o oxigenio. Também são apresentados métodos de síntese dos compostos de fórmula geral (I), composições farmacêuticas que os contenham e métodos de uso no tratamento de pacientes que estejam sofrendo de infecção microbiana."COMPOUNDS, PHARMACEUTICAL COMPOSITION AND THEIR METHODS FOR PREPARING MICROBIAN INFECTION TREATMENT AND MICROORGANISM EXTERMINATION AND USES". Sulphenamide oxide compounds of the general formula (I) are presented, wherein A, R1, R2, X1, X1, X2, X2, X2 <39>, X ~ 3 ~, X ~ 4 ~, X ~ 4 ~ <39>, X ~ 5 ~ and X ~ 5 ~ <39> define many variables and where q is O or 1 and p is 1 or 2 The compounds shown in the examples are the sulfenamide oxide compounds galactofuranosyl and glucofuranosyl, where variable A is oxygen. Also disclosed are methods of synthesizing the compounds of formula (I), pharmaceutical compositions containing them and methods of use in treating patients suffering from microbial infection.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003904501A AU2003904501A0 (en) | 2003-08-21 | Novel compounds III | |
| AU2003904500A AU2003904500A0 (en) | 2003-08-21 | Novel compounds II | |
| PCT/AU2004/001110 WO2005019236A1 (en) | 2003-08-21 | 2004-08-20 | Novel sulfenamide oxides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0413682A true BRPI0413682A (en) | 2006-10-24 |
Family
ID=34218927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0413682-9A BRPI0413682A (en) | 2003-08-21 | 2004-08-20 | compounds, pharmaceutical composition and methods of preparation, treatment of microbial infection and extermination of microorganism and uses |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1664071A1 (en) |
| JP (1) | JP2007502778A (en) |
| BR (1) | BRPI0413682A (en) |
| CA (1) | CA2535800A1 (en) |
| MX (1) | MXPA06001974A (en) |
| RU (1) | RU2006108577A (en) |
| WO (1) | WO2005019236A1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7601716B2 (en) | 2006-05-01 | 2009-10-13 | Cephalon, Inc. | Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors |
| RU2015151857A (en) | 2008-12-02 | 2019-01-15 | Уэйв Лайф Сайенсес Джапан, Инк. | METHOD FOR SYNTHESIS OF NUCLEIC ACIDS MODIFIED BY PHOSPHOR ATOMIC |
| BR112012000828A8 (en) | 2009-07-06 | 2017-10-10 | Ontorii Inc | NEW NUCLEIC ACID PRO-DRUGS AND METHODS OF THEIR USE |
| EP2620428B1 (en) | 2010-09-24 | 2019-05-22 | Wave Life Sciences Ltd. | Asymmetric auxiliary group |
| CN107365339A (en) | 2011-07-19 | 2017-11-21 | 波涛生命科学有限公司 | The method for synthesizing functionalization nucleic acid |
| BR112015000784A8 (en) | 2012-07-13 | 2018-04-03 | Wave Life Sciences Japan | ASYMMETRICAL AUXILIARY GROUP |
| WO2015107425A2 (en) | 2014-01-16 | 2015-07-23 | Wave Life Sciences Pte. Ltd. | Chiral design |
| CA3033867A1 (en) | 2016-08-17 | 2018-02-22 | Solstice Biologics, Ltd. | Polynucleotide constructs |
| US11597744B2 (en) | 2017-06-30 | 2023-03-07 | Sirius Therapeutics, Inc. | Chiral phosphoramidite auxiliaries and methods of their use |
| BR112022010924A2 (en) | 2019-12-06 | 2022-09-06 | Vertex Pharma | SUBSTITUTED TETRAHYDROFURANS AS SODIUM CHANNEL MODULATION |
| EP4171547A4 (en) | 2020-05-27 | 2024-07-17 | Axial Therapeutics Inc | Tlr2 modulator compounds, pharmaceutical compositions and uses thereof |
| CN117794920A (en) | 2021-06-04 | 2024-03-29 | 沃泰克斯药物股份有限公司 | N- (hydroxyalkyl (hetero) aryl) tetrahydrofurancarboxamides as sodium channel modulators |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1483253A4 (en) * | 2002-02-22 | 2007-03-21 | Univ Griffith | An antimicrobial agent |
-
2004
- 2004-08-20 JP JP2006523486A patent/JP2007502778A/en active Pending
- 2004-08-20 WO PCT/AU2004/001110 patent/WO2005019236A1/en not_active Application Discontinuation
- 2004-08-20 MX MXPA06001974A patent/MXPA06001974A/en not_active Application Discontinuation
- 2004-08-20 EP EP04761147A patent/EP1664071A1/en not_active Withdrawn
- 2004-08-20 CA CA002535800A patent/CA2535800A1/en not_active Abandoned
- 2004-08-20 BR BRPI0413682-9A patent/BRPI0413682A/en not_active Application Discontinuation
- 2004-08-20 RU RU2006108577/04A patent/RU2006108577A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005019236A1 (en) | 2005-03-03 |
| RU2006108577A (en) | 2007-09-27 |
| JP2007502778A (en) | 2007-02-15 |
| EP1664071A1 (en) | 2006-06-07 |
| MXPA06001974A (en) | 2006-05-31 |
| CA2535800A1 (en) | 2005-03-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |