BRPI0411057A - análogos de prostaglandina e de piperidinila - Google Patents
análogos de prostaglandina e de piperidinilaInfo
- Publication number
- BRPI0411057A BRPI0411057A BRPI0411057-9A BRPI0411057A BRPI0411057A BR PI0411057 A BRPI0411057 A BR PI0411057A BR PI0411057 A BRPI0411057 A BR PI0411057A BR PI0411057 A BRPI0411057 A BR PI0411057A
- Authority
- BR
- Brazil
- Prior art keywords
- formula
- piperidinyl
- prostaglandin
- analogs
- glaucoma
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
"ANáLOGOS DE PROSTAGLANDINA E DE PIPERIDINILA". A presente invenção fornece método de tratamento de hipertensão ocular ou glaucoma o qual compreende administrar a um animal tendo hipertensão ocular ou glaucoma quantidade terapeuticamente eficaz de um composto representado pela fórmula geral (I); na qual X, Y, Z, D e R¬ 3¬ são tais como definidos na especificação. Também são descritos compostos compreendendo a fórmula (II) ou um sal farmaceuticamente aceitável ou uma pró-droga destes; onde A, X, J, e R¬ 3¬ são tais como definidos na especificação. Também são descritos compostos tendo uma cadeia <244> e uma <sym> compreendendo a fórmula (III) ou fórmula (IV) ou derivados destes, tais como definidos na especificação ou sais ou pró-drogas farmaceuticamente aceitáveis destes.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/456,275 US6747037B1 (en) | 2003-06-06 | 2003-06-06 | Piperidinyl prostaglandin E analogs |
US10/763,702 US6977260B2 (en) | 2004-01-22 | 2004-01-22 | Piperidinyl prostaglandin E analogs |
US10/861,957 US7179820B2 (en) | 2003-06-06 | 2004-06-03 | Piperidinyl prostaglandin E analogs |
PCT/US2004/018228 WO2004108215A1 (en) | 2003-06-06 | 2004-06-04 | Piperidinyl prostaglandin e analogs |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0411057A true BRPI0411057A (pt) | 2006-07-25 |
Family
ID=33514689
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0411057-9A BRPI0411057A (pt) | 2003-06-06 | 2004-06-04 | análogos de prostaglandina e de piperidinila |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1631355B1 (pt) |
JP (1) | JP2006527189A (pt) |
AU (1) | AU2004245122A1 (pt) |
BR (1) | BRPI0411057A (pt) |
CA (1) | CA2528179C (pt) |
WO (1) | WO2004108215A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6977260B2 (en) * | 2004-01-22 | 2005-12-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
EP1761495B1 (en) * | 2004-06-04 | 2012-03-21 | Allergan, Inc. | Piperidinyl prostaglandin analogs as ocular hypotensive agents |
US20070232660A1 (en) * | 2006-04-04 | 2007-10-04 | Allergan, Inc. | Therapeutic and delivery methods of prostaglandin ep4 agonists |
US20110299830A1 (en) | 2009-03-16 | 2011-12-08 | Panasonic Corporation | Application running device |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1176261A (en) * | 1976-06-03 | 1984-10-16 | Albert G. Caldwell | Hydantoin derivatives |
GB1600127A (en) * | 1977-03-23 | 1981-10-14 | Wellcome Found | Piperazine-dione derivatives |
JPS55145669A (en) * | 1979-04-28 | 1980-11-13 | Tanabe Seiyaku Co Ltd | 8,10-diazaprostanoic acid derivative and its preparation |
GB2094743A (en) * | 1981-03-12 | 1982-09-22 | Webb John Edmund Richard | Mechanical handling apparatus |
JPS59144756A (ja) * | 1983-04-28 | 1984-08-18 | Tanabe Seiyaku Co Ltd | 8−アザプロスタン酸類化合物及びその製法 |
US4994274A (en) * | 1989-07-27 | 1991-02-19 | Allergan, Inc. | Intraocular pressure reducing 11,15-diacyl prostaglandins and method of using |
US5034413A (en) * | 1989-07-27 | 1991-07-23 | Allergan, Inc. | Intraocular pressure reducing 9,11-diacyl prostaglandins |
CA2021316C (en) * | 1989-07-27 | 2000-10-24 | Ming Fai Chan | Intraocular pressure reducing 11-acyl prostaglandins |
US5028624A (en) * | 1989-07-27 | 1991-07-02 | Allergan, Inc. | Intraocular pressure reducing 9,15-diacyl prostaglandins |
EP1409455B1 (en) * | 2001-07-16 | 2006-01-04 | F. Hoffmann-La Roche Ag | Prostaglandin analogues-as ep4 receptor agonists |
US7053085B2 (en) * | 2003-03-26 | 2006-05-30 | Merck & Co. Inc. | EP4 receptor agonist, compositions and methods thereof |
JP2006515015A (ja) * | 2003-01-10 | 2006-05-18 | エフ.ホフマン−ラ ロシュ アーゲー | プロスタグランジンアゴニストとしての2−ピペリドン誘導体 |
-
2004
- 2004-06-04 EP EP04754749.2A patent/EP1631355B1/en not_active Expired - Lifetime
- 2004-06-04 JP JP2006509090A patent/JP2006527189A/ja active Pending
- 2004-06-04 BR BRPI0411057-9A patent/BRPI0411057A/pt not_active IP Right Cessation
- 2004-06-04 CA CA2528179A patent/CA2528179C/en not_active Expired - Lifetime
- 2004-06-04 WO PCT/US2004/018228 patent/WO2004108215A1/en active Application Filing
- 2004-06-04 AU AU2004245122A patent/AU2004245122A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2006527189A (ja) | 2006-11-30 |
CA2528179C (en) | 2013-10-22 |
AU2004245122A1 (en) | 2004-12-16 |
EP1631355B1 (en) | 2014-08-13 |
CA2528179A1 (en) | 2004-12-16 |
WO2004108215A1 (en) | 2004-12-16 |
EP1631355A1 (en) | 2006-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law | ||
B07E | Notice of approval relating to section 229 industrial property law |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 12A ANUIDADE. |
|
B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |
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B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/445 (2006.01), A61P 27/06 (2006.01), C07D |