BRMU8602970U - medicamento "telmisartam + metformina" em forma combinada para doenças cardiovasculares - Google Patents
medicamento "telmisartam + metformina" em forma combinada para doenças cardiovascularesInfo
- Publication number
- BRMU8602970U BRMU8602970U BRMU8602970-3U BRMU8602970U BRMU8602970U BR MU8602970 U BRMU8602970 U BR MU8602970U BR MU8602970 U BRMU8602970 U BR MU8602970U BR MU8602970 U BRMU8602970 U BR MU8602970U
- Authority
- BR
- Brazil
- Prior art keywords
- telmisartam
- cardiovascular disease
- medicine
- insulin
- hypertension
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
O "MEDICAMENTO "TELMISARTAM + METFORMINA EM FORMA COMBINADA PARA DOENçAS CARMO VASCULARES," resuma-se a combinação de dois medicamentos utilizados contra as doenças cardiovasculares são a principal causa de morte em nosso país. Há nítida correlação entre o ganho ponderal e o excesso de peso com risco de doenças cardiovasculares. O excesso de peso predispóe a estas doenças devido anormalidades no metabolismo dos lípides, glicose e pressão arterial. A resistência à insulina 1 hiperinsulinemia parece ser um fator de risco independente de outros fatores de risco associados, como a obesidade, hiperlipidemia e hipertensão, tanto em homens como em mulheres. A insulina e os fatores de crescimento semelhantes à insulina estimulam a atividade das células musculares lisas e estão envolvidas na aterogênese e mesmo na reestenose que se segue ao reparo coronário pela angioplastia. Outros efeitos da insulina estão relacionados aos mecanismos que contribuem para o desenvolvimento tanto da hipertensão como da dislipidemia. O MEDICAMENTO "TELMISARTAM + METFORMIINA" EM FORMA COMBINADA PARA DOENCAS CARDIO VASCULARES, diminuindo a resistência insulínica, a pressão arterial, o ganho ponderal e melhorando o perfil lipídico destes paciente, reduziriam muito a probabilidade de eventos cardiovasculares e consequentemente o óbito dessa natureza em nossa população.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRMU8602970-3U BRMU8602970U (pt) | 2006-11-16 | 2006-11-16 | medicamento "telmisartam + metformina" em forma combinada para doenças cardiovasculares |
PCT/BR2007/000344 WO2008058353A2 (en) | 2006-11-16 | 2007-11-14 | Descriptive report of the patent of invention of the medicament 'telmisartana + metformin' in combined form for cardiovascular diseases |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRMU8602970-3U BRMU8602970U (pt) | 2006-11-16 | 2006-11-16 | medicamento "telmisartam + metformina" em forma combinada para doenças cardiovasculares |
Publications (1)
Publication Number | Publication Date |
---|---|
BRMU8602970U true BRMU8602970U (pt) | 2008-09-30 |
Family
ID=39402021
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRMU8602970-3U BRMU8602970U (pt) | 2006-11-16 | 2006-11-16 | medicamento "telmisartam + metformina" em forma combinada para doenças cardiovasculares |
Country Status (2)
Country | Link |
---|---|
BR (1) | BRMU8602970U (pt) |
WO (1) | WO2008058353A2 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112618526A (zh) * | 2021-01-11 | 2021-04-09 | 重庆康刻尔制药股份有限公司 | 一种治疗糖尿病合并高血压的复方制剂及其制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001272476A1 (en) * | 2000-06-16 | 2001-12-24 | Smithkline Beecham Plc | Piperidines for use as orexin receptor antagonists |
-
2006
- 2006-11-16 BR BRMU8602970-3U patent/BRMU8602970U/pt not_active IP Right Cessation
-
2007
- 2007-11-14 WO PCT/BR2007/000344 patent/WO2008058353A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2008058353A3 (en) | 2009-04-02 |
WO2008058353A2 (en) | 2008-05-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B03A | Publication of an application: publication of a patent application or of a certificate of addition of invention | ||
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE AS 4A E 5A ANUIDADES. |
|
B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2156 DE 02/05/2012. |