BR9907997A - Specific pollen promoter - Google Patents

Specific pollen promoter

Info

Publication number
BR9907997A
BR9907997A BR9907997-6A BR9907997A BR9907997A BR 9907997 A BR9907997 A BR 9907997A BR 9907997 A BR9907997 A BR 9907997A BR 9907997 A BR9907997 A BR 9907997A
Authority
BR
Brazil
Prior art keywords
promoter
pollen
nucleic acid
well
transformation
Prior art date
Application number
BR9907997-6A
Other languages
Portuguese (pt)
Inventor
Andrew James Greenland
Hilary Joan Rogers
Patrick Joseph Hussey
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9803661.9A external-priority patent/GB9803661D0/en
Priority claimed from GBGB9803660.1A external-priority patent/GB9803660D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of BR9907997A publication Critical patent/BR9907997A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8222—Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
    • C12N15/823—Reproductive tissue-specific promoters
    • C12N15/8231—Male-specific, e.g. anther, tapetum, pollen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8237—Externally regulated expression systems
    • C12N15/8238—Externally regulated expression systems chemically inducible, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
    • C12N15/8289—Male sterility

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"PROMOTOR ESPECìFICO DE PóLEN" Um ácido nucléico recombinante que compreende uma seq³ência promotora do gene ZmC5 em milho, ou uma sua variante ou fragmento, que atua como como um promotor em pólen. A seq³ência de DNA do promotor é mostrada na Figura 5. Cassetes de expressão e sistemas de expressão assim como processos de transformação, plantas transformadas incluindo a seq³ência promotora da invenção também são reivindicados. O ácido nucléico pode ser usado inter alia na produção de plantas estéreis machos e/ou híbridos assim como na transformação de pólen."PóLEN-SPECIFIC PROMOTOR" A recombinant nucleic acid comprising a promoter sequence of the ZmC5 gene in maize, or a variant or fragment thereof, which acts as a pollen promoter. The DNA sequence of the promoter is shown in Figure 5. Expression cassettes and expression systems as well as transformation processes, transformed plants including the promoter sequence of the invention are also claimed. Nucleic acid can be used inter alia in the production of sterile male and / or hybrid plants as well as in the transformation of pollen.

BR9907997-6A 1998-02-20 1999-01-22 Specific pollen promoter BR9907997A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9803661.9A GB9803661D0 (en) 1998-02-20 1998-02-20 Pollen specific promoter
GBGB9803660.1A GB9803660D0 (en) 1998-02-20 1998-02-20 Expression system
PCT/GB1999/000232 WO1999042587A1 (en) 1998-02-20 1999-01-22 Pollen specific promoter

Publications (1)

Publication Number Publication Date
BR9907997A true BR9907997A (en) 2000-10-24

Family

ID=26313163

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9907997-6A BR9907997A (en) 1998-02-20 1999-01-22 Specific pollen promoter

Country Status (11)

Country Link
EP (1) EP1054970A1 (en)
JP (1) JP2002504335A (en)
KR (1) KR20010041129A (en)
CN (1) CN1301300A (en)
AU (1) AU751438B2 (en)
BR (1) BR9907997A (en)
CA (1) CA2319079A1 (en)
DZ (1) DZ2725A1 (en)
HU (1) HUP0100787A3 (en)
IL (1) IL137971A0 (en)
WO (1) WO1999042587A1 (en)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774282B1 (en) 1999-03-08 2004-08-10 Pioneer Hi-Bred International, Inc. Maize metallothionein gene and promoter
US7288694B2 (en) 2001-07-06 2007-10-30 Monsanto Technology Llc Methods for enhancing segregation of transgenes in plants and compositions thereof
US7205454B2 (en) * 2002-07-31 2007-04-17 Bayer Bioscience N.V. Corn root preferential promoters and uses thereof
KR100537955B1 (en) * 2003-10-29 2005-12-20 학교법인고려중앙학원 A solely pollen-specific promoter
WO2005100575A2 (en) * 2004-04-14 2005-10-27 Bayer Bioscience N.V. Rice pollen-specific promoters and uses thereof
KR101951489B1 (en) 2010-01-22 2019-04-22 다우 아그로사이언시즈 엘엘씨 Excision of transgenes in genetically modified organisms
CN102010864B (en) * 2010-12-14 2012-10-17 安徽农业大学 Maize pollen tissue specific promoter and expression vector thereof
CN102533761B (en) * 2011-12-12 2013-03-20 华中科技大学 Pollen-specific promoter and expression vector and application thereof
MX344968B (en) 2012-02-01 2017-01-12 Dow Agrosciences Llc Chloroplast transit peptide.
CA3151103C (en) 2012-02-02 2024-02-13 Corteva Agriscience Llc Plant transactivation interaction motifs and uses thereof
AU2013232334A1 (en) 2012-03-13 2014-10-02 E. I. Dupont De Nemours & Company Genetic reduction of male fertility in plants
MX2014011037A (en) 2012-03-13 2015-05-15 Pioneer Hi Bred Int Genetic reduction of male fertility in plants.
WO2013138358A1 (en) * 2012-03-13 2013-09-19 Pioneer Hi-Bred International, Inc. Genetic reduction of male fertility in plants
AU2013205557B2 (en) 2012-04-17 2016-04-21 Corteva Agriscience Llc Synthetic brassica-derived chloroplast transit peptides
CN102864166B (en) * 2012-09-07 2014-04-09 江苏大学 Specific expression method of beta-D-glucuronidase gene on stigma and torus of plant
CA2884162C (en) 2012-09-07 2020-12-29 Dow Agrosciences Llc Fad3 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
UA118090C2 (en) 2012-09-07 2018-11-26 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Fad2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
JP6385644B2 (en) * 2013-03-13 2018-09-05 静岡県公立大学法人 Optical switch construct for expressing the target gene
WO2014187312A1 (en) * 2013-05-23 2014-11-27 深圳市作物分子设计育种研究院 Establishment of maintainer plant line and sterile line and use thereof
CN109593778A (en) * 2018-11-08 2019-04-09 浙江大学 A kind of plant artificial intelligence male sterile line and application
CN110093354B (en) * 2019-04-17 2020-06-05 湖南杂交水稻研究中心 Seed sorting method for fixing plant heterosis
WO2021092130A1 (en) 2019-11-05 2021-05-14 Pairwise Plants Services, Inc. Compositions and methods for rna-encoded dna-replacement of alleles
US11976278B2 (en) 2019-12-06 2024-05-07 Pairwise Plants Services, Inc. Recruitment methods and compounds, compositions and systems for recruitment
CN111139257B (en) * 2020-01-15 2022-10-14 南京农业大学 Pear PMEI protein in-vitro expression method and application thereof
US20210238598A1 (en) 2020-01-30 2021-08-05 Pairwise Plants Services, Inc. Compositions, systems, and methods for base diversification
BR112022012417A2 (en) 2020-01-31 2022-08-30 Pairwise Plants Services Inc SUPPRESSION OF SHADOW AVOIDANCE RESPONSE IN PLANTS
US20230063560A1 (en) 2020-02-04 2023-03-02 Pairwise Plans Services, Inc. Thornless and/or prickleless rubus plants
US20210261978A1 (en) 2020-02-21 2021-08-26 Pairwise Plants Services, Inc. Resistance to soybean cyst nematode through gene editing
US20210292754A1 (en) 2020-03-16 2021-09-23 Pairwise Plants Services, Inc. Natural guide architectures and methods of making and using the same
US11999946B2 (en) 2020-03-26 2024-06-04 Pairwise Plants Services, Inc. Methods for controlling meristem size for crop improvement
US11882808B2 (en) 2020-03-27 2024-01-30 Pairwise Plants Services, Inc. Methods for improving resistance to soybean rust
US20230175006A1 (en) 2020-04-06 2023-06-08 Pairwise Plants Services, Inc. Methods and compositions for increasing resistance to ear rot and stem rot disease in maize
US20230212600A1 (en) 2020-04-16 2023-07-06 Pairwise Plants Services, Inc. Methods for controlling meristem size for crop improvement
CN116096230A (en) 2020-06-02 2023-05-09 成对植物服务股份有限公司 Method for controlling meristem size to improve crops
MX2022015896A (en) 2020-06-17 2023-02-22 Pairwise Plants Services Inc Methods for controlling meristem size for crop improvement.
EP4172328A1 (en) 2020-06-30 2023-05-03 Pairwise Plants Services, Inc. Compositions, systems, and methods for base diversification
WO2022047135A1 (en) 2020-08-28 2022-03-03 Pairwise Plants Services, Inc. Engineered crispr-cas proteins and methods of use thereof
US20220145334A1 (en) 2020-11-06 2022-05-12 Pairwise Plants Services, Inc. Compositions and methods for rna-encoded dna-replacement of alleles
EP4291641A1 (en) 2021-02-11 2023-12-20 Pairwise Plants Services, Inc. Methods and compositions for modifying cytokinin oxidase levels in plants
CA3211121A1 (en) 2021-02-25 2022-09-01 Pairwise Plants Services, Inc. Methods and compositions for modifying root architecture in plants
WO2022265905A2 (en) 2021-06-14 2022-12-22 Pairwise Plants Services, Inc. Reporter constructs, compositions comprising the same, and methods of use thereof
CN117897050A (en) 2021-06-17 2024-04-16 成对植物服务股份有限公司 Modification of growth regulator family transcription factors in soybean
UY39827A (en) 2021-06-24 2023-01-31 Pairwise Plants Services Inc MODIFICATION OF UBIQUITIN LIGASE E3 HECT GENES TO IMPROVE PERFORMANCE TRAITS
WO2023278651A1 (en) 2021-07-01 2023-01-05 Pairwise Plants Services, Inc. Methods and compositions for enhancing root system development
CA3229056A1 (en) 2021-08-12 2023-02-16 Pairwise Plants Services, Inc. Modification of brassinosteroid receptor genes to improve yield traits
EP4388110A1 (en) 2021-08-17 2024-06-26 Pairwise Plants Services, Inc. Methods and compositions for modifying cytokinin receptor histidine kinase genes in plants
CA3230167A1 (en) 2021-08-30 2023-03-09 Pairwise Plants Services, Inc. Modification of ubiquitin binding peptidase genes in plants for yield trait improvement
AR126938A1 (en) 2021-09-02 2023-11-29 Pairwise Plants Services Inc METHODS AND COMPOSITIONS TO IMPROVE PLANT ARCHITECTURE AND PERFORMANCE TRAITS
US20230087522A1 (en) 2021-09-21 2023-03-23 Pairwise Plants Services, Inc. Methods and compositions for reducing pod shatter in canola
WO2023049728A1 (en) 2021-09-21 2023-03-30 Pairwise Plants Services, Inc. Color-based and/or visual methods for identifying the presence of a transgene and compositions and constructs relating to the same
US20230108968A1 (en) 2021-10-04 2023-04-06 Pairwise Plants Services, Inc. Methods for improving floret fertility and seed yield
CA3234455A1 (en) 2021-10-07 2023-04-13 Pairwise Plants Services, Inc. Methods for improving floret fertility and seed yield
AR127904A1 (en) 2021-12-09 2024-03-06 Pairwise Plants Services Inc METHODS TO IMPROVE FLOWER FERTILITY AND SEED YIELD
US20230295646A1 (en) 2021-12-13 2023-09-21 Pairwise Plants Services, Inc. Model editing systems and methods relating to the same
WO2023133440A1 (en) 2022-01-06 2023-07-13 Pairwise Plants Services, Inc. Methods and compositions for trichome removal
AR128372A1 (en) 2022-01-31 2024-04-24 Pairwise Plants Services Inc SUPPRESSION OF THE SHADE AVOIDANCE RESPONSE IN PLANTS
WO2023164722A1 (en) 2022-02-28 2023-08-31 Pairwise Plants Services, Inc. Engineered crispr-cas effector proteins and methods of use thereof
WO2023168217A1 (en) 2022-03-02 2023-09-07 Pairwise Plants Services, Inc. Modification of brassinosteroid receptor genes to improve yield traits
WO2023192838A1 (en) 2022-03-31 2023-10-05 Pairwise Plants Services, Inc. Early flowering rosaceae plants with improved characteristics
US20230357789A1 (en) 2022-04-07 2023-11-09 Pairwise Plants Services, Inc. Methods and compositions for improving resistance to fusarium head blight
WO2023205714A1 (en) 2022-04-21 2023-10-26 Pairwise Plants Services, Inc. Methods and compositions for improving yield traits
WO2023215704A1 (en) 2022-05-02 2023-11-09 Pairwise Plants Services, Inc. Methods and compositions for enhancing yield and disease resistance
WO2023215809A1 (en) 2022-05-05 2023-11-09 Pairwise Plants Services, Inc. Methods and compositions for modifying root architecture and/or improving plant yield traits
WO2024006679A1 (en) 2022-06-27 2024-01-04 Pairwise Plants Services, Inc. Methods and compositions for modifying shade avoidance in plants
US20240000031A1 (en) 2022-06-29 2024-01-04 Pairwise Plants Services, Inc. Methods and compositions for controlling meristem size for crop improvement
US20240002873A1 (en) 2022-06-29 2024-01-04 Pairwise Plants Services, Inc. Methods and compositions for controlling meristem size for crop improvement
US20240043857A1 (en) 2022-08-04 2024-02-08 Pairwise Plants Services, Inc. Methods and compositions for improving yield traits
US20240060081A1 (en) 2022-08-11 2024-02-22 Pairwise Plants Services, Inc. Methods and compositions for controlling meristem size for crop improvement
WO2024054880A1 (en) 2022-09-08 2024-03-14 Pairwise Plants Services, Inc. Methods and compositions for improving yield characteristics in plants
WO2024130102A2 (en) 2022-12-16 2024-06-20 Pairwise Plants Services, Inc. Fusion proteins comprising an intein polypeptide and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901677D0 (en) * 1989-01-26 1989-03-15 Ici Plc Hybrid seed production
ES2250961T3 (en) * 1992-06-12 2006-04-16 Bayer Bioscience N.V. MAINTENANCE OF PLANTS WITH MALE STERILITY.
GB9515161D0 (en) * 1995-07-24 1995-09-20 Zeneca Ltd Production of male sterile plants
JPH11514233A (en) * 1995-10-13 1999-12-07 パーデュー・リサーチ・ファウンデーション Hybrid plant production method
GB9607517D0 (en) * 1996-04-11 1996-06-12 Gene Shears Pty Ltd The use of DNA Sequences
WO1999008830A1 (en) * 1997-08-18 1999-02-25 Zakrytoe Aktsionernoe Obschestvo 'firma Novye Sistemnye Tekhnologii' Method of laser welding of thin sheet metallic components

Also Published As

Publication number Publication date
WO1999042587A1 (en) 1999-08-26
CN1301300A (en) 2001-06-27
EP1054970A1 (en) 2000-11-29
AU751438B2 (en) 2002-08-15
HUP0100787A2 (en) 2002-04-29
AU2287699A (en) 1999-09-06
DZ2725A1 (en) 2003-09-01
IL137971A0 (en) 2001-10-31
JP2002504335A (en) 2002-02-12
CA2319079A1 (en) 1999-08-26
HUP0100787A3 (en) 2003-04-28
KR20010041129A (en) 2001-05-15

Similar Documents

Publication Publication Date Title
BR9907997A (en) Specific pollen promoter
BR0011499A (en) Nucleic acid molecules from plants and transgenic wheat plant cells and their use for the production of modified starch
ATE352638T1 (en) REVERSE TWO-HYBRID SYSTEMS
BR0010989A (en) Genetically modified plants and plant cells with increased activity of an amylosaccharide protein and a branching enzyme
BR9814276A (en) Surface antigens
BR9910311A (en) Nucleic acid molecules encoding wheat enzymes, which participate in the synthesis of starch
FI881185A (en) HUMAN MANGAN-SUPEROXIDE DISMUTAS (HMN-SOD).
BR9815588A (en) Genes that encode enzymes for lignin biosynthesis and their uses
BR9714513A (en) Genes that code for amino acid-deacetylases with specificity for n-acetyl-l-phosphinothricin, their isolation and use
DE69840387D1 (en) NIK PROTEIN, NUCLEIC ACID AND METHOD
DK0624641T3 (en) Thermostable nucleic acid polymerase
BR9810870A (en) Regulation of quinolate phosphoribosyl transferase expression
DK1115874T3 (en) Alzheimer's disease secretase
NO973685L (en) Multi-tumor aberrant growth genes
DE69802389T2 (en) CONNECTIONS USED AS EFFECTORS OF NEUROEXCITATORY AMINO ACID SENSITIVE RECEPTORS OF THE CENTRAL VENEER SYSTEM, THEIR PRODUCTION AND THEIR BIOLOGICAL USE
BR9909745A (en) Peptide, fusion peptide, medication, composition, nucleic acid fragment, chimeric gene, cloning or expression vector for the transformation of a host organism, transformed host organisms, transformed plant cell, transformed plant and its seed, transformation process of host organisms, transformed plant culture process and heliomycide preparation process
ATE209684T1 (en) DNA SEQUENCES FOR MATRIX METAL PROTEASES, THEIR PREPARATION AND USE
FI970579A0 (en) An andenovirus comprising a gene encoding glutathione peroxidase
ES2124470T3 (en) RECOMBINANT LISTINE OF MISTLETOE.
ATE264913T1 (en) PROTEASE-RESISTANT ANALOGUES OF THROMBOMODULIN
BR9006855A (en) URATE OXIDASE ACTIVITY PROTEIN, RECOMBINANT GENE THAT CODES IT, EXPRESSION VECTOR, MICROORGANISMS AND TRANSFORMED CELLS
DE69132889T2 (en) SUPERIOR THROMBOMODULIN ANALOGS FOR PHARMACEUTICAL USE
BR9813805A (en) "nucleotide polymorphisms in soy"
BR9811853A (en) Processes to increase yield in plants
DE60213406D1 (en) PHARMACOLOGICAL APPLICATIONS OF MITOCHONDRIAL DNA ASSAYS

Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved
B25G Requested change of headquarter approved
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1990 DE 25/02/2009.