BR9906561A - Monoclonal antibody, hybridoma cell, plasmid pbluebachis2a-dm a recombinant, recombinant baculovirus, and process for probing dendritic cells in a sample - Google Patents
Monoclonal antibody, hybridoma cell, plasmid pbluebachis2a-dm a recombinant, recombinant baculovirus, and process for probing dendritic cells in a sampleInfo
- Publication number
- BR9906561A BR9906561A BR9906561-4A BR9906561A BR9906561A BR 9906561 A BR9906561 A BR 9906561A BR 9906561 A BR9906561 A BR 9906561A BR 9906561 A BR9906561 A BR 9906561A
- Authority
- BR
- Brazil
- Prior art keywords
- monoclonal antibody
- recombinant
- dendritic cells
- sample
- hybridoma cell
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 210000004443 dendritic cell Anatomy 0.000 title abstract 2
- 210000004408 hybridoma Anatomy 0.000 title abstract 2
- 241000701447 unidentified baculovirus Species 0.000 title abstract 2
- 239000013612 plasmid Substances 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 2
- 210000005259 peripheral blood Anatomy 0.000 abstract 1
- 239000011886 peripheral blood Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Abstract
"ANTICORPO MONOCLONAL, CéLULA DE HIBRIDOMA, PLASMìDEO pBlueBacHis2A-DM <244> RECOMBINANTE, BACULOVìRUS RECOMBINANTE, E, PROCESSO PARA SONDAGEM DE CéLULAS DENDRìTICAS DE UMA AMOSTRA". Descreve-se o anticorpo monoclonal, 3-6-A, que se liga à região extracelular de um DM <244> e à célula de hibridroma, KHB-DM, com um n° de_depósito de KCTC-0485BP, que produz o anticorpo monoclonal 3-6-A. O anticorpo monoclonal mostra capacidade de ligação potente e especificidade exclusiva em células dendríticas, entre os leucóticos do sangue periférico."MONOCLONAL ANTIBODY, HYBRIDOMA CELL, PLASMIDY pBlueBacHis2A-DM <244> RECOMBINANT, RECOMBINANT BACULOVIRUS, AND PROCESS FOR PROCEDURE FOR DENDRITIC CELLS OF A SAMPLE". We describe the monoclonal antibody, 3-6-A, which binds to the extracellular region of a DM <244> and the hybrroma cell, KHB-DM, with a deposit number of KCTC-0485BP, which produces the monoclonal antibody 3-6-A. The monoclonal antibody shows potent binding capacity and unique specificity in dendritic cells, among peripheral blood leukotics.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019980024502A KR100295558B1 (en) | 1998-06-27 | 1998-06-27 | Among the primary immune cells, the monoclonal antibody 3-6-A (dendritic cell), which specifically acts on the surface of dendritic cells |
PCT/KR1999/000212 WO2000000592A1 (en) | 1998-06-27 | 1999-04-29 | Monoclonal antibody 3-6-a specific to surface of dendritic cells among the peripheral blood leukocytes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9906561A true BR9906561A (en) | 2000-08-15 |
Family
ID=19541044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9906561-4A BR9906561A (en) | 1998-06-27 | 1999-04-29 | Monoclonal antibody, hybridoma cell, plasmid pbluebachis2a-dm a recombinant, recombinant baculovirus, and process for probing dendritic cells in a sample |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1012243A1 (en) |
JP (1) | JP2002519021A (en) |
KR (1) | KR100295558B1 (en) |
CN (1) | CN1275161A (en) |
AU (1) | AU3444499A (en) |
BR (1) | BR9906561A (en) |
CA (1) | CA2301024A1 (en) |
WO (1) | WO2000000592A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7560534B2 (en) | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
IL152652A0 (en) | 2000-05-08 | 2003-06-24 | Medarex Inc | Human monoclonal antibodies to dendritic cells |
US9259459B2 (en) | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
EP1594533B1 (en) | 2003-01-31 | 2012-04-11 | Celldex Research Corporation | Antibody vaccine conjugates and uses therefor |
CN101888856B (en) | 2007-11-07 | 2014-08-27 | 塞尔德克斯医疗公司 | Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9117522D0 (en) * | 1991-08-14 | 1991-10-02 | Medical Res Council | Ligands for dendritic cells, their uses and production |
IL107483A0 (en) * | 1993-11-03 | 1994-02-27 | Yeda Res & Dev | Bone marrow transplantation |
WO1995015340A1 (en) * | 1993-12-03 | 1995-06-08 | The Board Of Trustees Of Leland Stanford Junior University | Monoclonal antibodies to antigens expressed by human dendritic cells |
CA2257827A1 (en) * | 1996-06-17 | 1997-12-24 | Genetics Institute, Inc. | Polynucleotide encoding secreted protein isolated from human dendritic cells |
-
1998
- 1998-06-27 KR KR1019980024502A patent/KR100295558B1/en not_active IP Right Cessation
-
1999
- 1999-04-29 JP JP2000557345A patent/JP2002519021A/en active Pending
- 1999-04-29 CN CN99801328A patent/CN1275161A/en active Pending
- 1999-04-29 WO PCT/KR1999/000212 patent/WO2000000592A1/en not_active Application Discontinuation
- 1999-04-29 AU AU34444/99A patent/AU3444499A/en not_active Abandoned
- 1999-04-29 CA CA002301024A patent/CA2301024A1/en not_active Abandoned
- 1999-04-29 EP EP99916067A patent/EP1012243A1/en not_active Withdrawn
- 1999-04-29 BR BR9906561-4A patent/BR9906561A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR20000003285A (en) | 2000-01-15 |
AU3444499A (en) | 2000-01-17 |
WO2000000592A1 (en) | 2000-01-06 |
CA2301024A1 (en) | 2000-01-06 |
KR100295558B1 (en) | 2001-07-12 |
JP2002519021A (en) | 2002-07-02 |
EP1012243A1 (en) | 2000-06-28 |
CN1275161A (en) | 2000-11-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 3A,4A,5A,6A,7A E 8A ANUIDADES |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO NAO CUMPRIMENTO DO DESPACHO 8.6 NA RPI 1910 DE 14/08/2007. |