BR9815035A - Useful method and compositions for the activation of inactive transgenes. - Google Patents

Useful method and compositions for the activation of inactive transgenes.

Info

Publication number
BR9815035A
BR9815035A BR9815035-9A BR9815035A BR9815035A BR 9815035 A BR9815035 A BR 9815035A BR 9815035 A BR9815035 A BR 9815035A BR 9815035 A BR9815035 A BR 9815035A
Authority
BR
Brazil
Prior art keywords
compositions
activation
useful method
inactive
binding domain
Prior art date
Application number
BR9815035-9A
Other languages
Portuguese (pt)
Inventor
Eric Russel Ward
Charles David Guyer
Sandra Lynn Volrath
Joern Goerlach
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR9815035A publication Critical patent/BR9815035A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8217—Gene switch
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Patente de Invenção: <B>"MéTODO E COMPOSIçõES úTEIS PARA A ATIVAçãO DE TRANSGENES INATIVOS"<D>. Esta invenção refere-se a composições e método para induzir expressão de uma seq³ência de DNA desejada em uma planta transformada estável que expressa um fator de transcrição híbrido, compreendendo uma fusão do domínio de ligação de DNA e de um domínio de ativação de transcrição, que é um efetuador de expressão das seq³ências de DNA desejadas, controladas por um promotor sintético, compreendendo o promotor sintético preferencialmente cópias concateméricas do sítio de atuação cis reconhecido por domínio de ligação de DNA do fator de transcrição híbrido, fundido com um promotor.Invention Patent: <B> "USEFUL METHOD AND COMPOSITIONS FOR ACTIVATION OF INACTIVE TRANSGENS" <D>. This invention relates to compositions and method for inducing expression of a desired DNA sequence in a stable transformed plant that expresses a hybrid transcription factor, comprising a fusion of the DNA binding domain and a transcription activation domain, which it is an expression effector of the desired DNA sequences, controlled by a synthetic promoter, the synthetic promoter preferably comprising concatemeric copies of the cis-acting site recognized by the DNA binding domain of the hybrid transcription factor, fused with a promoter.

BR9815035-9A 1997-11-26 1998-11-24 Useful method and compositions for the activation of inactive transgenes. BR9815035A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97883097A 1997-11-26 1997-11-26
PCT/EP1998/007577 WO1999027119A1 (en) 1997-11-26 1998-11-24 Method and compositions useful for the activation of silent transgenes

Publications (1)

Publication Number Publication Date
BR9815035A true BR9815035A (en) 2000-10-03

Family

ID=25526430

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9815035-9A BR9815035A (en) 1997-11-26 1998-11-24 Useful method and compositions for the activation of inactive transgenes.

Country Status (9)

Country Link
EP (1) EP1034284A1 (en)
JP (1) JP2001524315A (en)
CN (1) CN1280623A (en)
AR (1) AR016696A1 (en)
AU (1) AU745867B2 (en)
BR (1) BR9815035A (en)
CA (1) CA2311632A1 (en)
WO (1) WO1999027119A1 (en)
ZA (1) ZA9810771B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7705500A (en) * 1999-09-20 2001-04-24 Center For The Application Of Molecular Biology To International Agriculture Methods for site-associated modification of gene activity and nucleic acid structure
CN1390261A (en) * 1999-10-01 2003-01-08 巴斯福股份公司 GMP synthetase derived from plants
WO2001031025A2 (en) * 1999-10-25 2001-05-03 Basf Aktiengesellschaft Formylglycinamidinribotide synthase from plants
US6376746B1 (en) 1999-12-13 2002-04-23 Paradigm Genetics, Inc. Modified minimal promoters
US6331663B1 (en) 1999-12-13 2001-12-18 Paradigm Genetics, Inc. Modified full length promoters
GB0017547D0 (en) * 2000-07-17 2000-09-06 Bp Chem Int Ltd Supported polymerisation catalysts
GB0125784D0 (en) * 2001-10-26 2001-12-19 Syngenta Ltd Novel expression system
US20060075522A1 (en) 2004-07-31 2006-04-06 Jaclyn Cleveland Genes and uses for plant improvement
EP1788861B1 (en) 2004-08-24 2017-04-12 Monsanto Technology, LLC Adenylate translocator protein gene non-coding regulatory elements for use in plants
CA2864444A1 (en) * 2012-02-15 2013-08-22 Mice With Horns, Llc Transgenic animals with customizable traits

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0375407B1 (en) * 1988-12-21 1995-06-14 Canon Kabushiki Kaisha Recovery mechanism of an ink jet recording apparatus
CA2047633A1 (en) * 1990-09-12 1992-03-13 Ben Bowen Inactivation of gene transcription in plants using altered transcriptional activators
US5409823A (en) * 1992-09-24 1995-04-25 Ciba-Geigy Corporation Methods for the production of hybrid seed
US5688939A (en) * 1994-12-22 1997-11-18 Novartis Finance Corporation Plant adenylosuccinate synthetase and DNA coding therefor
GB9502456D0 (en) * 1995-02-08 1995-03-29 Univ Warwick Control of genes in transgenic plants
GB9603069D0 (en) * 1996-02-14 1996-04-10 Medical Res Council Improvements in or relating to gene expression
EP0823480A1 (en) * 1996-08-06 1998-02-11 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Controlled gene expression in plants
US5968793A (en) * 1997-06-24 1999-10-19 E. I. Du Pont De Nemours And Company Specific gene activation by chimeric Gal4 transcription factors in stable transgenic plants

Also Published As

Publication number Publication date
AR016696A1 (en) 2001-07-25
AU745867B2 (en) 2002-04-11
CN1280623A (en) 2001-01-17
JP2001524315A (en) 2001-12-04
WO1999027119A1 (en) 1999-06-03
EP1034284A1 (en) 2000-09-13
CA2311632A1 (en) 1999-06-03
ZA9810771B (en) 1999-05-26
AU1963999A (en) 1999-06-15

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law