BR9814282A - "compositions and methods for treating attention deficit disorder and attention deficit / hyperactivity disorder with methylphenidate" - Google Patents
"compositions and methods for treating attention deficit disorder and attention deficit / hyperactivity disorder with methylphenidate"Info
- Publication number
- BR9814282A BR9814282A BR9814282-8A BR9814282A BR9814282A BR 9814282 A BR9814282 A BR 9814282A BR 9814282 A BR9814282 A BR 9814282A BR 9814282 A BR9814282 A BR 9814282A
- Authority
- BR
- Brazil
- Prior art keywords
- attention deficit
- disorder
- methylphenidate
- compositions
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Patente de Invenção: <B>"COMPOSIçõES E MéTODOS PARA TRATAMENTO DE DISTúRBIO DE DéFICIT DE ATENçãO E DISTúRBIO DE DéFICIT/HIPERATIVIDADE DE ATENçãO COM METILFENIDATO"<D>. A invenção refere-se a um método de tratamento de Distúrbio de Déficit de Atenção (ADD) e Distúrbio de Déficit de Atenção/Hiperatividade (ADHD) e a composições para aplicação tópica de metilfenidato compreendendo metilfenidato em um sistema finito flexível, em que o metilfenidato está presente em uma proporção suficiente para atingir substancialmente uma cinética de ordem zero para transferência para a pele ou mucosa de um paciente carente dele por um período de pelo menos 10 horas.Invention Patent: <B> "COMPOSITIONS AND METHODS FOR TREATING ATTENTION DEFICIT DISORDER AND ATTENTION DEFICIT / HYPERACTIVITY DISORDER WITH METHYLENIDATE" <D>. The invention relates to a method of treating Attention Deficit Disorder (ADD) and Attention Deficit / Hyperactivity Disorder (ADHD) and compositions for topical application of methylphenidate comprising methylphenidate in a flexible finite system, in which the methylphenidate it is present in a proportion sufficient to achieve substantially zero order kinetics for transfer to the skin or mucosa of a patient in need of it for a period of at least 10 hours.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6951097P | 1997-12-15 | 1997-12-15 | |
US09/163,351 US6210705B1 (en) | 1997-12-15 | 1998-09-30 | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
PCT/US1998/026560 WO1999030694A2 (en) | 1997-12-15 | 1998-12-14 | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9814282A true BR9814282A (en) | 2000-10-03 |
Family
ID=26750154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9814282-8A BR9814282A (en) | 1997-12-15 | 1998-12-14 | "compositions and methods for treating attention deficit disorder and attention deficit / hyperactivity disorder with methylphenidate" |
Country Status (28)
Country | Link |
---|---|
US (2) | US6210705B1 (en) |
EP (2) | EP1037615B1 (en) |
JP (3) | JP4316800B2 (en) |
KR (1) | KR100633348B1 (en) |
CN (1) | CN1368876A (en) |
AR (1) | AR014062A1 (en) |
AT (1) | ATE260652T1 (en) |
AU (1) | AU752027B2 (en) |
BR (1) | BR9814282A (en) |
CA (1) | CA2315237C (en) |
CZ (2) | CZ300535B6 (en) |
DE (1) | DE69822199T2 (en) |
DK (1) | DK1037615T3 (en) |
ES (2) | ES2219926T3 (en) |
HK (2) | HK1049447A1 (en) |
HU (1) | HU226615B1 (en) |
IL (1) | IL136760A0 (en) |
LV (1) | LV12558B (en) |
NO (1) | NO329974B1 (en) |
NZ (1) | NZ505689A (en) |
PE (1) | PE20000120A1 (en) |
PL (1) | PL195315B1 (en) |
PT (1) | PT1037615E (en) |
RU (1) | RU2233156C2 (en) |
SI (1) | SI20360B (en) |
TR (1) | TR200001736T2 (en) |
TW (2) | TWI244396B (en) |
WO (1) | WO1999030694A2 (en) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
US20020102291A1 (en) * | 1997-12-15 | 2002-08-01 | Noven Pharmaceuticals, Inc. | Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
GB9913458D0 (en) * | 1999-06-09 | 1999-08-11 | Medeva Europ Ltd | The therapeutic use of d-threo-methylphenidate |
GB9918735D0 (en) * | 1999-08-09 | 1999-10-13 | Straken Limited | Transdermal patches |
CO5261532A1 (en) * | 1999-11-15 | 2003-03-31 | Novartis Ag | SILILATED HETEROCICLIC COMPOUNDS, PROCEDURE FOR THE PREPARATION OF THESE AND PHARMACEUTICAL COMPOSITION CONTAINING THEM |
ATE252903T1 (en) * | 1999-12-17 | 2003-11-15 | Celltech Pharma Europ Ltd | MEDICINAL PRODUCTS FOR THE TREATMENT OF CONVULSIVE CONDITIONS |
US6455066B1 (en) | 2000-03-10 | 2002-09-24 | Epicept Corporation | Intradermal-penetration agents for topical local anesthetic administration |
US6905016B2 (en) * | 2000-03-14 | 2005-06-14 | Noven Pharmaceuticals, Inc. | Packaging system for transdermal drug delivery systems |
US7674480B2 (en) * | 2000-06-23 | 2010-03-09 | Teva Pharmaceutical Industries Ltd. | Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition |
US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
DE10060550C1 (en) * | 2000-12-06 | 2002-04-18 | Lohmann Therapie Syst Lts | Transdermal therapeutic system for administration of oxybutynin, especially for treatment of bladder dysfunction, having two-phase matrix layer of active agent-containing droplets dispersed in adhesive |
CN1250206C (en) * | 2001-03-07 | 2006-04-12 | 久光制药株式会社 | Adhesive patch |
FR2822049B1 (en) * | 2001-03-13 | 2003-08-01 | Dbv Medica 1 | PATCH INTENDED IN PARTICULAR TO DETECT THE STATE OF SENSITIZATION OF A SUBJECT TO AN ALLERGEN, METHOD OF MANUFACTURING AND USE |
WO2002074286A1 (en) * | 2001-03-16 | 2002-09-26 | Alza Corporation | Transdermal patch for administering fentanyl |
US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
DE10141650C1 (en) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Safe transdermal therapeutic system for administration of fentanyl or analogous analgesics, having matrix layer of carboxy group-free polyacrylate adhesive providing high permeation rate |
DE10141652B4 (en) * | 2001-08-24 | 2011-04-07 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system based on polyacrylate pressure-sensitive adhesives without functional groups and its use |
US20030049272A1 (en) * | 2001-08-30 | 2003-03-13 | Yatindra Joshi | Pharmaceutical composition which produces irritation |
JP4354678B2 (en) * | 2002-08-28 | 2009-10-28 | 久光製薬株式会社 | Patch |
US6913768B2 (en) | 2002-09-24 | 2005-07-05 | Shire Laboratories, Inc. | Sustained release delivery of amphetamine salts |
AU2003299659A1 (en) | 2002-12-13 | 2004-07-09 | Durect Corporation | Oral drug delivery system comprising high viscosity liquid carrier materials |
UA84303C2 (en) * | 2003-10-28 | 2008-10-10 | Новен Фармасьютикалз, Инк. | Transdermal drug delivery system |
WO2006078887A2 (en) | 2005-01-20 | 2006-07-27 | Institute For Molecular Medicine, Inc. | Methylphenidate derivatives and uses of them |
WO2006078984A2 (en) * | 2005-01-20 | 2006-07-27 | Institute For Molecular Medicine, Inc. | Uses of methylphenidate derivatives |
US9393218B2 (en) * | 2005-12-23 | 2016-07-19 | Epinamics Gmbh | Use of film-forming hair care polymers from the group of polyurethanes and pharmaceutical preparations and patches that contain these polymers |
US8715723B2 (en) * | 2006-02-27 | 2014-05-06 | Noven Pharmaceuticals, Inc. | Compositions and methods for delivery of amino-functional drugs |
MY144201A (en) * | 2006-05-01 | 2011-08-15 | Colgate Palmolive Co | Oral care composition with silicone composite |
US20100104621A1 (en) * | 2007-02-21 | 2010-04-29 | Connected Health Systems, Llc | Treating adhd and other diseases involving inflammation |
RU2499583C2 (en) * | 2007-10-15 | 2013-11-27 | Алза Корпорейшн | Replaced transdermal of administration of phentanyl |
FR2924350B1 (en) * | 2007-12-03 | 2010-08-13 | Dbv Tech | METHOD AND COMPOSITIONS FOR SKIN VACCINATION |
FR2924349B1 (en) * | 2007-12-03 | 2010-01-01 | Dbv Tech | ALLERGEN DISENSIBILITY METHOD |
JP2011506318A (en) | 2007-12-06 | 2011-03-03 | デュレクト コーポレーション | Oral pharmaceutical formulation |
CN102006893A (en) * | 2007-12-31 | 2011-04-06 | 阿克拉伦特公司 | Mucosal tissue dressing and method of use |
FR2926466B1 (en) * | 2008-01-23 | 2010-11-12 | Dbv Tech | METHOD FOR MANUFACTURING PATCHES BY ELECTROSPRAY |
US8217047B2 (en) * | 2008-05-27 | 2012-07-10 | Dmi Acquisition Corp. | Therapeutic methods and compounds |
US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
JP5155128B2 (en) * | 2008-12-11 | 2013-02-27 | 日東電工株式会社 | Methylphenidate patch preparation |
US9228779B2 (en) * | 2009-06-05 | 2016-01-05 | Megtec Systems, Inc. | Infrared float bar |
EP2364695A1 (en) | 2010-02-10 | 2011-09-14 | Nitto Denko Corporation | Methylphenidate patch preparation |
US20110200663A1 (en) * | 2010-02-12 | 2011-08-18 | Nitto Denko Corporation | Methylphenidate patch preparation |
US9119809B2 (en) | 2011-03-23 | 2015-09-01 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US10905652B2 (en) | 2011-03-23 | 2021-02-02 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US9603809B2 (en) | 2011-03-23 | 2017-03-28 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
US9283214B2 (en) | 2011-03-23 | 2016-03-15 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US11241391B2 (en) | 2011-03-23 | 2022-02-08 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US9498447B2 (en) | 2011-03-23 | 2016-11-22 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US8927010B2 (en) | 2011-03-23 | 2015-01-06 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
WO2012129551A1 (en) | 2011-03-23 | 2012-09-27 | Ironshore Pharmaceuticals & Development, Inc. | Methods and compositions for treatment of attention deficit disorder |
US10292937B2 (en) | 2011-03-23 | 2019-05-21 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
US8916588B2 (en) | 2011-03-23 | 2014-12-23 | Ironshore Pharmaceuticals & Development, Inc. | Methods for treatment of attention deficit hyperactivity disorder |
KR101616111B1 (en) | 2011-07-28 | 2016-04-27 | 켐팜 인코포레이티드 | Methylphenidate-prodrugs, processes of making and using the same |
AR092999A1 (en) | 2012-10-15 | 2015-05-13 | Noven Pharma | COMPOSITIONS AND METHODS FOR THE TRANSDERMIC ADMINISTRATION OF METHYLPHENIDATE |
US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
WO2014106014A1 (en) | 2012-12-28 | 2014-07-03 | Noven Pharmaceuticals, Inc | Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol |
JP6359032B2 (en) | 2012-12-28 | 2018-07-18 | ノーヴェン ファーマシューティカルズ インコーポレイテッド | Multi-polymer composition for transdermal drug delivery |
US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
US11337936B2 (en) | 2013-03-14 | 2022-05-24 | Noven Pharmaceuticals, Inc. | Amphetamine transdermal compositions with acrylic block copolymer |
AR095259A1 (en) | 2013-03-15 | 2015-09-30 | Noven Pharma | COMPOSITIONS AND METHODS FOR THE TRANSDERMAL ADMINISTRATION OF TERTIARY AMINE DRUGS |
CA2905131A1 (en) | 2013-03-15 | 2014-09-18 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
AR095260A1 (en) | 2013-03-15 | 2015-09-30 | Noven Pharma | COMPOSITIONS OF STABLE TRANSDERMAL AMPHETAMINS AND MANUFACTURING METHODS |
SI3087984T1 (en) | 2013-12-25 | 2021-08-31 | Fujimoto Co., Ltd. | Prophylactic and therapeutic agent for attention-deficit/hyperactivity disorder |
US9980921B2 (en) * | 2016-06-30 | 2018-05-29 | Taho Pharmaceuticals Ltd. | Transdermal delivery system containing methylphenidate or its salts and methods thereof |
CN106511264A (en) * | 2016-11-15 | 2017-03-22 | 北京万全德众医药生物技术有限公司 | Methylphenidate hydrochloride oral solution and preparation method thereof |
NZ754751A (en) | 2016-12-11 | 2022-05-27 | Kempharm Inc | Compositions comprising methylphenidate-prodrugs, processes of making and using the same |
EP3598982A1 (en) | 2018-07-23 | 2020-01-29 | Centre National De La Recherche Scientifique | Bioconjugates of neuropeptides derivatives |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2957880A (en) | 1953-12-23 | 1960-10-25 | Ciba Pharm Prod Inc | Process for the conversion of stereoisomers |
US4310509A (en) | 1979-07-31 | 1982-01-12 | Minnesota Mining And Manufacturing Company | Pressure-sensitive adhesive having a broad spectrum antimicrobial therein |
US4655767A (en) | 1984-10-29 | 1987-04-07 | Dow Corning Corporation | Transdermal drug delivery devices with amine-resistant silicone adhesives |
US5474783A (en) | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
US5656286A (en) | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
JP2693212B2 (en) * | 1989-03-28 | 1997-12-24 | 日東電工株式会社 | Tape preparation for disease treatment |
AU1992592A (en) * | 1991-05-24 | 1993-01-08 | Pharmavene, Inc. | Treatment of drug withdrawal symptoms and drug craving with type b monoamine oxidase inhibitors |
US5629019A (en) | 1992-02-27 | 1997-05-13 | Alza Corporation | Formulations with hydrophobic permeation enhancers |
AU4673993A (en) | 1992-07-28 | 1994-02-14 | Procter & Gamble Company, The | Pharmaceutical composition for topical use containing a crosslinked cationic polymer and an alkoxylated ether |
CH691209A5 (en) | 1993-09-06 | 2001-05-15 | Scherrer Inst Paul | Manufacturing process for a polymer electrolyte and electrochemical cell with this polymer electrolyte. |
EP0689920B1 (en) | 1994-06-29 | 1999-10-13 | Hennecke GmbH | Method and apparatus for the continuous production of foam plastic blocks or sheets |
US5601839A (en) | 1995-04-26 | 1997-02-11 | Theratech, Inc. | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
US5780050A (en) | 1995-07-20 | 1998-07-14 | Theratech, Inc. | Drug delivery compositions for improved stability of steroids |
WO1998039042A1 (en) | 1997-03-07 | 1998-09-11 | Jackson Richard R | Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods |
GB9711032D0 (en) | 1997-05-30 | 1997-07-23 | Johnson Matthey Plc | Compound as a stimulant for the central nervous system |
US6684641B2 (en) | 1999-12-15 | 2004-02-03 | Osaka Gas Co., Ltd. | Fluid distributor, burner device, gas turbine engine, and cogeneration system |
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1998
- 1998-09-30 US US09/163,351 patent/US6210705B1/en not_active Expired - Lifetime
- 1998-12-14 ES ES98963170T patent/ES2219926T3/en not_active Expired - Lifetime
- 1998-12-14 ES ES10011358.8T patent/ES2452517T3/en not_active Expired - Lifetime
- 1998-12-14 WO PCT/US1998/026560 patent/WO1999030694A2/en active Application Filing
- 1998-12-14 CZ CZ20002209A patent/CZ300535B6/en not_active IP Right Cessation
- 1998-12-14 DE DE69822199T patent/DE69822199T2/en not_active Expired - Lifetime
- 1998-12-14 TR TR2000/01736T patent/TR200001736T2/en unknown
- 1998-12-14 SI SI9820083A patent/SI20360B/en not_active IP Right Cessation
- 1998-12-14 IL IL13676098A patent/IL136760A0/en not_active IP Right Cessation
- 1998-12-14 JP JP2000538677A patent/JP4316800B2/en not_active Expired - Lifetime
- 1998-12-14 BR BR9814282-8A patent/BR9814282A/en not_active Application Discontinuation
- 1998-12-14 DK DK98963170T patent/DK1037615T3/en active
- 1998-12-14 HU HU0004539A patent/HU226615B1/en not_active IP Right Cessation
- 1998-12-14 PT PT98963170T patent/PT1037615E/en unknown
- 1998-12-14 KR KR1020007006477A patent/KR100633348B1/en not_active IP Right Cessation
- 1998-12-14 EP EP98963170A patent/EP1037615B1/en not_active Expired - Lifetime
- 1998-12-14 CN CN98813634A patent/CN1368876A/en active Pending
- 1998-12-14 PL PL98341596A patent/PL195315B1/en unknown
- 1998-12-14 NZ NZ505689A patent/NZ505689A/en not_active IP Right Cessation
- 1998-12-14 TW TW092128573A patent/TWI244396B/en not_active IP Right Cessation
- 1998-12-14 CZ CZ2009-132A patent/CZ2009132A3/en not_active IP Right Cessation
- 1998-12-14 AU AU18249/99A patent/AU752027B2/en not_active Ceased
- 1998-12-14 EP EP10011358.8A patent/EP2314288B1/en not_active Expired - Lifetime
- 1998-12-14 TW TW087120741A patent/TWI242452B/en not_active IP Right Cessation
- 1998-12-14 AT AT98963170T patent/ATE260652T1/en active
- 1998-12-14 CA CA002315237A patent/CA2315237C/en not_active Expired - Lifetime
- 1998-12-14 RU RU2000119097/15A patent/RU2233156C2/en not_active IP Right Cessation
- 1998-12-15 AR ARP980106392A patent/AR014062A1/en not_active Application Discontinuation
- 1998-12-15 PE PE1998001219A patent/PE20000120A1/en not_active Application Discontinuation
-
2000
- 2000-06-15 NO NO20003096A patent/NO329974B1/en not_active IP Right Cessation
- 2000-07-17 LV LVP-00-92A patent/LV12558B/en unknown
- 2000-07-18 US US09/618,626 patent/US6348211B1/en not_active Expired - Lifetime
-
2003
- 2003-03-05 HK HK03101632.9A patent/HK1049447A1/en unknown
-
2008
- 2008-11-13 JP JP2008291364A patent/JP2009073856A/en active Pending
-
2011
- 2011-10-20 HK HK11111285.8A patent/HK1156872A1/en not_active IP Right Cessation
-
2012
- 2012-12-26 JP JP2012282405A patent/JP2013056944A/en active Pending
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