BR9807980A - Use of a compound and compound to treat a mammal with cognitive impairment - Google Patents

Use of a compound and compound to treat a mammal with cognitive impairment

Info

Publication number
BR9807980A
BR9807980A BR9807980-8A BR9807980A BR9807980A BR 9807980 A BR9807980 A BR 9807980A BR 9807980 A BR9807980 A BR 9807980A BR 9807980 A BR9807980 A BR 9807980A
Authority
BR
Brazil
Prior art keywords
compound
mammal
breflato
treat
cognitive impairment
Prior art date
Application number
BR9807980-8A
Other languages
Portuguese (pt)
Inventor
Richard L Gabriel
Original Assignee
Allelix Pharm Eco L P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allelix Pharm Eco L P filed Critical Allelix Pharm Eco L P
Publication of BR9807980A publication Critical patent/BR9807980A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"USO DE UM COMPOSTO E COMPOSTO PARA TRATAR DE MAMìFERO COM DISFUNçãO COGNITIVA". Descritos estão métodos para tratar um mamífero sofrendo de disfunção cognitiva. O método compreende administrar uma quantidade terapeuticamente efetiva de Breflato ou de um derivado de Breflato, como descrito aqui. Também descritos estão métodos para melhorar funções cognitivas em um mamífero. O método compreende administrar uma quantidade intensificadora cognitiva efetiva de Breflato ou de um derivado de Breflato, como descrito aqui."USE OF A COMPOUND AND COMPOUND TO TREAT MAMMALIAN WITH COGNITIVE DYSFUNCTION". Described are methods for treating a mammal suffering from cognitive impairment. The method comprises administering a therapeutically effective amount of Breflato or a Breflato derivative, as described herein. Also described are methods for improving cognitive functions in a mammal. The method comprises administering an effective cognitive enhancing amount of Breflato or a Breflato derivative, as described here.

BR9807980-8A 1997-02-05 1998-02-04 Use of a compound and compound to treat a mammal with cognitive impairment BR9807980A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3688997P 1997-02-05 1997-02-05
PCT/US1998/002009 WO1998033498A1 (en) 1997-02-05 1998-02-04 Drugs for memory enhancement

Publications (1)

Publication Number Publication Date
BR9807980A true BR9807980A (en) 2000-03-28

Family

ID=21891226

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9807980-8A BR9807980A (en) 1997-02-05 1998-02-04 Use of a compound and compound to treat a mammal with cognitive impairment

Country Status (6)

Country Link
EP (1) EP0969830A1 (en)
JP (1) JP2001512422A (en)
AU (1) AU6141798A (en)
BR (1) BR9807980A (en)
CA (1) CA2279947A1 (en)
WO (1) WO1998033498A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1868480A (en) * 2001-08-31 2006-11-29 科塞普特治疗公司 Methods for inhibiting cognitive deterioration in adults with down's syndrome
CN102316865B (en) 2008-12-12 2017-04-19 科耐特有限公司 L-lysine for improving normal cognitive functions
CN112851622B (en) * 2019-11-28 2023-01-10 中国海洋大学 Macrolide brefeldin A ester derivative and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242932A (en) * 1991-12-17 1993-09-07 The Rockefeller University Treatment of amyloidosis associated with alzheimer disease
US5696154A (en) * 1994-06-29 1997-12-09 The United States Of America As Represented By The Department Of Health And Human Services Brefeldin A derivatives and their utility in the treatment of cancer
KR970706271A (en) * 1994-09-20 1997-11-03 스티븐슨 린다 에스. DRUGS TO IMPROVE SYNAPTIC TRANSMISSION
US5618837A (en) * 1995-06-07 1997-04-08 Zymogenetics, Inc. PDGF antagonists III

Also Published As

Publication number Publication date
AU6141798A (en) 1998-08-25
CA2279947A1 (en) 1998-08-06
JP2001512422A (en) 2001-08-21
EP0969830A1 (en) 2000-01-12
WO1998033498A1 (en) 1998-08-06

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired