BR9806303A - Thermoformed drug delivery system and dosage unit - Google Patents

Thermoformed drug delivery system and dosage unit

Info

Publication number
BR9806303A
BR9806303A BR9806303-0A BR9806303A BR9806303A BR 9806303 A BR9806303 A BR 9806303A BR 9806303 A BR9806303 A BR 9806303A BR 9806303 A BR9806303 A BR 9806303A
Authority
BR
Brazil
Prior art keywords
delivery system
thermoformed
drug delivery
dosage unit
drug
Prior art date
Application number
BR9806303-0A
Other languages
Portuguese (pt)
Inventor
Steven E Frisbee
Deirdre M Barrow
Joseph Cascone
Barry D Mccarthy
Bernard M Kiernan
Hanan S Anwar
Beuford A Bogue
Claude Bayard
Abhijit Barnerjee
Original Assignee
Fuisz Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/946,070 external-priority patent/US6013280A/en
Application filed by Fuisz Technologies Ltd filed Critical Fuisz Technologies Ltd
Publication of BR9806303A publication Critical patent/BR9806303A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"SISTEMA DE DISTRIBUIçãO DE DROGA TERMOFORMADO, E, UNIDADE DE DOSAGEM". Um sistema de distribuição de droga processado via técnicas de transformação, apresentando propriedades de rápida liberação de agente ativo que são úteis nas formas de dosagem farmacêuticas. O sistema de distribuição pode ser utilizado como partículas que contêm agentes ativos e agentes de solubilização e que estão contidos em uma forma de dosagem."THERMOFORMED DRUG DISTRIBUTION SYSTEM, AND DOSING UNIT". A drug delivery system processed via transformation techniques, featuring quick release properties of active agent that are useful in pharmaceutical dosage forms. The delivery system can be used as particles that contain active agents and solubilizing agents and that are contained in a dosage form.

BR9806303-0A 1997-10-07 1998-09-28 Thermoformed drug delivery system and dosage unit BR9806303A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/946,070 US6013280A (en) 1997-10-07 1997-10-07 Immediate release dosage forms containing microspheres
US12916498A 1998-08-05 1998-08-05
PCT/US1998/020266 WO1999017744A1 (en) 1997-10-07 1998-09-28 Immediate release drug delivery forms

Publications (1)

Publication Number Publication Date
BR9806303A true BR9806303A (en) 2000-03-14

Family

ID=26827301

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9806303-0A BR9806303A (en) 1997-10-07 1998-09-28 Thermoformed drug delivery system and dosage unit

Country Status (7)

Country Link
EP (1) EP0966269A1 (en)
JP (1) JP2000507991A (en)
KR (1) KR20000069356A (en)
AU (1) AU9587198A (en)
BR (1) BR9806303A (en)
CA (1) CA2273272C (en)
WO (1) WO1999017744A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0580860T4 (en) * 1991-04-16 2005-03-21 Nippon Shinyaku Co Ltd Process for preparing a solid dispersion
CA2348452A1 (en) * 1998-10-27 2000-05-04 Biovail Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
IE981008A1 (en) * 1998-12-02 2000-06-14 Fuisz Internat Ltd Microparticles Containing Water Insoluble Active Agents
AU784340B2 (en) 1999-12-23 2006-03-16 Pfizer Products Inc. Pharmaceutical compositions providing enhanced drug concentrations
US8980870B2 (en) * 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations
US9149433B2 (en) * 2004-11-30 2015-10-06 Basf Corporation Method for formation of micro-prilled polymers
EP1897543A1 (en) 2006-08-30 2008-03-12 Euro-Celtique S.A. Buprenorphine- wafer for drug substitution therapy
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1388786A (en) * 1972-04-03 1975-03-26 Scherer Corp R P Integral solid gel-lattice dosage form of high-moisture content
DE3927113C2 (en) * 1989-08-17 1993-11-25 Dolorgiet Gmbh & Co Kg Agent for the treatment of severe pain conditions and process for their preparation
CA2095776C (en) * 1992-05-12 2007-07-10 Richard C. Fuisz Rapidly dispersable compositions containing polydextrose
ATE150297T1 (en) * 1992-06-10 1997-04-15 Nanosystems Llc SURFACE MODIFIED NSAID NANOPARTICLES
US5683720A (en) * 1994-10-28 1997-11-04 Fuisz Technologies Ltd. Liquiflash particles and method of making same
IE80467B1 (en) * 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs
JPH11514979A (en) * 1995-09-07 1999-12-21 フイズ テクノロジーズ リミテッド Bioavailable system for virtually insoluble bioactive agents

Also Published As

Publication number Publication date
AU9587198A (en) 1999-04-27
JP2000507991A (en) 2000-06-27
CA2273272A1 (en) 1999-04-15
KR20000069356A (en) 2000-11-25
EP0966269A1 (en) 1999-12-29
WO1999017744A1 (en) 1999-04-15
CA2273272C (en) 2004-09-21

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired