BR9805320A - Derivatives of n- (4-carbamimidoylphenylamino) phenyl-glycinamide. - Google Patents

Derivatives of n- (4-carbamimidoylphenylamino) phenyl-glycinamide.

Info

Publication number
BR9805320A
BR9805320A BR9805320-5A BR9805320A BR9805320A BR 9805320 A BR9805320 A BR 9805320A BR 9805320 A BR9805320 A BR 9805320A BR 9805320 A BR9805320 A BR 9805320A
Authority
BR
Brazil
Prior art keywords
carbamimidoylphenylamino
glycinamide
phenyl
derivatives
denivatives
Prior art date
Application number
BR9805320-5A
Other languages
Portuguese (pt)
Inventor
Katrin Groebke
Yu-Hua Ji
Sabine Wallbaum
Lutz Weber
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR9805320A publication Critical patent/BR9805320A/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"DERIVADOS DE N-(4-CARBAMIMIDOILFENILAMINO) FENIL-GLICINAMIDA"<D>. Os novos derivados de N-(4-carbamimidoilfenilamino) fenilglicinamida da fórmula onde E, G^ 1^, G^ 2^, Q, R, e X^ 1^ a X^ 4^ são cada um como definidos na descrição, e seus hidratos, solvatos e sais fisiologicamente aceitáveis podem ser usados como inibidores da formação dos fatores de coagulação Xa, Ixa e trombina induzidos pelo fator VIIa e pelo fator de tecido, especificamente como medicamentos para o tratamento e/ou prevenção de trombose, apoplexia, infarto cardíaco, inflamação e ateriosclerose ou como agentes antitumor.Invention Patent: <B> "N- (4-CARBAMIMIDOYLPHENYLAMINE) DENIVATIVES" PHENYL-GLYCINAMIDE "<D>. The new N- (4-carbamimidoylphenylamino) phenylglycinamide derivatives of the formula where E, G ^ 1 ^, G ^ 2 ^, Q, R, and X ^ 1 ^ to X ^ 4 ^ are each as defined in the description, and its physiologically acceptable hydrates, solvates and salts can be used as inhibitors of the formation of coagulation factors Xa, Ixa and thrombin induced by factor VIIa and tissue factor, specifically as medicines for the treatment and / or prevention of thrombosis, stroke, infarction inflammation and atheriosclerosis or as anti-tumor agents.

BR9805320-5A 1997-12-04 1998-12-04 Derivatives of n- (4-carbamimidoylphenylamino) phenyl-glycinamide. BR9805320A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97121285 1997-12-04

Publications (1)

Publication Number Publication Date
BR9805320A true BR9805320A (en) 2000-04-11

Family

ID=8227734

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9805320-5A BR9805320A (en) 1997-12-04 1998-12-04 Derivatives of n- (4-carbamimidoylphenylamino) phenyl-glycinamide.

Country Status (10)

Country Link
AR (1) AR013783A1 (en)
BR (1) BR9805320A (en)
CO (1) CO5011108A1 (en)
HR (1) HRP980614B1 (en)
ID (1) ID21408A (en)
PE (1) PE20000060A1 (en)
PL (1) PL193297B1 (en)
TR (1) TR199802513A3 (en)
YU (1) YU55798A (en)
ZA (1) ZA9811077B (en)

Also Published As

Publication number Publication date
AR013783A1 (en) 2001-01-10
TR199802513A2 (en) 1999-06-21
ID21408A (en) 1999-06-10
ZA9811077B (en) 1999-06-04
YU55798A (en) 2001-07-10
PE20000060A1 (en) 2000-02-07
HRP980614B1 (en) 2003-02-28
PL330104A1 (en) 1999-06-07
PL193297B1 (en) 2007-01-31
CO5011108A1 (en) 2001-02-28
HRP980614A2 (en) 1999-08-31
TR199802513A3 (en) 1999-06-21

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Legal Events

Date Code Title Description
B03H Publication of an application: rectification [chapter 3.8 patent gazette]

Free format text: REFERENTE A RPI 1527 DE 11/04/2000, QUANTO AO ITEM (72)

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements