BR9804858A - M-todo de prepara-Æo de antibiÄtico b-lactam - Google Patents

M-todo de prepara-Æo de antibiÄtico b-lactam

Info

Publication number
BR9804858A
BR9804858A BR9804858A BR9804858A BR9804858A BR 9804858 A BR9804858 A BR 9804858A BR 9804858 A BR9804858 A BR 9804858A BR 9804858 A BR9804858 A BR 9804858A BR 9804858 A BR9804858 A BR 9804858A
Authority
BR
Brazil
Prior art keywords
lactam antibiotic
antibiotic preparation
preparation
lactam
antibiotic
Prior art date
Application number
BR9804858A
Other languages
English (en)
Inventor
Thomas Van Der Does
Erix De Vroom
Jagdish Chabder Kapur
Original Assignee
Gist Brocades Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Bv filed Critical Gist Brocades Bv
Publication of BR9804858A publication Critical patent/BR9804858A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/04—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/06—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by desacylation of the substituent in the 6 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR9804858A 1997-04-22 1998-04-22 M-todo de prepara-Æo de antibiÄtico b-lactam BR9804858A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97201198 1997-04-22
PCT/EP1998/002458 WO1998048038A1 (en) 1997-04-22 1998-04-22 A METHOD FOR PREPARING A β-LACTAM ANTIBIOTIC

Publications (1)

Publication Number Publication Date
BR9804858A true BR9804858A (pt) 1999-08-24

Family

ID=8228238

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9804858A BR9804858A (pt) 1997-04-22 1998-04-22 M-todo de prepara-Æo de antibiÄtico b-lactam

Country Status (10)

Country Link
US (1) US20020006642A1 (pt)
EP (1) EP0918879A1 (pt)
JP (1) JP2000512860A (pt)
KR (1) KR20000022106A (pt)
CN (1) CN1224471A (pt)
AU (1) AU7529198A (pt)
BR (1) BR9804858A (pt)
PL (1) PL330725A1 (pt)
WO (1) WO1998048038A1 (pt)
ZA (1) ZA983387B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1186668A1 (en) * 2000-09-08 2002-03-13 Dsm N.V. An enzymatic process for preparing Beta-lactam compounds
JP2010520752A (ja) * 2007-03-09 2010-06-17 ディーエスエム アイピー アセッツ ビー．ブイ． ベータ−ラクタム化合物の調製方法
ATE525475T1 (de) * 2007-07-27 2011-10-15 Fermenta Biotech Ltd Verfahren zur herstellung von penicillin- oder cephalosporin-antibiotika
CN103865911B (zh) * 2014-02-20 2015-10-21 浙江普洛得邦制药有限公司 青霉素g酰化酶突变体及其在合成头孢类抗生素中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3528965A (en) * 1968-02-09 1970-09-15 Beecham Group Ltd Penicillin ester process and products
CH640240A5 (en) * 1979-02-09 1983-12-30 I B S A Inst Biochimique Sa Preparation of penicillins and cephalosporins from precursors obtained by hydrolysis of natural penicillins/cephalosporins, using enzymatic complexes immobilised on solid carriers
EP0339751B1 (en) * 1988-04-26 1996-05-29 Gist-Brocades N.V. Process for the enzymatic preparation of beta-lactams
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
ATE234846T1 (de) * 1995-12-08 2003-04-15 Dsm Nv Verfahren zur herstellung eines anitibiotkums
WO1998002551A2 (en) * 1996-07-16 1998-01-22 Gist-Brocades B.V. Process for the production of adipoyl cephalosporins

Also Published As

Publication number Publication date
AU7529198A (en) 1998-11-13
WO1998048038A1 (en) 1998-10-29
US20020006642A1 (en) 2002-01-17
JP2000512860A (ja) 2000-10-03
EP0918879A1 (en) 1999-06-02
KR20000022106A (ko) 2000-04-25
PL330725A1 (en) 1999-05-24
ZA983387B (en) 1999-01-26
CN1224471A (zh) 1999-07-28

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Legal Events

Date Code Title Description
TC Change of name
HHT Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: republication

Free format text: ALTERADO DE: GIST-BROCADES B.V. - REFERENCIA RPI 1552 DE 03/10/2000 - COD. 25.4 - ITEM DESPACHO.

PC Transfer

Free format text: DSM N.V. (NL)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A, 7A, 8A, 9A, 10A E 11A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2021 DE 29/09/2009.