BR9714904B1 - vacina antìgena homóloga e microorganismo transgênico para a mesma. - Google Patents
vacina antìgena homóloga e microorganismo transgênico para a mesma.Info
- Publication number
- BR9714904B1 BR9714904B1 BRPI9714904-7A BR9714904A BR9714904B1 BR 9714904 B1 BR9714904 B1 BR 9714904B1 BR 9714904 A BR9714904 A BR 9714904A BR 9714904 B1 BR9714904 B1 BR 9714904B1
- Authority
- BR
- Brazil
- Prior art keywords
- vaccine
- organism
- pathogenic micro
- transgenic microorganism
- homologous
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 244000005700 microbiome Species 0.000 title 1
- 230000009261 transgenic effect Effects 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 244000000010 microbial pathogen Species 0.000 abstract 3
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
- 230000002238 attenuated effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/23—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Brucella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1997/023032 WO1999029340A1 (en) | 1997-12-05 | 1997-12-05 | An over-expressing homologous antigen vaccine and a method of making the same |
| CNB971825173A CN1321693C (zh) | 1997-12-05 | 1997-12-05 | 一种过量表达的同源抗原疫苗及其制备方法 |
| OA1200000163A OA11421A (en) | 1997-12-05 | 2000-06-05 | An over-expressing homologous antigen vaccine and a method of making the same. |
| US09/692,623 US6811787B1 (en) | 1997-12-05 | 2000-10-20 | Over-expressing homologous antigen vaccine and a method of making the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR9714904A BR9714904A (pt) | 2001-11-27 |
| BR9714904B1 true BR9714904B1 (pt) | 2010-07-13 |
Family
ID=39591168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9714904-7A BR9714904B1 (pt) | 1997-12-05 | 1997-12-05 | vacina antìgena homóloga e microorganismo transgênico para a mesma. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6149920A (pt) |
| EP (1) | EP1035863B1 (pt) |
| CN (1) | CN1321693C (pt) |
| AT (1) | ATE320264T1 (pt) |
| AU (1) | AU759776C (pt) |
| BR (1) | BR9714904B1 (pt) |
| CA (1) | CA2317806A1 (pt) |
| ES (1) | ES2259449T3 (pt) |
| NZ (1) | NZ504993A (pt) |
| OA (1) | OA11421A (pt) |
| PT (1) | PT1035863E (pt) |
| WO (1) | WO1999029340A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9714904B1 (pt) * | 1997-12-05 | 2010-07-13 | vacina antìgena homóloga e microorganismo transgênico para a mesma. | |
| US20030068324A1 (en) * | 2001-04-06 | 2003-04-10 | Jean-Michel Fournier | Conjugate vaccine composed of the polysaccharide moiety of the lipopolysaccharide of Vibrio cholerae O139 bound to tetanus toxoid |
| WO2004054508A2 (en) * | 2002-12-12 | 2004-07-01 | Walter Reed Army Institute Of Research Department Of The Army | Immunogenic compositions including rough phenotype brucella host strains and complementation dna fragments |
| US7364745B2 (en) * | 2004-02-06 | 2008-04-29 | Virginia Tech Intellectual Properties, Inc. | Development of a live, attenuated, recombinant vaccine for Brucellosis |
| US20050249755A1 (en) * | 2004-03-03 | 2005-11-10 | Mikeljon Nikolich | Mutant strains of Brucella melitensis and immunogenic compositions |
| WO2007050099A2 (en) * | 2004-12-01 | 2007-05-03 | Aeras Global Tb Vaccine Foundation | Recombinant bcg strains with attenuated immunosuppresive properties |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4888170A (en) * | 1981-10-22 | 1989-12-19 | Research Corporation | Vaccines obtained from antigenic gene products of recombinant genes |
| US5468485A (en) * | 1987-06-04 | 1995-11-21 | Washington University | Avirulent microbes and uses therefor |
| US6043057A (en) | 1988-09-16 | 2000-03-28 | Vitec Aktiebolag | Recombinant systems for expression of the cholera B-sub-unit with the aid of foreign promoters and/or leader peptides |
| EP0692031B1 (en) | 1993-02-22 | 2007-04-11 | The General Hospital Corporation | Heterologous antigens in live cell vaccine strains |
| DK0686195T3 (da) * | 1993-02-26 | 2006-11-27 | Novozymes As | Fremgangsmåde og system til forhöjet produktion af kommercielt vigtige exoproteiner i grampositive bakterier |
| EP1221488A1 (en) | 1993-06-04 | 2002-07-10 | Whitehead Institute For Biomedical Research | Stress proteins and uses therefor |
| AU7410798A (en) | 1996-11-29 | 1998-06-22 | General Hospital Corporation, The | Heterologous antigens in live cell V |
| AU6969798A (en) * | 1997-04-15 | 1998-11-11 | Baylor College Of Medicine | (pasteurella haemolytica) vaccine |
| BR9714904B1 (pt) * | 1997-12-05 | 2010-07-13 | vacina antìgena homóloga e microorganismo transgênico para a mesma. |
-
1997
- 1997-12-05 BR BRPI9714904-7A patent/BR9714904B1/pt not_active IP Right Cessation
- 1997-12-05 AT AT97953216T patent/ATE320264T1/de not_active IP Right Cessation
- 1997-12-05 US US09/091,521 patent/US6149920A/en not_active Expired - Lifetime
- 1997-12-05 CN CNB971825173A patent/CN1321693C/zh not_active Expired - Lifetime
- 1997-12-05 ES ES97953216T patent/ES2259449T3/es not_active Expired - Lifetime
- 1997-12-05 AU AU57013/98A patent/AU759776C/en not_active Ceased
- 1997-12-05 CA CA002317806A patent/CA2317806A1/en not_active Abandoned
- 1997-12-05 WO PCT/US1997/023032 patent/WO1999029340A1/en active IP Right Grant
- 1997-12-05 PT PT97953216T patent/PT1035863E/pt unknown
- 1997-12-05 NZ NZ504993A patent/NZ504993A/xx unknown
- 1997-12-05 EP EP97953216A patent/EP1035863B1/en not_active Expired - Lifetime
-
2000
- 2000-06-05 OA OA1200000163A patent/OA11421A/en unknown
- 2000-10-20 US US09/692,623 patent/US6811787B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1035863A4 (en) | 2003-04-16 |
| US6811787B1 (en) | 2004-11-02 |
| AU5701398A (en) | 1999-06-28 |
| PT1035863E (pt) | 2006-07-31 |
| EP1035863A1 (en) | 2000-09-20 |
| EP1035863B1 (en) | 2006-03-15 |
| NZ504993A (en) | 2002-11-26 |
| AU759776B2 (en) | 2003-05-01 |
| US6149920A (en) | 2000-11-21 |
| ES2259449T3 (es) | 2006-10-01 |
| WO1999029340A1 (en) | 1999-06-17 |
| BR9714904A (pt) | 2001-11-27 |
| ATE320264T1 (de) | 2006-04-15 |
| CN1321693C (zh) | 2007-06-20 |
| CN1290173A (zh) | 2001-04-04 |
| CA2317806A1 (en) | 1999-06-17 |
| OA11421A (en) | 2004-04-21 |
| AU759776C (en) | 2004-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 13/07/2010, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time | ||
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |