BR9712838A - Proteases and their variants featuring peptide protease inhibitors fused to them - Google Patents

Proteases and their variants featuring peptide protease inhibitors fused to them

Info

Publication number
BR9712838A
BR9712838A BR9712838-4A BR9712838A BR9712838A BR 9712838 A BR9712838 A BR 9712838A BR 9712838 A BR9712838 A BR 9712838A BR 9712838 A BR9712838 A BR 9712838A
Authority
BR
Brazil
Prior art keywords
proteases
protease inhibitors
peptide protease
relates
present
Prior art date
Application number
BR9712838-4A
Other languages
Portuguese (pt)
Inventor
Charles Winston Saunders
John Mcmillan Mciver
James Michael Armpriester
Robert Scott Youngquist
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of BR9712838A publication Critical patent/BR9712838A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)

Abstract

Patente de Invenção:<B>"PROTEìNA DE FUSãO COMPATìVEL COM DETERGENTE, VARIANTE DE INIBIDOR DE PROTEASE, COMPOSIçãO DE LIMPEZA E DETERGENTE, PROCESSO DE PREPARAçãO DE PROTEìNA DE FUSãO, ADN, VETOR, SISTEMA DE EXPRESSãO, GENE E KIT DE TESTE"<D>. A presente invenção refere-se a proteínas de fusão e a seus usos. A presente invenção também se refere aos genes codificam tais proteínas de fusão. A presente invenção também se refere a composições compreendendo tais proteínas de fusão para limpeza.Invention Patent: <B> "DETERGENT COMPATIBLE FUSION PROTEIN, PROTEASE INHIBITOR VARIANT, CLEANING AND DETERGENT COMPOSITION, PROCESS OF PREPARATION OF FUSION PROTEIN, DNA, VECTOR, EXPRESSION SYSTEM, GENE AND TEXT SYSTEM, GENE" D>. The present invention relates to fusion proteins and their uses. The present invention also relates to the genes encoding such fusion proteins. The present invention also relates to compositions comprising such fusion proteins for cleaning.

BR9712838-4A 1996-09-24 1997-09-23 Proteases and their variants featuring peptide protease inhibitors fused to them BR9712838A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2694796P 1996-09-24 1996-09-24
PCT/US1997/016354 WO1998013483A1 (en) 1996-09-24 1997-09-23 Proteases and their variants having peptide protease inhibitors fused to them

Publications (1)

Publication Number Publication Date
BR9712838A true BR9712838A (en) 2000-12-05

Family

ID=21834730

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9712838-4A BR9712838A (en) 1996-09-24 1997-09-23 Proteases and their variants featuring peptide protease inhibitors fused to them

Country Status (7)

Country Link
EP (1) EP0941312A1 (en)
JP (1) JP2000506393A (en)
CN (1) CN1238805A (en)
AR (1) AR009818A1 (en)
BR (1) BR9712838A (en)
CA (1) CA2266418A1 (en)
WO (1) WO1998013483A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1317052A (en) * 1998-07-07 2001-10-10 宝洁公司 Proteases fused with variants of streptomyces subtilisin proteases inhibitor
WO2002016619A1 (en) * 2000-08-21 2002-02-28 Novozymes A/S Method for production of a protease-inhibitor complex
US6783941B2 (en) 2000-12-06 2004-08-31 Novozymes A/S Method for producing a polynucleotide library in vitro by mismatch repair of heteroduplexes
CN1612723A (en) * 2001-11-13 2005-05-04 宝洁公司 Local compositions containing enzymes stabilized with inhibitors
RU2546834C2 (en) * 2009-09-25 2015-04-10 Новозимс А/С Detergent composition
JP2012180514A (en) * 2011-02-10 2012-09-20 Sanyo Chem Ind Ltd Liquid detergent composition
JP6214382B2 (en) * 2013-12-19 2017-10-18 花王株式会社 Cleaning composition for clothing
US20210380667A1 (en) 2018-10-10 2021-12-09 Novozymes A/S Chymotrypsin Inhibitor Variants And The Use Thereof
WO2020088393A1 (en) * 2018-10-31 2020-05-07 青岛蔚蓝生物集团有限公司 Method for producing washing enzyme having protease resistance

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340740C (en) * 1987-12-08 1999-09-14 Eileen R. Mulvihill Co-expression in eukaryotic cells
US5371198A (en) * 1991-12-16 1994-12-06 Novo Nordisk A/S Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
DK43192D0 (en) * 1992-03-31 1992-03-31 Novo Nordisk As detergent composition

Also Published As

Publication number Publication date
JP2000506393A (en) 2000-05-30
WO1998013483A1 (en) 1998-04-02
CN1238805A (en) 1999-12-15
CA2266418A1 (en) 1998-04-02
AR009818A1 (en) 2000-05-03
EP0941312A1 (en) 1999-09-15

Similar Documents

Publication Publication Date Title
YU8997A (en) Purified protein having serinic proteaze inhibiting activity and pharmaceutical preparation containing them
KR100380006B1 (en) Protease variants and compositions
JP4028592B2 (en) High alkaline serine protease
ES2061929T5 (en) NEW PROTEOLYTIC ENZYMES AND THEIR USE IN DETERGENTS.
WO2002088340A3 (en) Alkaline protease variants and detergents and cleaning agents containing said alkaline protease variants
DK1456368T3 (en) New alkaline protease from Bacillus sp. (DSM 14392) and detergent containing this new alkaline protease
DE69101557D1 (en) ENZYMATIC DETERGENT COMPOSITION AND METHOD FOR STABILIZING THE ENZYME.
DK1337648T3 (en) New cyclodextrin glucanotransferase (CGTase) from Bacillus agaradherens (DSM 9948) and detergents with this new cyclodextrin glucanotransferase
KR20010093174A (en) Subtilase enzymes of the i-s1 and i-s2 sub-groups having an additional amino acid residue in an active site loop region
HUP0500058A2 (en) Novel alkaline protease variants and detergents and cleansers containing these novel alkaline protease variants
BR9712838A (en) Proteases and their variants featuring peptide protease inhibitors fused to them
DE69226636D1 (en) STABILIZED ENZYMS
HUP9801638A2 (en) Proteinase k variants having decreased adsorption and increased hydrolysis
WO2000001831A3 (en) Proteases fused with variants of streptomyces subtilisin inhibitor
KR20010093169A (en) Subtilase enzymes of the i-s1 and i-s2 sub-groups having an additional amino acid residue in the active site loop region
EP0842267A4 (en) Mch2, AN APOPTOTIC CYSTEINE PROTEASE, AND COMPOSITIONS FOR MAKING AND METHODS OF USING THE SAME
HUP9800767A2 (en) Subtilisin dy variants having decreased adsorption and increased hydrolysis
WO1999003984A3 (en) Proteases from gram-positive organisms
JP2000506394A (en) Stabilized proteinaceous protease inhibitors and variants thereof
CO4480058A1 (en) CODING GENES AND EXPRESSION PROCEDURE OF A NEW ENZYME: FTALIL AMIDASA
KR20010093164A (en) Subtilase enzymes of the i-s1 and i-s2 sub-groups having an additional amino acid residue in an active site loop region
BR9912519A (en) Stabilized variants of streptomyces subtilisin inhibitor
MX9503070A (en) Clover yellow vein virus protease gene.
PE20000177A1 (en) THERMOSENSITIVE dtsR GEN
FR2792651A1 (en) New nucleotide sequences isolated from Pyrococcus abyssi encode proteins useful in industry

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]