BR9710018A - Preparation of (7S, trans) -2- (2-pyrimidinyl) -7- (hydroxymethyl) octahydro-2H-pyrido [1,2-A] pyrazine - Google Patents

Preparation of (7S, trans) -2- (2-pyrimidinyl) -7- (hydroxymethyl) octahydro-2H-pyrido [1,2-A] pyrazine

Info

Publication number
BR9710018A
BR9710018A BR9710018A BR9710018A BR9710018A BR 9710018 A BR9710018 A BR 9710018A BR 9710018 A BR9710018 A BR 9710018A BR 9710018 A BR9710018 A BR 9710018A BR 9710018 A BR9710018 A BR 9710018A
Authority
BR
Brazil
Prior art keywords
octahydro
pyrido
pyrazine
pyrimidinyl
hydroxymethyl
Prior art date
Application number
BR9710018A
Other languages
Portuguese (pt)
Inventor
Sally Gut Ruggeri
Philip Dietrich Hammen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR9710018A publication Critical patent/BR9710018A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BR9710018A 1996-07-01 1997-06-16 Preparation of (7S, trans) -2- (2-pyrimidinyl) -7- (hydroxymethyl) octahydro-2H-pyrido [1,2-A] pyrazine BR9710018A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2051196P 1996-07-01 1996-07-01
PCT/IB1997/000704 WO1998000425A1 (en) 1996-07-01 1997-06-16 Preparation of (7s,trans)-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2h-pyrido[1,2-a]pyrazine

Publications (1)

Publication Number Publication Date
BR9710018A true BR9710018A (en) 1999-08-10

Family

ID=21799016

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9710018A BR9710018A (en) 1996-07-01 1997-06-16 Preparation of (7S, trans) -2- (2-pyrimidinyl) -7- (hydroxymethyl) octahydro-2H-pyrido [1,2-A] pyrazine

Country Status (16)

Country Link
EP (1) EP0912569A1 (en)
JP (1) JPH11512751A (en)
KR (1) KR20000022490A (en)
CN (1) CN1221418A (en)
AR (1) AR008251A1 (en)
AU (1) AU2974497A (en)
BR (1) BR9710018A (en)
CA (1) CA2259496A1 (en)
CZ (1) CZ434998A3 (en)
ID (1) ID19779A (en)
IL (1) IL127037A0 (en)
PL (1) PL330962A1 (en)
TR (1) TR199802743T2 (en)
WO (1) WO1998000425A1 (en)
YU (1) YU61098A (en)
ZA (1) ZA975806B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX19222A (en) * 1989-01-23 1993-12-01 Pfizer ANSIOLYTIC AGENTS BIS-AZA-BICYCLIC
EP0569387B1 (en) * 1991-01-31 1995-04-05 Pfizer Inc. Resolution of trans-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2h-pyrido 1,2-a]pyrazine

Also Published As

Publication number Publication date
ID19779A (en) 1998-07-30
CA2259496A1 (en) 1998-01-08
YU61098A (en) 1999-09-27
IL127037A0 (en) 1999-09-22
TR199802743T2 (en) 1999-03-22
WO1998000425A1 (en) 1998-01-08
CZ434998A3 (en) 1999-11-17
PL330962A1 (en) 1999-06-21
EP0912569A1 (en) 1999-05-06
AU2974497A (en) 1998-01-21
JPH11512751A (en) 1999-11-02
CN1221418A (en) 1999-06-30
ZA975806B (en) 1998-12-30
KR20000022490A (en) 2000-04-25
AR008251A1 (en) 1999-12-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A , 6A , 7A E 8A ANUIDADES.