BR9708559A - Denaturants for sympathomimetic amine salts - Google Patents
Denaturants for sympathomimetic amine saltsInfo
- Publication number
- BR9708559A BR9708559A BR9708559A BR9708559A BR9708559A BR 9708559 A BR9708559 A BR 9708559A BR 9708559 A BR9708559 A BR 9708559A BR 9708559 A BR9708559 A BR 9708559A BR 9708559 A BR9708559 A BR 9708559A
- Authority
- BR
- Brazil
- Prior art keywords
- denaturants
- amine salts
- sympathomimetic amine
- sympathomimetic
- salts
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1523996P | 1996-04-10 | 1996-04-10 | |
| US3260296P | 1996-12-11 | 1996-12-11 | |
| US4055097P | 1997-03-13 | 1997-03-13 | |
| PCT/US1997/005509 WO1997037689A2 (en) | 1996-04-10 | 1997-04-01 | Denaturants for sympathomimetic amine salts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9708559A true BR9708559A (en) | 1999-08-03 |
Family
ID=27360291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9708559A BR9708559A (en) | 1996-04-10 | 1997-04-01 | Denaturants for sympathomimetic amine salts |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6136864A (en) |
| EP (1) | EP0894010B1 (en) |
| JP (1) | JP2001527514A (en) |
| AR (1) | AR006571A1 (en) |
| AT (1) | ATE244019T1 (en) |
| BR (1) | BR9708559A (en) |
| CA (1) | CA2250010C (en) |
| DE (1) | DE69723248T2 (en) |
| DK (1) | DK0894010T3 (en) |
| ES (1) | ES2202605T3 (en) |
| MX (1) | MX9807594A (en) |
| NZ (1) | NZ332233A (en) |
| PE (1) | PE20011304A1 (en) |
| PT (1) | PT894010E (en) |
| SI (1) | SI0894010T1 (en) |
| TW (1) | TW522012B (en) |
| UY (1) | UY24512A1 (en) |
| WO (1) | WO1997037689A2 (en) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945125A (en) * | 1995-02-28 | 1999-08-31 | Temple University | Controlled release tablet |
| GT199900148A (en) * | 1998-09-10 | 2001-02-28 | Denaturing for the sympathomimetic amine salts. | |
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| JP4370451B2 (en) * | 2001-09-28 | 2009-11-25 | 大塚製薬株式会社 | Pharmaceutical composition |
| US7771707B2 (en) | 2004-06-12 | 2010-08-10 | Collegium Pharmaceutical, Inc. | Abuse-deterrent drug formulations |
| US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
| DE102004045037A1 (en) * | 2004-09-15 | 2006-03-16 | Basf Ag | Pharmaceutical dosage forms with difficult extractability of a sympathomimetic from the dosage form |
| US9238073B2 (en) | 2006-04-12 | 2016-01-19 | Wyeth Llc | Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive |
| SA07280459B1 (en) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | Tamper Resistant Oral Pharmaceutical Dosage Forms Comprising an Opioid Analgesic |
| ES2612032T3 (en) * | 2007-06-04 | 2017-05-11 | Shear/Kershman Laboratories, Inc. | Oral pharmaceutical forms based on inviolable lipids for opioid agonists |
| EP3064064A1 (en) * | 2009-09-30 | 2016-09-07 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse |
| US10668060B2 (en) | 2009-12-10 | 2020-06-02 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
| CN104873455B (en) | 2010-12-22 | 2023-09-12 | 普渡制药公司 | Coated Tamper Resistant Controlled Release Dosage Forms |
| CN103327969A (en) | 2010-12-23 | 2013-09-25 | 普渡制药公司 | Tamper resistant solid oral dosage forms |
| US20150238615A1 (en) * | 2011-12-12 | 2015-08-27 | Leonard Mackles | Denaturants for sympathomimetic amines |
| JP5922851B2 (en) | 2012-11-30 | 2016-05-24 | アキュラ・ファーマシューティカルズ・インコーポレーテッド | Self-controlled release of active pharmaceutical ingredients |
| WO2014123899A1 (en) | 2013-02-05 | 2014-08-14 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
| US10751287B2 (en) | 2013-03-15 | 2020-08-25 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
| AU2015237723B2 (en) | 2014-03-26 | 2018-04-26 | Sun Pharma Advanced Research Company Ltd. | Abuse deterrent immediate release biphasic matrix solid dosage form |
| US10058490B2 (en) * | 2014-12-24 | 2018-08-28 | L'oreal | Acoustically-activated cosmetic hydrogels |
| WO2017040607A1 (en) | 2015-08-31 | 2017-03-09 | Acura Pharmaceuticals, Inc. | Methods and compositions for self-regulated release of active pharmaceutical ingredient |
| US9737530B1 (en) | 2016-06-23 | 2017-08-22 | Collegium Pharmaceutical, Inc. | Process of making stable abuse-deterrent oral formulations |
| FR3059903B1 (en) * | 2016-12-08 | 2019-03-22 | Salsarulo Pharma | ORAL MEDICINE COMPRISING AN OSMOTIC LAXATIVE INCORPORATED IN A MATRIX BASED ON VEGETABLE FATS |
| CN114073689B (en) * | 2020-08-10 | 2024-01-12 | 江苏长泰药业有限公司 | Extraction-preventing pharmaceutical composition and preparation thereof |
| CN114073690B (en) * | 2020-08-10 | 2024-01-12 | 江苏长泰药业有限公司 | Extraction-preventing pharmaceutical composition containing amino acid and preparation thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3169092A (en) * | 1963-09-26 | 1965-02-09 | Richardson Merrell Inc | Stabilization of amines by tartrazine and bisulfite |
| US3773920A (en) * | 1971-07-14 | 1973-11-20 | Nikken Chemicals Co Ltd | Sustained release medicinal composition |
| GB1593261A (en) * | 1976-07-23 | 1981-07-15 | Inveresk Res Int | Controlled release suppository |
| US4493827A (en) * | 1983-11-14 | 1985-01-15 | Ronald Valle | Method of inducing sleep |
| US4601894A (en) * | 1985-03-29 | 1986-07-22 | Schering Corporation | Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate |
| US4657757A (en) * | 1985-03-29 | 1987-04-14 | Schering Corporation | Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate |
| US4689223A (en) * | 1986-04-24 | 1987-08-25 | T & R Chemicals, Inc. | Method of treating the symptoms of the common cold |
| ZA904021B (en) * | 1989-11-24 | 1991-02-27 | Van Der Linde Leon | Slimming preparations |
| US5407686A (en) * | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
| AU681672B2 (en) * | 1993-06-04 | 1997-09-04 | Warner-Lambert Company Llc | Preparations containing silicon dioxide to improve the taste thereof |
| AUPM814994A0 (en) * | 1994-09-14 | 1994-10-06 | Sterling Winthrop Inc. | Codeine-containing formulations |
| US5585108A (en) * | 1994-12-30 | 1996-12-17 | Nanosystems L.L.C. | Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays |
-
1997
- 1997-04-01 DK DK97920079T patent/DK0894010T3/en active
- 1997-04-01 US US08/937,408 patent/US6136864A/en not_active Expired - Lifetime
- 1997-04-01 MX MX9807594A patent/MX9807594A/en unknown
- 1997-04-01 AT AT97920079T patent/ATE244019T1/en not_active IP Right Cessation
- 1997-04-01 SI SI9730559T patent/SI0894010T1/en unknown
- 1997-04-01 JP JP53631297A patent/JP2001527514A/en not_active Ceased
- 1997-04-01 WO PCT/US1997/005509 patent/WO1997037689A2/en active IP Right Grant
- 1997-04-01 PT PT97920079T patent/PT894010E/en unknown
- 1997-04-01 CA CA002250010A patent/CA2250010C/en not_active Expired - Fee Related
- 1997-04-01 NZ NZ332233A patent/NZ332233A/en unknown
- 1997-04-01 DE DE69723248T patent/DE69723248T2/en not_active Expired - Lifetime
- 1997-04-01 ES ES97920079T patent/ES2202605T3/en not_active Expired - Lifetime
- 1997-04-01 BR BR9708559A patent/BR9708559A/en not_active Application Discontinuation
- 1997-04-01 EP EP97920079A patent/EP0894010B1/en not_active Expired - Lifetime
- 1997-04-09 PE PE2001001077A patent/PE20011304A1/en not_active Application Discontinuation
- 1997-04-09 UY UY24512A patent/UY24512A1/en not_active IP Right Cessation
- 1997-04-09 AR ARP970101397A patent/AR006571A1/en unknown
- 1997-04-10 TW TW086104620A patent/TW522012B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001527514A (en) | 2001-12-25 |
| DE69723248T2 (en) | 2004-05-27 |
| US6136864A (en) | 2000-10-24 |
| WO1997037689A2 (en) | 1997-10-16 |
| WO1997037689A3 (en) | 1997-12-04 |
| SI0894010T1 (en) | 2003-10-31 |
| ATE244019T1 (en) | 2003-07-15 |
| MX9807594A (en) | 1999-03-31 |
| EP0894010B1 (en) | 2003-07-02 |
| NZ332233A (en) | 1999-11-29 |
| AU2436097A (en) | 1997-10-29 |
| ES2202605T3 (en) | 2004-04-01 |
| AR006571A1 (en) | 1999-09-08 |
| PT894010E (en) | 2003-11-28 |
| CA2250010A1 (en) | 1997-10-16 |
| EP0894010A2 (en) | 1999-02-03 |
| UY24512A1 (en) | 2001-08-27 |
| TW522012B (en) | 2003-03-01 |
| DE69723248D1 (en) | 2003-08-07 |
| PE20011304A1 (en) | 2002-01-18 |
| DK0894010T3 (en) | 2003-10-27 |
| AU711752B2 (en) | 1999-10-21 |
| CA2250010C (en) | 2008-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: COM BASE NO ARTIGO 37/LPI, EM COMBINACAO COM O ARTIGO 8O/LPI, OPINO PELO INDEFERIMENTO DO PRESENTEPEDIDO DE PATENTE. |
|
| B25D | Requested change of name of applicant approved |
Owner name: WARNER-LAMBERT COMPANY LLC (US) Free format text: ALTERADO DE: WARNER-LAMBERT COMPANY |