BR9704968A - Processos para inibir o crescimento de células de mamíferos e a montagem de microtúbulos e para tratar uma doença que responde à inibição da mitose e composição farmacêutica - Google Patents
Processos para inibir o crescimento de células de mamíferos e a montagem de microtúbulos e para tratar uma doença que responde à inibição da mitose e composição farmacêuticaInfo
- Publication number
- BR9704968A BR9704968A BR9704968A BR9704968A BR9704968A BR 9704968 A BR9704968 A BR 9704968A BR 9704968 A BR9704968 A BR 9704968A BR 9704968 A BR9704968 A BR 9704968A BR 9704968 A BR9704968 A BR 9704968A
- Authority
- BR
- Brazil
- Prior art keywords
- microtubules
- mitosis
- responds
- inhibition
- inhibit
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2758396P | 1996-10-03 | 1996-10-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9704968A true BR9704968A (pt) | 1998-10-27 |
Family
ID=21838567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9704968A BR9704968A (pt) | 1996-10-03 | 1997-10-02 | Processos para inibir o crescimento de células de mamíferos e a montagem de microtúbulos e para tratar uma doença que responde à inibição da mitose e composição farmacêutica |
Country Status (9)
Country | Link |
---|---|
US (1) | US6140362A (pt) |
EP (1) | EP0834311A1 (pt) |
JP (1) | JPH10114651A (pt) |
KR (1) | KR19980032504A (pt) |
AU (1) | AU737454B2 (pt) |
BR (1) | BR9704968A (pt) |
CA (1) | CA2216265A1 (pt) |
IL (1) | IL121789A (pt) |
ZA (1) | ZA978494B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1229027A1 (en) * | 1996-06-28 | 2002-08-07 | Dow AgroSciences LLC | Heterocyclic N-acetonylbenzamides and their use as fungicides |
US6500405B1 (en) * | 1996-11-14 | 2002-12-31 | Dow Agrosciences Llc | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring |
ZA983331B (en) * | 1997-05-01 | 1998-10-27 | Allegheny University Of The He | Method for treating protozoal infections |
AU2090099A (en) * | 1997-12-16 | 1999-07-05 | William Darwin Garner | Reduction of uv induced skin cancer by topical amines |
JP4143787B2 (ja) | 1999-07-28 | 2008-09-03 | 味の素株式会社 | α−アミノハロメチルケトン誘導体の製造方法 |
US20050095663A1 (en) * | 2002-06-17 | 2005-05-05 | Young David H. | Process for screening fungitoxic compounds |
US7375093B2 (en) | 2002-07-05 | 2008-05-20 | Intrexon Corporation | Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
UA87884C2 (uk) * | 2004-12-03 | 2009-08-25 | Мерк Энд Ко., Инк. | Безводна кристалічна калієва сіль інгібітора віл-інтегрази |
US8247436B2 (en) | 2010-03-19 | 2012-08-21 | Novartis Ag | Pyridine and pyrazine derivative for the treatment of CF |
CN113387781A (zh) * | 2021-07-16 | 2021-09-14 | 大连凯飞化学股份有限公司 | 一种α-卤代酮类化合物的制备方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3661991A (en) * | 1969-05-29 | 1972-05-09 | Rohm & Haas | N-(1,1-dialkyl-3-chloroacetonyl) benzamides |
JPS5622790A (en) * | 1979-07-31 | 1981-03-03 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
FR2488800A1 (fr) * | 1980-08-19 | 1982-02-26 | Terumo Corp | Extraits d'ecorce du margousier possedant une activite antineoplastique |
WO1982001188A1 (en) * | 1980-10-08 | 1982-04-15 | Takeda Chemical Industries Ltd | 4,5-deoxymaytansinoide compounds and process for preparing same |
EP0123441B1 (en) * | 1983-03-30 | 1990-10-03 | Lilly Industries Limited | Vincaleukoblastine derivatives |
US4863940A (en) * | 1984-07-26 | 1989-09-05 | Rohm And Haas | N-acetonyl-substituted amides and phytopathogenic fungicidal use thereof |
US4822902A (en) * | 1984-07-26 | 1989-04-18 | Rohm And Haas Company | N-acetonylbenzamides and their use as fungicides |
US4701406A (en) * | 1984-11-16 | 1987-10-20 | Trustees Of Boston University | Assay for the detection of epigenetic toxic (non-genotoxic) substances |
US4675400A (en) * | 1985-06-17 | 1987-06-23 | Eli Lilly And Company | Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids |
US4707498A (en) * | 1986-01-14 | 1987-11-17 | Merrell Dow Pharmaceuticals Inc. | Fluorinated diaminoalkyne derivatives |
US4904697A (en) * | 1987-04-09 | 1990-02-27 | Merrell Dow Pharmaceuticals Inc. | Controlling the growth of certain tumor tissue with chalcone derivatives |
US5003056A (en) * | 1987-12-24 | 1991-03-26 | Nippon Kayaku Kabushiki Kaisha | Antibiotic NK86-0279, process for production of the same and application of the same |
US5238941A (en) * | 1988-03-25 | 1993-08-24 | Ciba-Geigy Corporation | Arylhydrazones and pharmaceutical compositions thereof |
US4950761A (en) * | 1988-04-04 | 1990-08-21 | Southern Research Institute | (S)-[6-amino-4-[(1-methyl-2-oxo-2 phenyl-ethyl amino]-5-nitro-2-pyridinyl]ca |
US5304572A (en) * | 1992-12-01 | 1994-04-19 | Rohm And Haas Company | N-acetonylbenzamides and their use as fungicides |
US5254584A (en) * | 1992-12-18 | 1993-10-19 | Rohm And Haas Company | N-acetonylbenzamides and their use as fungicides |
-
1997
- 1997-09-17 IL IL12178997A patent/IL121789A/en not_active IP Right Cessation
- 1997-09-19 AU AU38356/97A patent/AU737454B2/en not_active Ceased
- 1997-09-22 ZA ZA9708494A patent/ZA978494B/xx unknown
- 1997-09-23 CA CA002216265A patent/CA2216265A1/en not_active Abandoned
- 1997-09-29 US US08/939,516 patent/US6140362A/en not_active Expired - Fee Related
- 1997-09-30 EP EP97307683A patent/EP0834311A1/en not_active Withdrawn
- 1997-10-02 KR KR1019970050916A patent/KR19980032504A/ko not_active Application Discontinuation
- 1997-10-02 BR BR9704968A patent/BR9704968A/pt unknown
- 1997-10-03 JP JP9286218A patent/JPH10114651A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JPH10114651A (ja) | 1998-05-06 |
IL121789A (en) | 2001-06-14 |
AU3835697A (en) | 1998-04-09 |
EP0834311A1 (en) | 1998-04-08 |
AU737454B2 (en) | 2001-08-23 |
US6140362A (en) | 2000-10-31 |
CA2216265A1 (en) | 1998-04-03 |
MX9707574A (es) | 1998-06-28 |
ZA978494B (en) | 1998-03-26 |
IL121789A0 (en) | 1998-02-22 |
KR19980032504A (ko) | 1998-07-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A , 7A E 8A ANUIDADES. |