BR9508026A - Acetogeninas e derivados bioativos - Google Patents

Acetogeninas e derivados bioativos

Info

Publication number
BR9508026A
BR9508026A BR9508026A BR9508026A BR9508026A BR 9508026 A BR9508026 A BR 9508026A BR 9508026 A BR9508026 A BR 9508026A BR 9508026 A BR9508026 A BR 9508026A BR 9508026 A BR9508026 A BR 9508026A
Authority
BR
Brazil
Prior art keywords
acetogenins
bioactive derivatives
bioactive
derivatives
Prior art date
Application number
BR9508026A
Other languages
English (en)
Inventor
Jerry L Mclaughlin
Zhe-Ming Gu
Geng-Xian Zhao
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of BR9508026A publication Critical patent/BR9508026A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58One oxygen atom, e.g. butenolide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BR9508026A 1994-06-14 1995-06-13 Acetogeninas e derivados bioativos BR9508026A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/259,383 US5536848A (en) 1994-06-14 1994-06-14 Bioactive acetogenins and derivatives
PCT/US1995/007490 WO1995034544A1 (en) 1994-06-14 1995-06-13 Bioactive acetogenins and derivatives

Publications (1)

Publication Number Publication Date
BR9508026A true BR9508026A (pt) 1997-09-02

Family

ID=22984722

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9508026A BR9508026A (pt) 1994-06-14 1995-06-13 Acetogeninas e derivados bioativos

Country Status (8)

Country Link
US (2) US5536848A (pt)
EP (1) EP0766679A4 (pt)
JP (1) JPH10504533A (pt)
CN (1) CN1159190A (pt)
AU (1) AU689912B2 (pt)
BR (1) BR9508026A (pt)
CA (1) CA2192977A1 (pt)
WO (1) WO1995034544A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536848A (en) * 1994-06-14 1996-07-16 Purdue Research Foundation Bioactive acetogenins and derivatives
US5955497A (en) * 1997-02-25 1999-09-21 Purdue Research Foundation Bioactive acetogenins
CN1109678C (zh) * 1997-04-09 2003-05-28 中国科学院上海有机化学研究所 一种番荔枝内酯类似物及其用途
US6150540A (en) * 1998-11-02 2000-11-21 Hughes Institute Versatile intermediate for annonaceous acetogenins
CN1095465C (zh) * 1999-12-24 2002-12-04 中国科学院上海有机化学研究所 手性番荔枝内酯类化合物,合成方法及其用途
US20040101584A1 (en) * 2002-11-22 2004-05-27 Mclaughlin Jerry Loren Control of cancer with annonaceous extracts
US8669292B2 (en) * 2005-12-23 2014-03-11 Orion Therapeutics, Llc Therapeutic formulation
US7537774B2 (en) * 2005-12-23 2009-05-26 Orion Therapeautics, Llc Therapeutic formulation
JP2013508352A (ja) * 2009-10-19 2013-03-07 ライラ ニュートラシューティカルズ アセトゲニンを含む抽出物、フラクションおよび組成物ならびにそれらの応用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721727A (en) * 1986-05-06 1988-01-26 The United States Of America As Represented By The Secretary Of Agriculture Control of pests with annonaceous acetogenins
US4855319A (en) * 1986-05-06 1989-08-08 The United States Of America As Represented By The Secretary Of Agriculture Control of pests with annonaceous acetogenins
US5229419A (en) * 1989-04-11 1993-07-20 Purdue Research Foundation Chemotherapeutically active acetogenins
US5536848A (en) * 1994-06-14 1996-07-16 Purdue Research Foundation Bioactive acetogenins and derivatives

Also Published As

Publication number Publication date
CN1159190A (zh) 1997-09-10
AU689912B2 (en) 1998-04-09
WO1995034544A1 (en) 1995-12-21
US5536848A (en) 1996-07-16
US5717113A (en) 1998-02-10
AU2826095A (en) 1996-01-05
JPH10504533A (ja) 1998-05-06
EP0766679A1 (en) 1997-04-09
CA2192977A1 (en) 1995-12-21
EP0766679A4 (en) 2000-11-02

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law