BR9501187A - Preparacão de enzima purificada,método para digerir tecido desvitalizado de mamifero e método para isolar uma preparacão de enzima substancialmente purificada de um tronco de bromelaina - Google Patents

Preparacão de enzima purificada,método para digerir tecido desvitalizado de mamifero e método para isolar uma preparacão de enzima substancialmente purificada de um tronco de bromelaina

Info

Publication number
BR9501187A
BR9501187A BR9501187A BR9501187A BR9501187A BR 9501187 A BR9501187 A BR 9501187A BR 9501187 A BR9501187 A BR 9501187A BR 9501187 A BR9501187 A BR 9501187A BR 9501187 A BR9501187 A BR 9501187A
Authority
BR
Brazil
Prior art keywords
enzyme preparation
purified enzyme
digesting
isolating
mammalian tissue
Prior art date
Application number
BR9501187A
Other languages
English (en)
Inventor
John K Cini
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of BR9501187A publication Critical patent/BR9501187A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/63—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Enzymes And Modification Thereof (AREA)
BR9501187A 1994-03-23 1995-03-23 Preparacão de enzima purificada,método para digerir tecido desvitalizado de mamifero e método para isolar uma preparacão de enzima substancialmente purificada de um tronco de bromelaina BR9501187A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/217,341 US5387517A (en) 1994-03-23 1994-03-23 Thiol activated protease from stem bromelain for treating devitalized tissue

Publications (1)

Publication Number Publication Date
BR9501187A true BR9501187A (pt) 1996-03-05

Family

ID=22810658

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9501187A BR9501187A (pt) 1994-03-23 1995-03-23 Preparacão de enzima purificada,método para digerir tecido desvitalizado de mamifero e método para isolar uma preparacão de enzima substancialmente purificada de um tronco de bromelaina

Country Status (7)

Country Link
US (1) US5387517A (pt)
EP (1) EP0674001A3 (pt)
JP (1) JPH0838173A (pt)
AU (1) AU681237B2 (pt)
BR (1) BR9501187A (pt)
CA (1) CA2145131A1 (pt)
ZA (1) ZA952344B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2403433T3 (es) * 1997-02-25 2013-05-17 Sarantis Pty Ltd Componente de bromelina
CN1252101A (zh) * 1997-02-25 2000-05-03 科特克斯(英国)有限公司 菠萝蛋白酶成分
US20020102253A1 (en) 1997-02-25 2002-08-01 Mynott Tracey Lehanne Component of bromelain
US6548556B2 (en) * 2000-12-27 2003-04-15 Healthpoint, Ltd. Stable enzymatic wound debrider
WO2003090598A2 (en) * 2002-04-23 2003-11-06 Mediwound, Ltd. Apparatus and methods for enzymatic escharotomy in burn induced compartment syndrome
US7785584B2 (en) 2003-08-13 2010-08-31 Healthpoint, Ltd. Ointment wound spray
IL165334A0 (en) 2004-11-22 2006-01-15 Mediwound Ltd Debriding composition from bromelain and methods of producing same
ITMI20052076A1 (it) * 2005-10-31 2007-05-01 Stel S N C Dell Ing Ermete Riva & C Apparecchiatura per il trattamento endotonico mediante circolazione di soluzioni enzimatiche nella camera pulpare e nei canali radicolari
WO2013096337A1 (en) 2011-12-20 2013-06-27 Kci Licensing, Inc. Composition for enzymatic debridement
US9821040B2 (en) 2014-02-26 2017-11-21 Kiss My Itch Goodbye Inc Topical therapeutic compositions containing bromelain
WO2017130204A1 (en) 2016-01-31 2017-08-03 Mediwound Ltd. Debriding composition for treating wounds

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2977287A (en) * 1957-11-25 1961-03-28 Ethicon Inc Enzyme and method for preparation
US4197291A (en) * 1974-01-08 1980-04-08 Gerold K. V. Klein Hydrolytic enzyme material
US4226854A (en) * 1974-01-08 1980-10-07 Gerold K. V. Klein Debridement of devitalized tissue with hydrolytic enzyme product
US4307081A (en) * 1974-01-08 1981-12-22 Gerold K. V. Klein Enzyme mixture
US3940478A (en) * 1974-04-29 1976-02-24 Sutures, Inc. Proteolytic enzymes as adjuncts to antibiotic prophylaxis of contaminated wounds
US3983209A (en) * 1975-01-28 1976-09-28 Alza Corporation Method for treating burns
US4122158A (en) * 1976-09-23 1978-10-24 Alza Corporation Topical therapeutic preparations
US4329430A (en) * 1979-06-04 1982-05-11 Klein Gerold K V Enzyme mixture
US4286064A (en) * 1979-11-05 1981-08-25 Riker Laboratories, Inc. Process for isolating active debriding agent from bromelain
US4361551A (en) * 1979-11-05 1982-11-30 Riker Laboratories, Inc. Method of enzymatic debridement
US4276281A (en) * 1980-09-04 1981-06-30 Crikelair George F Burn treatment
SE8302268L (sv) * 1983-04-22 1984-10-23 Lars G I Hellgren Ny kombination av proteolytiska och lipolytiska enzymer lemplig som tvettkomposition
EP0115974B1 (fr) * 1983-01-05 1988-09-07 Institut Pasteur Préparation à activité collagénolytique ayant une activité élevée et compositions pharmaceutiques la contenant
US4645668A (en) * 1983-08-04 1987-02-24 Biospecifics, Nv Method for the prevention and treatment of scars with enzymes
GB2150833B (en) * 1983-12-08 1987-04-15 Ceskoslovenska Akademie Ved Proteolytic wounds dressing
GB8724728D0 (en) * 1987-10-22 1987-11-25 Genzyme Corp Cysteine proteinase

Also Published As

Publication number Publication date
EP0674001A3 (en) 1996-04-03
JPH0838173A (ja) 1996-02-13
AU681237B2 (en) 1997-08-21
CA2145131A1 (en) 1995-09-24
AU1498395A (en) 1995-10-05
EP0674001A2 (en) 1995-09-27
ZA952344B (en) 1996-09-23
US5387517A (en) 1995-02-07

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Legal Events

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FA10 Dismissal: dismissal - article 33 of industrial property law