BR9207024A - Process and uses for 4,5-DI-hydrogeldanamycin and its hydroquinone - Google Patents

Process and uses for 4,5-DI-hydrogeldanamycin and its hydroquinone

Info

Publication number
BR9207024A
BR9207024A BR9207024A BR9207024A BR9207024A BR 9207024 A BR9207024 A BR 9207024A BR 9207024 A BR9207024 A BR 9207024A BR 9207024 A BR9207024 A BR 9207024A BR 9207024 A BR9207024 A BR 9207024A
Authority
BR
Brazil
Prior art keywords
hydrogeldanamycin
hydroquinone
Prior art date
Application number
BR9207024A
Other languages
Portuguese (pt)
Inventor
Walter P Cullen
Mark T Jefferson
Mikel P Moyer
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR9207024A publication Critical patent/BR9207024A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D225/00Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/06Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BR9207024A 1992-01-06 1992-12-03 Process and uses for 4,5-DI-hydrogeldanamycin and its hydroquinone BR9207024A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81723592A 1992-01-06 1992-01-06
PCT/US1992/010189 WO1993014215A1 (en) 1992-01-06 1992-12-03 Process and uses for 4,5-dihydrogeldanamycin and its hydroquinone

Publications (1)

Publication Number Publication Date
BR9207024A true BR9207024A (en) 1995-12-05

Family

ID=25222638

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9207024A BR9207024A (en) 1992-01-06 1992-12-03 Process and uses for 4,5-DI-hydrogeldanamycin and its hydroquinone

Country Status (15)

Country Link
JP (1) JPH06510913A (en)
KR (1) KR940703923A (en)
CN (1) CN1074937A (en)
AU (1) AU3225693A (en)
BR (1) BR9207024A (en)
CA (1) CA2127457A1 (en)
CZ (1) CZ390592A3 (en)
FI (1) FI943207A0 (en)
HU (1) HU9401936D0 (en)
IL (1) IL104289A0 (en)
MX (1) MX9300011A (en)
NO (1) NO942532L (en)
PT (1) PT101169A (en)
WO (1) WO1993014215A1 (en)
ZA (1) ZA9333B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001342A1 (en) * 1993-06-29 1995-01-12 Pfizer Inc. Ansamycin derivatives as antioncogene and anticancer agents
US5932566A (en) * 1994-06-16 1999-08-03 Pfizer Inc. Ansamycin derivatives as antioncogene and anticancer agents
US6852496B1 (en) 1997-08-12 2005-02-08 Oregon Health And Science University Methods of screening for agents that promote nerve cell growth
US6872715B2 (en) 2001-08-06 2005-03-29 Kosan Biosciences, Inc. Benzoquinone ansamycins
EP1435939B1 (en) 2001-09-24 2008-02-27 Conforma Therapeutic Corporation Process for preparing 17-allyl amino geldanamycin (17-aag) and other ansamycins
EP1923061A1 (en) 2001-09-24 2008-05-21 Conforma Therapeutic Corporation Process for preparing 17-Allyl amino geldanamycin (17-AAG) and other ansamycins
JP2005530689A (en) 2002-02-08 2005-10-13 コンフォーマ・セラピューティクス・コーポレイション Ansamycins with improved pharmacological and biological properties
TW200303363A (en) * 2002-02-25 2003-09-01 Upjohn Co Process to prepare and isolate geldanamycin
WO2005009345A2 (en) 2003-06-13 2005-02-03 Kosan Biosciences, Inc. 2-desmethyl ansamycin compounds
US6855705B1 (en) 2003-11-12 2005-02-15 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US6887993B1 (en) 2003-11-12 2005-05-03 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US6875863B1 (en) 2003-11-12 2005-04-05 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US6870049B1 (en) 2003-11-12 2005-03-22 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
EP1689436A1 (en) * 2003-11-26 2006-08-16 Entelos, Inc. TREATMENT OF RHEUMATOID ARTHRITIS WITH HYPOXIA-INDUCIBLE FACTOR a ANTAGONISTS
US7282493B2 (en) 2003-12-23 2007-10-16 Infinity Pharmaceuticals, Inc. Analogs of benzoquinone-containing ansamycins and methods of use thereof
US20060019941A1 (en) * 2003-12-23 2006-01-26 Infinity Pharmaceuticals, Inc. Analogs of benzoquinone-containing ansamycins and methods of use thereof
CN1898212B (en) * 2003-12-23 2012-06-13 无限发现公司 Analogs of benzoquinone-containing ansamycins for the treatment of cancer
AU2006230447A1 (en) 2005-03-30 2006-10-05 Conforma Therapeutics Corporation Alkynyl pyrrolopyrimidines and related analogs as HSP90-inhibitors
US8492370B2 (en) * 2006-11-09 2013-07-23 Bristol-Myers Squibb Company Compounds and methods for their production
PE20081506A1 (en) 2006-12-12 2008-12-09 Infinity Discovery Inc ANSAMYCIN FORMULATIONS
CN100500668C (en) * 2006-12-19 2009-06-17 中国人民解放军军事医学科学院毒物药物研究所 Geldanamycin derivative and its preparing method and use for preparing medicine
JP2010516282A (en) 2007-01-26 2010-05-20 コーサン バイオサイエンシーズ, インコーポレイテッド Macrolactam by engineering biosynthesis
US20110034686A1 (en) * 2008-04-21 2011-02-10 Nitin Sopanrao Patil Process for Isolation and Purification of Geldanamycin
US8778921B2 (en) 2008-10-15 2014-07-15 Infinity Pharmaceuticals, Inc. Ansamycin hydroquinone compositions
CN102030764B (en) * 2010-11-12 2012-07-04 中国医学科学院医药生物技术研究所 4,5-dihydro-thiazinogeldanamycin and preparation method thereof
CN103305563B (en) * 2013-06-14 2014-12-03 湖南农业大学 Method for extracting alisamycin from streptomyces

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3595955A (en) * 1969-03-26 1971-07-27 Upjohn Co Geldanamycin and process for producing same

Also Published As

Publication number Publication date
AU3225693A (en) 1993-08-03
WO1993014215A1 (en) 1993-07-22
NO942532D0 (en) 1994-07-05
HU9401936D0 (en) 1994-09-28
CN1074937A (en) 1993-08-04
ZA9333B (en) 1994-07-05
CZ390592A3 (en) 1993-08-11
IL104289A0 (en) 1993-05-13
CA2127457A1 (en) 1993-07-22
MX9300011A (en) 1993-12-01
JPH06510913A (en) 1994-12-08
FI943207A (en) 1994-07-05
KR940703923A (en) 1994-12-12
PT101169A (en) 1994-03-31
FI943207A0 (en) 1994-07-05
NO942532L (en) 1994-07-05

Similar Documents

Publication Publication Date Title
BR9207024A (en) Process and uses for 4,5-DI-hydrogeldanamycin and its hydroquinone
BR9103195A (en) COMPOUND AND PROCESS FOR ITS PREPARATION
BR9302680A (en) PROCESS FOR HYDROFORMILATION TO PRODUCE 1,6-HEXANODIALS
BR9200100A (en) PROCESS FOR SIMULTANEOUS SACARIFICATION AND FERMENTATION
DE69313022D1 (en) Liquefaction process
BR9300739A (en) HYDRO-METALURGICAL PROCESS FOR OBTAINING TANTALO AND NIOBIO
BR9305296A (en) Sump and process for its manufacture
BR9301180A (en) PROCESS FOR THE PREPARATION OF ISOCIANS AND EMPLOYMENT
BR9302424A (en) POLYCARBONATE AND PROCESS FOR THE SAME PRODUCTION
BR9200333A (en) PISTON AND PROCESS FOR YOUR MANUFACTURE
BR9204547A (en) HYDROXYPYRIDONCARBOXAMIDES, THEIR PREPARATION AND APPLICATION PROCESS
BR9004194A (en) POLYISOCIANATES, MIXTURES, PROCESS FOR ITS PREPARATION AND EMPLOYMENT
BR9301448A (en) COMPOSITION AND PROCESS FOR ITS PREPARATION
BR9400338A (en) Process for the preparation of 1,1,1,2-tetrafluoro-2-chloroethane and pentafluorethane
BR9303670A (en) Multilayer material and process for its formation
BR9203964A (en) SOAP BAR AND PROCESS FOR ITS MANUFACTURING
BR9401483A (en) Compound and process for its preparation
BR9301676A (en) PROCESS FOR THE PREPARATION OF 1,1,1,4,4,4-HEXAFLUORBUTAN AND COMPOUNDS OBTAINED
BR9300034A (en) COMPOUND, PROCESS FOR ITS PRODUCTION AND HEALING COMPOSITION
BR9302104A (en) TRACTION BAR AND PROCESS FOR ITS CONSTRUCTION
FI934624A0 (en) ENANTIOMERA CIS-3- (4,6-DIHYDROXICROMAN-3-YLMETHYL) BENZOESYROR
BR9401490A (en) Shampoo composition and process for its production
BR9301466A (en) PROCESS FOR THE PREPARATION OF ENHANCING COMPOSITES, ENHANCING COMPOSITES, THEIR APPLICATION AND COMPOSITIONS
BR9301364A (en) POLYCARBONATE COPOLIMER AND PROCESS FOR ITS PRODUCTION
BR9100045A (en) PROCESS FOR THE PREPARATION OF 1,1,1,2,2-PENTAFLUORO-3,3-DICLOROPROPANO AND 1,1,2,2,3-PENTAFLUORO-1,3-DICLOROPROPANO

Legal Events

Date Code Title Description
FA1 Application withdrawn (art. 18(2))