BR8201782A - Microorganismo geneticamente modificado codificacao de molecula de dna oligonucleotideo dna sintetico composto com atividade de interferon processo para preparacao de material genetico e de um composto com atividade de interferon - Google Patents

Microorganismo geneticamente modificado codificacao de molecula de dna oligonucleotideo dna sintetico composto com atividade de interferon processo para preparacao de material genetico e de um composto com atividade de interferon

Info

Publication number
BR8201782A
BR8201782A BR8201782A BR8201782A BR8201782A BR 8201782 A BR8201782 A BR 8201782A BR 8201782 A BR8201782 A BR 8201782A BR 8201782 A BR8201782 A BR 8201782A BR 8201782 A BR8201782 A BR 8201782A
Authority
BR
Brazil
Prior art keywords
interferon activity
compound
codification
preparation
genetically modified
Prior art date
Application number
BR8201782A
Other languages
English (en)
Portuguese (pt)
Inventor
Keith Thurston Atherton
Edward De Maeyer
Michael Derek Edge
Alexander Fred Markham
Peter Anthony Meacock
John David Windass
Original Assignee
Ici Plc
Univ Leicester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc, Univ Leicester filed Critical Ici Plc
Publication of BR8201782A publication Critical patent/BR8201782A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR8201782A 1981-03-27 1982-03-29 Microorganismo geneticamente modificado codificacao de molecula de dna oligonucleotideo dna sintetico composto com atividade de interferon processo para preparacao de material genetico e de um composto com atividade de interferon BR8201782A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8109678 1981-03-27
GB8109919 1981-03-30
GB8112446 1981-04-22
GB8126979 1981-09-07

Publications (1)

Publication Number Publication Date
BR8201782A true BR8201782A (pt) 1983-03-01

Family

ID=27449235

Family Applications (1)

Application Number Title Priority Date Filing Date
BR8201782A BR8201782A (pt) 1981-03-27 1982-03-29 Microorganismo geneticamente modificado codificacao de molecula de dna oligonucleotideo dna sintetico composto com atividade de interferon processo para preparacao de material genetico e de um composto com atividade de interferon

Country Status (8)

Country Link
EP (1) EP0062971B1 (https=)
AU (1) AU558614B2 (https=)
BR (1) BR8201782A (https=)
DE (1) DE3280127D1 (https=)
DK (1) DK139782A (https=)
GR (1) GR77049B (https=)
IL (1) IL65399A0 (https=)
NZ (1) NZ200145A (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH657141A5 (de) * 1980-07-01 1986-08-15 Hoffmann La Roche Dns-sequenzen, rekombinante expressionsvektoren zur mikrobiellen herstellung von human-leukozyten-interferonen und transformierte mikroorganismen.
EP0098967B1 (de) * 1982-06-11 1989-08-09 Hoechst Aktiengesellschaft Verfahren zur Herstellung von obligat methylotrophen, Fremd-DNA exprimierenden Bakterien und dafür geeignete Plasmide und Wirtsorganismen
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
JPS59210890A (ja) * 1983-03-09 1984-11-29 ジエネツクス・コ−ポレイシヨン ハイブリツドプラスミド
US4656132A (en) * 1984-03-28 1987-04-07 Cetus Corporation Method of improving the yield of heterologous protein produced by cultivating recombinant bacteria
GB8417915D0 (en) * 1984-07-13 1984-08-15 Ici Plc Microorganisms
SU1364343A1 (ru) * 1984-07-13 1988-01-07 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Способ получени человеческого лейкоцитарного интерферона альфа-2
EP0173935A1 (en) * 1984-08-31 1986-03-12 University Patents, Inc. Hybrid lymphoblastoid-leukocyte human interferons
EP0194006B1 (en) * 1985-02-01 1992-04-29 Imperial Chemical Industries Plc Analogous interferon polypeptides, process for their preparation and pharmaceutical compositions containing them
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
US6288042B1 (en) 1993-04-23 2001-09-11 Aronex Pharmaceuticals, Inc. Anti-viral guanosine-rich tetrad forming oligonucleotides
FR2823220B1 (fr) 2001-04-04 2003-12-12 Genodyssee Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2003926B (en) * 1977-09-08 1982-03-17 Ici Ltd Microbiological process
DE2848051A1 (de) * 1977-11-08 1979-05-10 Genentech Inc Synthetische dna und verfahren zu ihrer herstellung
IN150740B (https=) * 1978-11-24 1982-12-04 Hoffmann La Roche
FI77877C (fi) * 1979-04-20 1989-05-10 Technobiotic Ltd Foerfarande foer framstaellning och rening av human le-formig interferonprotein.
AU538665B2 (en) * 1979-10-30 1984-08-23 Juridical Foundation, Japanese Foundation For Cancer Research Human interferon dna
IE54096B1 (en) * 1980-01-08 1989-06-21 Biogen Nv Dn sequences, recombinant dna molecules and processes for producing human interferon - like polypeptides
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain

Also Published As

Publication number Publication date
EP0062971A3 (en) 1983-08-10
NZ200145A (en) 1985-07-12
IL65399A0 (en) 1982-07-30
DK139782A (da) 1982-09-28
DE3280127D1 (de) 1990-04-12
EP0062971A2 (en) 1982-10-20
GR77049B (https=) 1984-09-05
AU558614B2 (en) 1987-02-05
AU8192382A (en) 1982-09-30
EP0062971B1 (en) 1990-03-07

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