BR112023025125A2 - Formas cristalinas, composições que contêm as mesmas, e métodos de uso das mesmas - Google Patents
Formas cristalinas, composições que contêm as mesmas, e métodos de uso das mesmasInfo
- Publication number
- BR112023025125A2 BR112023025125A2 BR112023025125A BR112023025125A BR112023025125A2 BR 112023025125 A2 BR112023025125 A2 BR 112023025125A2 BR 112023025125 A BR112023025125 A BR 112023025125A BR 112023025125 A BR112023025125 A BR 112023025125A BR 112023025125 A2 BR112023025125 A2 BR 112023025125A2
- Authority
- BR
- Brazil
- Prior art keywords
- crystalline forms
- methods
- compositions containing
- salts
- salt
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical class OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 150000003467 sulfuric acid derivatives Chemical class 0.000 abstract 2
- 150000004677 hydrates Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Fertilizers (AREA)
Abstract
ormas cristalinas, composições que contêm as mesmas, e métodos de uso das mesmas. a presente invenção se refere a formas cristalinas do composto da estrutura (i) ou um sal de sulfato, um sal de hemissulfato, ou um sal de sulfato de hidrogênio do mesmo, ou um hidrato do mesmo. também são divulgados sais de sulfato, sais de hemissulfato e sais de sulfato de hidrogênio do composto da fórmula (i), e hidratos do mesmo. (i)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163197131P | 2021-06-04 | 2021-06-04 | |
| PCT/CA2022/050892 WO2022251971A1 (en) | 2021-06-04 | 2022-06-03 | Crystalline forms, compositions containing same, and methods of their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023025125A2 true BR112023025125A2 (pt) | 2024-02-27 |
Family
ID=84322546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023025125A BR112023025125A2 (pt) | 2021-06-04 | 2022-06-03 | Formas cristalinas, composições que contêm as mesmas, e métodos de uso das mesmas |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP4347593A1 (pt) |
| JP (1) | JP2024520141A (pt) |
| KR (1) | KR20240017897A (pt) |
| CN (1) | CN117794931A (pt) |
| AU (1) | AU2022284632A1 (pt) |
| BR (1) | BR112023025125A2 (pt) |
| CA (1) | CA3220976A1 (pt) |
| IL (1) | IL309051A (pt) |
| WO (1) | WO2022251971A1 (pt) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100048923A1 (en) * | 2005-10-21 | 2010-02-25 | Hiroshi Nishida | ATR Inhibitor |
| CN112142744A (zh) * | 2019-06-28 | 2020-12-29 | 上海瑛派药业有限公司 | 取代的稠合杂芳双环化合物作为激酶抑制剂及其应用 |
| MX2022000854A (es) * | 2019-07-22 | 2022-02-10 | Repare Therapeutics Inc | Derivados de 2-morfolinopiridina sustituidos como inhibidores de la cinasa atr. |
-
2022
- 2022-06-03 BR BR112023025125A patent/BR112023025125A2/pt unknown
- 2022-06-03 WO PCT/CA2022/050892 patent/WO2022251971A1/en active Application Filing
- 2022-06-03 AU AU2022284632A patent/AU2022284632A1/en active Pending
- 2022-06-03 IL IL309051A patent/IL309051A/en unknown
- 2022-06-03 EP EP22814660.1A patent/EP4347593A1/en active Pending
- 2022-06-03 CA CA3220976A patent/CA3220976A1/en active Pending
- 2022-06-03 JP JP2023574544A patent/JP2024520141A/ja active Pending
- 2022-06-03 KR KR1020247000050A patent/KR20240017897A/ko unknown
- 2022-06-03 CN CN202280054290.0A patent/CN117794931A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022251971A1 (en) | 2022-12-08 |
| JP2024520141A (ja) | 2024-05-21 |
| CN117794931A (zh) | 2024-03-29 |
| IL309051A (en) | 2024-02-01 |
| AU2022284632A1 (en) | 2023-12-07 |
| CA3220976A1 (en) | 2022-12-08 |
| EP4347593A1 (en) | 2024-04-10 |
| KR20240017897A (ko) | 2024-02-08 |
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