BR112023018518A2 - Compostos para uso no tratamento e prevenção de covid-19 - Google Patents

Compostos para uso no tratamento e prevenção de covid-19

Info

Publication number
BR112023018518A2
BR112023018518A2 BR112023018518A BR112023018518A BR112023018518A2 BR 112023018518 A2 BR112023018518 A2 BR 112023018518A2 BR 112023018518 A BR112023018518 A BR 112023018518A BR 112023018518 A BR112023018518 A BR 112023018518A BR 112023018518 A2 BR112023018518 A2 BR 112023018518A2
Authority
BR
Brazil
Prior art keywords
covid
prevention
treatment
compounds
cov
Prior art date
Application number
BR112023018518A
Other languages
English (en)
Inventor
Thomas Szekeres
Walter Jager
Original Assignee
Thomas Szekeres
Walter Jager
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Szekeres, Walter Jager filed Critical Thomas Szekeres
Publication of BR112023018518A2 publication Critical patent/BR112023018518A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/205—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings
    • C07C39/21—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings with at least one hydroxy group on a non-condensed ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

compostos para uso no tratamento e prevenção de covid-19. a invenção revela um composto com a fórmula geral i em que r1 a r6 são idênticos ou não e são h, oh- ou or7, em que r7 é um grupo c1 a c3 alquila ou um grupo c1 a c4 acila, com a condição de que pelo menos quatro de r1 a r6 são diferentes de h, para uso no tratamento e prevenção de covid-19 em um indivíduo humano, especialmente para inibir sars-cov-2.
BR112023018518A 2021-03-25 2022-03-14 Compostos para uso no tratamento e prevenção de covid-19 BR112023018518A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21164854 2021-03-25
EP21164852 2021-03-25
PCT/EP2022/056429 WO2022200086A1 (en) 2021-03-25 2022-03-14 Compounds for use in the treatment and prevention of covid- 19

Publications (1)

Publication Number Publication Date
BR112023018518A2 true BR112023018518A2 (pt) 2023-10-10

Family

ID=80937289

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023018518A BR112023018518A2 (pt) 2021-03-25 2022-03-14 Compostos para uso no tratamento e prevenção de covid-19

Country Status (9)

Country Link
US (1) US20240166587A1 (pt)
EP (1) EP4313010A1 (pt)
JP (1) JP2024514770A (pt)
KR (1) KR20230159460A (pt)
AU (1) AU2022243973A1 (pt)
BR (1) BR112023018518A2 (pt)
CA (1) CA3207805A1 (pt)
MX (1) MX2023009901A (pt)
WO (1) WO2022200086A1 (pt)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1351912A2 (en) 2000-12-21 2003-10-15 Cancer Research Ventures Limited Substituted stilbenes, their reactions and anticancer activity
AU2002226225B2 (en) 2001-01-18 2008-03-20 Dermavant Sciences GmbH Novel 1,2-diphenylethene derivatives for treatment of immune diseases
EP1654210B1 (de) 2003-08-14 2008-07-30 Thomas Szekeres Stilben-derivate und deren verwendung in arzneimitteln
AT502078A1 (de) 2005-07-04 2007-01-15 Univ Wien Med Verwendung von stilbenderivaten zur herstellung von arzneimitteln für die behandlung solider tumore
CN1331856C (zh) 2005-08-05 2007-08-15 大连理工大学 多羟基茋类化合物的制备和抑制sars病毒药物的用途
CN112912074A (zh) 2018-08-17 2021-06-04 奥古斯塔大学研究所公司 Egcg-棕榈酸酯组合物及其使用方法
CN111228343B (zh) 2020-02-12 2022-01-14 昆明翔昊科技有限公司 曲札提取物及其在制备预防和/或治疗病毒性肺炎的药物的应用

Also Published As

Publication number Publication date
US20240166587A1 (en) 2024-05-23
MX2023009901A (es) 2023-09-04
EP4313010A1 (en) 2024-02-07
CA3207805A1 (en) 2022-09-29
JP2024514770A (ja) 2024-04-03
AU2022243973A1 (en) 2023-09-14
WO2022200086A1 (en) 2022-09-29
KR20230159460A (ko) 2023-11-21

Similar Documents

Publication Publication Date Title
BR112022020841A2 (pt) Inibidores de kras tricíclicos fundidos
CY1123466T1 (el) Ν-πιπεριδινυλ ακεταμιδιου παραγωγα ως αναστολεις διαυλου ασβεστιου
EP4026835A3 (en) Pd-1/pd-l1 inhibitors
MD3319611T2 (ro) Oxisteroli și metode de utilizare a acestora
MA45598B1 (fr) Stéroles 24-hydroxylés substitués en position 11 pour le traitement des maladies liées au récepteur nmda
MD3319612T2 (ro) Oxisteroli și metode de utilizare a acestora
BR112015010919A2 (pt) composição, composição reticulada e artigo
BR112022000503A2 (pt) Compostos úteis para tratar infecções por vírus influenza
BRPI0510059B8 (pt) inibidores da transcriptase reversa não-nucleosídica e seus usos
CL2008000959A1 (es) Compuestos derivados de 1,2,4-tiadiazina o 1,4-tiazina; composiciones farmaceuticas que los contienen; y su uso para la prevencion y/o tratamiento de infecciones producidas por el virus de la hepatitis c.
CL2017002856A1 (es) Compuestos de tioéter como inhibidores de la nitrificación
BR112018073626A2 (pt) compostos para promover o crescimento capilar e/ou inibir ou retardar a perda de cabelo em humanos e composições para tais usos
BRPI0513720A (pt) compostos, uso de um composto, agente adequado para combater fungos nocivos, e, processo para combater fungos fitopatogênicos
BR112021026682A2 (pt) Compostos e métodos para inibir eif4e
MA39315A1 (fr) Dérivés de pyridazine à utiliser dans la prévention ou le traitement d'un trouble ataxique
ECSP23057264A (es) Inhibidores de cdk2 y métodos de uso de los mismos
MX2021010700A (es) Compuestos utiles en la terapia del vih.
CO2022000270A2 (es) Inhibidores de enzimas
CO2022000266A2 (es) Inhibidores de enzimas
PH12021550832A1 (en) Combination of small molecule cd-47 inhibitors with other anti-cancer agents
BR112017023144A2 (pt) composições cosméticas compreendendo ésteres de estolídeo e usos para o tratamento capilar
BR112021014406A2 (pt) Derivados de tiazolopiridina como antagonistas de receptor de adenosina
BR112023025789A2 (pt) Nitroxolina para uso no tratamento de neurofibroma cutâneo
BR112023018518A2 (pt) Compostos para uso no tratamento e prevenção de covid-19
MX2020009022A (es) Uso de alcoxipirazoles como inhibidores de la nitrificacion.