BR112023000788A2 - Métodos de tratamento de condições que respondem à terapia com óxido nítrico - Google Patents

Métodos de tratamento de condições que respondem à terapia com óxido nítrico

Info

Publication number
BR112023000788A2
BR112023000788A2 BR112023000788A BR112023000788A BR112023000788A2 BR 112023000788 A2 BR112023000788 A2 BR 112023000788A2 BR 112023000788 A BR112023000788 A BR 112023000788A BR 112023000788 A BR112023000788 A BR 112023000788A BR 112023000788 A2 BR112023000788 A2 BR 112023000788A2
Authority
BR
Brazil
Prior art keywords
nitric oxide
treatment
methods
conditions
ppm
Prior art date
Application number
BR112023000788A
Other languages
English (en)
Inventor
REGEV Gilly
C Miller Christopher
Original Assignee
Sanotize Res And Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanotize Res And Development Corp filed Critical Sanotize Res And Development Corp
Publication of BR112023000788A2 publication Critical patent/BR112023000788A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

MÉTODOS DE TRATAMENTO DE CONDIÇÕES QUE RESPONDEM À TERAPIA COM ÓXIDO NÍTRICO. Composições e métodos de tratamento de condições em um indivíduo que respondem ao tratamento com óxido nítrico (NO) são divulgados e descritos. Tais composições podem incluir uma combinação de um composto de liberação de óxido nítrico, um agente acidificante e um carreador em quantidades que liberam de cerca de 1 ppm*min/mL a cerca de 500 ppm*min/mL NO com base em 1 mL da composição quando medida liberando NO da composição por um período de 30 minutos em um fluxo de gás de arraste substancialmente inerte a uma vazão de 1 litro por minuto e uma pressão de 1 atmosfera, acoplado a um detector de quimioluminescência.
BR112023000788A 2020-07-16 2021-07-16 Métodos de tratamento de condições que respondem à terapia com óxido nítrico BR112023000788A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063052805P 2020-07-16 2020-07-16
PCT/IB2021/000505 WO2022013614A1 (en) 2020-07-16 2021-07-16 Methods of treating conditions responsive to nitric oxide therapy

Publications (1)

Publication Number Publication Date
BR112023000788A2 true BR112023000788A2 (pt) 2023-05-09

Family

ID=79556044

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023000788A BR112023000788A2 (pt) 2020-07-16 2021-07-16 Métodos de tratamento de condições que respondem à terapia com óxido nítrico

Country Status (9)

Country Link
US (1) US20230285447A1 (pt)
EP (1) EP4125941A4 (pt)
JP (1) JP2023533588A (pt)
CN (1) CN116615188A (pt)
AU (1) AU2021307675A1 (pt)
BR (1) BR112023000788A2 (pt)
CA (1) CA3186075A1 (pt)
MX (1) MX2023000714A (pt)
WO (1) WO2022013614A1 (pt)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709681B2 (en) * 1995-02-17 2004-03-23 Aberdeen University Acidified nitrite as an antimicrobial agent
GB0119011D0 (en) * 2001-08-03 2001-09-26 Univ Aberdeen Treatment of nail infections
WO2011155887A1 (en) * 2010-06-07 2011-12-15 Topical Pharma Ab Kit for the treatment of onychomycosis by nitric oxide
CN103690490B (zh) * 2012-08-23 2017-11-17 尼奥克斯(文莱)控股有限公司 基于微囊化化学试剂延时产生一氧化氮的系统和方法
AU2014337031A1 (en) * 2013-10-18 2016-06-02 Bovicor Pharmatech Inc. Preparation and delivery of sustained nitric oxide releasing solutions
AU2015229626B2 (en) * 2014-03-14 2021-05-20 Sanotize Research And Development Corp. Treating diseases using nitric oxide releasing solutions
CA2942841A1 (en) * 2014-03-14 2015-09-17 Bovicor Pharmatech Inc. Nitric oxide treatment of bovine respiratory disease complex and other respiratory conditions
US20170151277A1 (en) * 2015-09-04 2017-06-01 Bovicor Pharmatech Inc. Enhanced immune response in cattle upon treatment with nitric oxide
US20190076468A1 (en) * 2017-09-11 2019-03-14 Christopher C. Miller Enhanced immune response upon treatment with nitric oxide
WO2019175674A2 (en) * 2018-03-13 2019-09-19 Regev Gilly Nitric oxide releasing compositions
WO2020035739A1 (en) * 2018-08-14 2020-02-20 Regev Gilly Devices and methods for quantifying nitric oxide
CA3116166A1 (en) * 2018-10-12 2020-04-16 Sanotize Research And Development Corp. Gas-evolving compositions and container and delivery systems

Also Published As

Publication number Publication date
JP2023533588A (ja) 2023-08-03
MX2023000714A (es) 2023-02-14
CA3186075A1 (en) 2022-01-20
WO2022013614A4 (en) 2022-03-31
EP4125941A1 (en) 2023-02-08
US20230285447A1 (en) 2023-09-14
AU2021307675A1 (en) 2023-02-16
EP4125941A4 (en) 2024-04-10
CN116615188A (zh) 2023-08-18
WO2022013614A1 (en) 2022-01-20

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