BR112022021129A2 - Mistura em pó oral com partículas de tamanho pequeno - Google Patents

Mistura em pó oral com partículas de tamanho pequeno

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Publication number
BR112022021129A2
BR112022021129A2 BR112022021129A BR112022021129A BR112022021129A2 BR 112022021129 A2 BR112022021129 A2 BR 112022021129A2 BR 112022021129 A BR112022021129 A BR 112022021129A BR 112022021129 A BR112022021129 A BR 112022021129A BR 112022021129 A2 BR112022021129 A2 BR 112022021129A2
Authority
BR
Brazil
Prior art keywords
particles
powder mixture
sugar alcohol
small size
types
Prior art date
Application number
BR112022021129A
Other languages
English (en)
Inventor
Wittorff Helle
Nohr Pedersen Christine
Original Assignee
Fertin Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fertin Pharma As filed Critical Fertin Pharma As
Publication of BR112022021129A2 publication Critical patent/BR112022021129A2/pt

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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
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    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K2800/41—Particular ingredients further characterized by their size
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/524—Preservatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
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  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Packages (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

MISTURA EM PÓ ORAL COM PARTÍCULAS DE TAMANHO PEQUENO. A presente invenção refere-se a uma mistura em pó para distribuição oral de ingredientes ativos, a mistura em pó compreendendo uma população de partículas e um ou mais ingredientes ativos, a população de partículas incluindo pelo menos dois tipos de partículas de álcool de açúcar, sendo que: pelo menos um dos referidos pelo menos dois tipos de partículas de álcool de açúcar compreendem i) partículas de álcool de açúcar não diretamente compressíveis (não DC) ou ii) partículas de álcool de açúcar diretamente compressíveis (DC) que não são partículas de álcool de açúcar granuladas; pelo menos um dos referidos pelo menos dois tipos de partículas de álcool de açúcar tendo um tamanho de partícula com mais de 50% das partículas tendo menos de 250 mícrons; pelo menos um dos referidos pelo menos dois tipos de partículas de álcool de açúcar estando presente em uma quantidade de pelo menos 20% em peso da mistura em pó.
BR112022021129A 2020-05-08 2021-04-30 Mistura em pó oral com partículas de tamanho pequeno BR112022021129A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA202070298 2020-05-08
PCT/DK2021/050137 WO2021223825A1 (en) 2020-05-08 2021-04-30 Oral powder mixture with small sized particles

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BR112022021602A BR112022021602A2 (pt) 2020-05-08 2021-04-30 Embalagem flowpack para entrega oral de ingredientes ativos

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EP (3) EP4146166A1 (pt)
JP (3) JP2023525277A (pt)
KR (1) KR20230009447A (pt)
CN (3) CN115515562A (pt)
AU (3) AU2021268062A1 (pt)
BR (2) BR112022021129A2 (pt)
CA (3) CA3176461A1 (pt)
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WO2024002447A1 (en) * 2022-06-30 2024-01-04 Fertin Pharma A/S Flowpack with composition for improved taste masking of actives

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KR20230009447A (ko) 2023-01-17
JP2023525279A (ja) 2023-06-15
MX2022014002A (es) 2022-11-30
EP4146164A1 (en) 2023-03-15
JP2023525275A (ja) 2023-06-15
EP4146166A1 (en) 2023-03-15
US20210346257A1 (en) 2021-11-11
JP2023525277A (ja) 2023-06-15
WO2021223825A1 (en) 2021-11-11
US20210346295A1 (en) 2021-11-11
WO2021223824A1 (en) 2021-11-11
US20210346263A1 (en) 2021-11-11
BR112022021602A2 (pt) 2022-12-06
WO2021223826A1 (en) 2021-11-11
AU2021266856A1 (en) 2022-11-17
EP4146165A1 (en) 2023-03-15
AU2021268062A1 (en) 2022-11-17
CA3174693A1 (en) 2021-11-11
CA3175478A1 (en) 2021-11-11
CA3176461A1 (en) 2021-11-11
CN115515562A (zh) 2022-12-23
AU2021268903A1 (en) 2022-11-17
CN115515563A (zh) 2022-12-23

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