BR112022017770A2 - Polinucleotídeo isolado; painel de polinucleotídeos isolados; kit que compreende o polinucleotídeo isolado ou painel; microarranjo; reagente; kit que compreende o reagente; kit que compreende o polinucleotídeo isolado ou painel; método de diagnóstico complementar; método para classificar um indivíduo para elegibilidade para um tratamento; método para rastrear um indivíduo ou uma população de indivíduos para um tratamento; método para monitorar um indivíduo durante um tratamento; método para identificar um alvo de fármaco; método para o tratamento de doença ou transtorno do sistema nervoso central (snc) em um indivíduo; uso - Google Patents
Polinucleotídeo isolado; painel de polinucleotídeos isolados; kit que compreende o polinucleotídeo isolado ou painel; microarranjo; reagente; kit que compreende o reagente; kit que compreende o polinucleotídeo isolado ou painel; método de diagnóstico complementar; método para classificar um indivíduo para elegibilidade para um tratamento; método para rastrear um indivíduo ou uma população de indivíduos para um tratamento; método para monitorar um indivíduo durante um tratamento; método para identificar um alvo de fármaco; método para o tratamento de doença ou transtorno do sistema nervoso central (snc) em um indivíduo; usoInfo
- Publication number
- BR112022017770A2 BR112022017770A2 BR112022017770A BR112022017770A BR112022017770A2 BR 112022017770 A2 BR112022017770 A2 BR 112022017770A2 BR 112022017770 A BR112022017770 A BR 112022017770A BR 112022017770 A BR112022017770 A BR 112022017770A BR 112022017770 A2 BR112022017770 A2 BR 112022017770A2
- Authority
- BR
- Brazil
- Prior art keywords
- individual
- treatment
- kit
- panel
- isolated polynucleotide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202062986603P | 2020-03-06 | 2020-03-06 | |
PCT/US2021/019265 WO2021178166A1 (en) | 2020-03-06 | 2021-02-23 | Compositions and methods for assessing the efficacy of inhibitors of neurotransmitter transporters |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022017770A2 true BR112022017770A2 (pt) | 2022-11-29 |
Family
ID=77613738
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022017770A BR112022017770A2 (pt) | 2020-03-06 | 2021-02-23 | Polinucleotídeo isolado; painel de polinucleotídeos isolados; kit que compreende o polinucleotídeo isolado ou painel; microarranjo; reagente; kit que compreende o reagente; kit que compreende o polinucleotídeo isolado ou painel; método de diagnóstico complementar; método para classificar um indivíduo para elegibilidade para um tratamento; método para rastrear um indivíduo ou uma população de indivíduos para um tratamento; método para monitorar um indivíduo durante um tratamento; método para identificar um alvo de fármaco; método para o tratamento de doença ou transtorno do sistema nervoso central (snc) em um indivíduo; uso |
Country Status (13)
Country | Link |
---|---|
US (1) | US20230193388A1 (ko) |
EP (1) | EP4106872A4 (ko) |
JP (1) | JP2023515665A (ko) |
KR (1) | KR20230005816A (ko) |
CN (1) | CN115515680A (ko) |
AR (1) | AR121515A1 (ko) |
AU (1) | AU2021231683A1 (ko) |
BR (1) | BR112022017770A2 (ko) |
CA (1) | CA3174572A1 (ko) |
IL (1) | IL296168A (ko) |
MX (1) | MX2022010816A (ko) |
TW (1) | TW202146660A (ko) |
WO (1) | WO2021178166A1 (ko) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114848835B (zh) * | 2022-03-22 | 2023-08-25 | 暨南大学 | 塞来昔布的聚乙二醇修饰及连接叶酸基团的靶向药物分子及制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7901885B2 (en) * | 2006-05-09 | 2011-03-08 | Dsm Ip Assets B.V. | Genes and markers in type 2 diabetes and obesity |
WO2008065544A2 (en) * | 2006-09-11 | 2008-06-05 | Mcgill University | Genetic predictors of risk for type 2 diabetes mellitus |
US20110189663A1 (en) * | 2007-03-05 | 2011-08-04 | Cancer Care Ontario | Assessment of risk for colorectal cancer |
US20170029892A1 (en) * | 2009-05-29 | 2017-02-02 | Jay L. Lombard | Methods and compositions for the treatment of post-traumatic stress disorder |
US8355927B2 (en) * | 2010-11-05 | 2013-01-15 | Genomind, Llc | Neuropsychiatric test reports |
WO2012156515A1 (en) * | 2011-05-18 | 2012-11-22 | Rheinische Friedrich-Wilhelms-Universität Bonn | Molecular analysis of acute myeloid leukemia |
US20170253928A1 (en) * | 2013-03-15 | 2017-09-07 | Pathway Genomics Corporation | Method and system to predict response to treatments for mental disorders |
US20140274764A1 (en) * | 2013-03-15 | 2014-09-18 | Pathway Genomics Corporation | Method and system to predict response to treatments for mental disorders |
ES2726650T3 (es) * | 2014-03-14 | 2019-10-08 | Caredx Inc | Métodos de monitorización de terapias inmunosupresoras en un receptor de trasplante |
-
2021
- 2021-02-23 MX MX2022010816A patent/MX2022010816A/es unknown
- 2021-02-23 EP EP21764344.4A patent/EP4106872A4/en active Pending
- 2021-02-23 IL IL296168A patent/IL296168A/en unknown
- 2021-02-23 CA CA3174572A patent/CA3174572A1/en active Pending
- 2021-02-23 BR BR112022017770A patent/BR112022017770A2/pt unknown
- 2021-02-23 CN CN202180031602.1A patent/CN115515680A/zh active Pending
- 2021-02-23 KR KR1020227034374A patent/KR20230005816A/ko unknown
- 2021-02-23 US US17/905,511 patent/US20230193388A1/en active Pending
- 2021-02-23 WO PCT/US2021/019265 patent/WO2021178166A1/en unknown
- 2021-02-23 JP JP2022552541A patent/JP2023515665A/ja active Pending
- 2021-02-23 AU AU2021231683A patent/AU2021231683A1/en active Pending
- 2021-03-05 TW TW110107927A patent/TW202146660A/zh unknown
- 2021-03-05 AR ARP210100576A patent/AR121515A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
CN115515680A (zh) | 2022-12-23 |
WO2021178166A1 (en) | 2021-09-10 |
TW202146660A (zh) | 2021-12-16 |
IL296168A (en) | 2022-11-01 |
EP4106872A1 (en) | 2022-12-28 |
US20230193388A1 (en) | 2023-06-22 |
AU2021231683A1 (en) | 2022-09-22 |
JP2023515665A (ja) | 2023-04-13 |
AR121515A1 (es) | 2022-06-08 |
EP4106872A4 (en) | 2024-04-10 |
CA3174572A1 (en) | 2021-09-10 |
KR20230005816A (ko) | 2023-01-10 |
MX2022010816A (es) | 2022-12-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Gkatza et al. | Cytosine-5 RNA methylation links protein synthesis to cell metabolism | |
Sankowski et al. | Mapping microglia states in the human brain through the integration of high-dimensional techniques | |
Kuan et al. | An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center responders | |
Dias et al. | β-catenin mediates stress resilience through Dicer1/microRNA regulation | |
Wang et al. | Genome-wide differential expression of synaptic long noncoding RNAs in autism spectrum disorder | |
James et al. | Complex epigenetic regulation of engrailed-2 (EN-2) homeobox gene in the autism cerebellum | |
Calligaris et al. | Blood transcriptomics of drug-naive sporadic Parkinson’s disease patients | |
Gavin et al. | Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis | |
Fisher et al. | Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms | |
Munkholm et al. | A composite peripheral blood gene expression measure as a potential diagnostic biomarker in bipolar disorder | |
Peeters et al. | Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting | |
Berge et al. | The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells | |
Berta et al. | Gene expression profiling of cutaneous injured and non-injured nociceptors in SNI animal model of neuropathic pain | |
Katoh et al. | Reciprocal changes of H3K27ac and H3K27me3 at the promoter regions of the critical genes for endometrial decidualization | |
Lagerstedt et al. | H-FABP: A new biomarker to differentiate between CT-positive and CT-negative patients with mild traumatic brain injury | |
Colicino et al. | Telomere length, long-term black carbon exposure, and cognitive function in a cohort of older men: the VA Normative Aging Study | |
Nevalainen et al. | Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90+ study | |
Pasinetti et al. | Select non-coding RNA in blood components provide novel clinically accessible biological surrogates for improved identification of traumatic brain injury in OEF/OIF Veterans | |
Gill et al. | Moderate blast exposure alters gene expression and levels of amyloid precursor protein | |
Fries et al. | Integrated transcriptome and methylome analysis in youth at high risk for bipolar disorder: a preliminary analysis | |
Li et al. | Methyl CpG Binding Domain Ultra‐Sequencing: a novel method for identifying inter‐individual and cell‐type‐specific variation in DNA methylation | |
Kebir et al. | Epigenetic variability in conversion to psychosis: novel findings from an innovative longitudinal methylomic analysis | |
BR112022017770A2 (pt) | Polinucleotídeo isolado; painel de polinucleotídeos isolados; kit que compreende o polinucleotídeo isolado ou painel; microarranjo; reagente; kit que compreende o reagente; kit que compreende o polinucleotídeo isolado ou painel; método de diagnóstico complementar; método para classificar um indivíduo para elegibilidade para um tratamento; método para rastrear um indivíduo ou uma população de indivíduos para um tratamento; método para monitorar um indivíduo durante um tratamento; método para identificar um alvo de fármaco; método para o tratamento de doença ou transtorno do sistema nervoso central (snc) em um indivíduo; uso | |
Jones et al. | The ATR-p53 pathway is suppressed in noncycling normal and malignant lymphocytes | |
Wei et al. | Co-morbidity of personality disorder in schizophrenia among psychiatric outpatients in China: data from epidemiologic survey in a clinical population |