BR112022017484A2 - Processo quimioenzimático para a preparação de um produto de glicose oxidada, processos quimioenzimáticos para a produção de ácido glucárico e para a produção de d-glucono-¿-1,5-lactona, e, processo de fabricação - Google Patents

Processo quimioenzimático para a preparação de um produto de glicose oxidada, processos quimioenzimáticos para a produção de ácido glucárico e para a produção de d-glucono-¿-1,5-lactona, e, processo de fabricação

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Publication number
BR112022017484A2
BR112022017484A2 BR112022017484A BR112022017484A BR112022017484A2 BR 112022017484 A2 BR112022017484 A2 BR 112022017484A2 BR 112022017484 A BR112022017484 A BR 112022017484A BR 112022017484 A BR112022017484 A BR 112022017484A BR 112022017484 A2 BR112022017484 A2 BR 112022017484A2
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BR
Brazil
Prior art keywords
chemioenzymatic
production
peroxidase
oxidized
oxidase
Prior art date
Application number
BR112022017484A
Other languages
English (en)
Inventor
M Lee Toni
Qian Shuai
F Fisher Brian
Downing Sarah
Chakrabarti Gaurab
Hunt Sean
Original Assignee
Solugen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solugen Inc filed Critical Solugen Inc
Publication of BR112022017484A2 publication Critical patent/BR112022017484A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
    • C12Y101/03004—Glucose oxidase (1.1.3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
    • C12Y101/03009—Galactose oxidase (1.1.3.9)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
    • C12Y111/01—Peroxidases (1.11.1)
    • C12Y111/01007—Peroxidase (1.11.1.7), i.e. horseradish-peroxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/99—Miscellaneous (1.14.99)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCESSO QUIMIOENZIMÁTICO PARA A PREPARAÇÃO DE UM PRODUTO DE GLICOSE OXIDADA, PROCESSOS QUIMIOENZIMÁTICOS PARA A PRODUÇÃO DE ÁCIDO GLUCÁRICO E PARA A PRODUÇÃO DE D-GLUCONO-d-1,5-LACTONA, E, PROCESSO DE FABRICAÇÃO. Um processo quimioenzimático para a preparação de um produto de glicose oxidada que compreende colocar a D-glicose em contato com uma enzima selecionada a partir do grupo que consiste essencialmente em galactose oxidase (GAO), glicose oxidase (GOX), polissacarídeo monooxigenase, catalase, peroxidase animal, aldeído oxidase periplasmática (Pao), peroxigenase inespecífica (UPO), lactoperoxidase (LPO), mieloperoxidase (MPO), peroxidase eosinofílica (EPO), peroxidase tireoidiana (TPO), ovoperoxidase, peroxidase salivar, haloperoxidase de vanádio, peroxidase de vertebrados não mamíferos (POX), peroxidasina (Pxd), peroxicina bacteriana (Pxc), peroxinectina de invertebrados (Pxt), peroxidoquerina curta (PxDo), alfa-dioxigenase (aDox), dupla oxidase (DuOx), prostaglandina H sintase (PGHS), ciclooxigenase (CyOx), linoleato diol sintase (LDS), variantes dos mesmos e combinações dos mesmos em condições adequadas para a formação de um intermediário oxidado; e colocar o intermediário oxidado em contato com um catalisador de metal para formar um produto de glicose oxidada.
BR112022017484A 2020-03-06 2021-03-06 Processo quimioenzimático para a preparação de um produto de glicose oxidada, processos quimioenzimáticos para a produção de ácido glucárico e para a produção de d-glucono-¿-1,5-lactona, e, processo de fabricação BR112022017484A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062986447P 2020-03-06 2020-03-06
PCT/US2021/021261 WO2021178935A1 (en) 2020-03-06 2021-03-06 Compositions and methods for production of glucose oxidation products

Publications (1)

Publication Number Publication Date
BR112022017484A2 true BR112022017484A2 (pt) 2022-11-16

Family

ID=77612835

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022017484A BR112022017484A2 (pt) 2020-03-06 2021-03-06 Processo quimioenzimático para a preparação de um produto de glicose oxidada, processos quimioenzimáticos para a produção de ácido glucárico e para a produção de d-glucono-¿-1,5-lactona, e, processo de fabricação

Country Status (10)

Country Link
US (1) US20230121990A1 (pt)
EP (1) EP4114930A4 (pt)
JP (1) JP2023516761A (pt)
KR (1) KR20220151666A (pt)
CN (1) CN115397977A (pt)
AU (1) AU2021231903A1 (pt)
BR (1) BR112022017484A2 (pt)
CA (1) CA3170300A1 (pt)
MX (1) MX2022011053A (pt)
WO (1) WO2021178935A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024129887A1 (en) * 2022-12-13 2024-06-20 Solugen, Inc. Biobased synthesis of glucodiamine
WO2024160906A1 (en) * 2023-02-01 2024-08-08 Coöperatie Koninklijke Cosun U.A. Enzymatic process for the production of aldaric acids

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10319917B4 (de) * 2003-05-05 2009-01-02 Südzucker AG Mannheim/Ochsenfurt Verfahren zur selektiven Kohlenhydrat-Oxidation unter Verwendung geträgerter Gold-Katalysatoren
JP6410721B2 (ja) * 2012-10-05 2018-10-24 コーネル ユニヴァーシティー マクロポーラススカフォールドに埋め込まれたメソポーラス・アセンブリを形成する酵素
EP3200891B1 (en) * 2014-09-29 2020-08-19 Archer-Daniels-Midland Company Preparation and separation of a dicarboxylic acid-containing mixture using a dicarboxylate form of an anion exchange chromatography resin
KR20220154178A (ko) * 2020-03-12 2022-11-21 솔루젠, 인코포레이티드 2,5-푸란 디카르복실산 생산을 위한 조성물 및 방법

Also Published As

Publication number Publication date
EP4114930A4 (en) 2024-04-10
US20230121990A1 (en) 2023-04-20
EP4114930A1 (en) 2023-01-11
AU2021231903A1 (en) 2022-09-29
WO2021178935A1 (en) 2021-09-10
MX2022011053A (es) 2023-03-14
KR20220151666A (ko) 2022-11-15
JP2023516761A (ja) 2023-04-20
CN115397977A (zh) 2022-11-25
CA3170300A1 (en) 2021-09-10

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